Carol Fries Simpson

Carol Fries Simpson, M.D., is an Assistant Professor with dual appointments in the Department of Pediatrics (Hematology/Oncology) and Department of Pathology and Laboratory Medicine at the University of Rochester Medical Center. She specializes in pediatric hematology-oncology and leads translational research focused on lymphoid malignancies.

Education:

• MD: SUNY Upstate Medical University (2012)
• Residency & Chief Residency: University of Rochester Medical Center (2012-2016)
• Fellowship: Pediatric Hematology-Oncology, University of Rochester (2016-2019)

Research Focus: Dr. Simpson investigates genetic mechanisms in acute lymphoblastic leukemia (ALL) and lymphoma using advanced sequencing techniques. Her work aims to personalize cancer therapy by predicting treatment response and minimizing toxicity. Key interests include clonal evolution in B-cell malignancies, novel therapeutic targets, and improving outcomes for high-risk pediatric patients.

Publications Trends: Her recent work (2018-2025) centers on leukemia/lymphoma diagnostics, molecular prognostication, and innovative treatments. Common themes include CAR-T therapy response prediction, transplantation protocols for refractory cases, and liquid biopsy applications. Publications demonstrate consistent focus on translating laboratory findings to clinical practice.

Awards:

• Ruth A. Lawrence Award in Research (2023)
• CTSI Pilot Studies Trainee Award (2018-2019)
• Dean's Fellowship (2017-2019)
• Teaching Awards (2015, 2017)
• Gold Humanism Honor Society (2012)