معرفی
Carlotta Figliola is a CNRS Researcher at the Institute of Chemistry and Processes for Energy, Environment and Health (ICPEES), University of Strasbourg, France, where she conducts cutting-edge research in medicinal chemistry and photodynamic therapy. Her work bridges synthetic organic chemistry, molecular engineering, and biomedical applications, with a focus on developing targeted and activatable photosensitizers for cancer and antimicrobial treatments.
Research Interests:
- Design and synthesis of organic and stimuli-responsive photosensitizers
- Selective photodynamic therapy (PDT) for anticancer and antimicrobial applications
- Molecular engineering of boron complexes (e.g., BODIPYs, BF2-DIPYRs)
- Bioinspired molecules and fluorophores
- Photophysical studies of singlet oxygen and triplet excited states
- Collaborative theoretical and biological evaluation through partnerships
Her recent publications (2023–2024) reflect a strong trend in developing pH-activable, lysosome-targeting agents and novel boron-based fluorophores with tunable photophysical properties. These works emphasize structure-activity relationships, ab initio calculations, and imaging-guided therapy, indicating a multidisciplinary and translational research direction. She also explores enzymatic bioconjugation strategies for nucleic acid labeling, expanding PDT applications into precision medicine.
Scientific Collaborations and Recognition:
- Collaborates with Prof. Denis Jacquemin (University of Nantes) on ab initio calculations
- Works with Prof. Pascal Didier and Dr. Halina Anton (University of Strasbourg) on in vitro biological testing and imaging
- Active contributor to high-impact journals in organic and medicinal chemistry
- Profiles on Google Scholar, ResearchGate, LinkedIn, and ORCID (0000-0001-7299-1083)
Dr. Figliola has advised no listed students yet and has not received any explicitly mentioned scientific awards. She is based in Building R3, Floor 2, Office 4 at ICPEES. Her research is supported by CNRS and collaborative grants, though specific funding sources are not detailed in the text. She is part of a vibrant research environment at ICPEES, contributing to the institute's mission in energy, environment, and health through advanced molecular design.
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