معرفی
Carl J. Johnston, Ph.D., is a **Part-Time Researcher** in the Department of Pediatrics at the University of Rochester School of Medicine and Dentistry. His research focuses on understanding how postnatal lung development interacts with environmental stressors, particularly airborne pollutants, allergens, endotoxins, respirable particulate matter, and irritant gases, to determine their role in childhood pulmonary susceptibility and late-onset diseases.
- PhD in Pharmacology and Toxicology, SUNY Buffalo (2006)
- MS in Toxicology, University of Rochester (1993)
- BA in Biology, Buffalo State College (1987)
His work examines age-dependent signaling pathways activated by multi-pollutant exposures, utilizing techniques such as mRNA analysis, microarray technology, immuno-histochemistry, and in situ hybridization. Key findings highlight the exacerbation of lung injury by combined exposures and the role of immune effector cells.
Recent publications analyze radiation therapy interactions with viral infections, immunomodulatory strategies for pancreatic cancer, and proteomic changes in e-cigarette/vapor exposures. Trends show interdisciplinary work bridging radiation biology, environmental toxicology, and immunotherapy.
- Scientific Award: Outstanding Presentation – Mixtures Specialty Section, SOT Meeting (2012)
His research is supported by NIH grants, with collaborations across multiple institutions. He investigates long-term consequences of neonatal irradiation, skeletal muscle decline post-radiation, and mechanisms of radiation-induced fibrosis.
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