Céline Fiset

Prof. Céline Fiset is a Full Professor at the Faculty of Pharmacy, Université de Montréal, and a researcher at the Institut de cardiologie de Montréal. Her work focuses on cardiac electrophysiology, particularly sex differences in cardiovascular function, hormonal regulation of ion channels, and arrhythmia mechanisms. She leads projects funded by major Canadian health agencies like the Canadian Institutes of Health Research (CIHR) and the Heart and Stroke Foundation. Prof. Fiset has supervised numerous PhD and Master’s students since 1995, exploring topics such as pregnancy-induced arrhythmias, sex-based differences in atrial fibrillation, and hormonal effects on cardiac repolarization.

Research Highlights:

• Expertise in sinoatrial node function, cardiac ion channels, and antiarrhythmic pharmacology.
• Investigates how sex hormones (estrogens, testosterone) modulate cardiac electrical activity.
• Studies arrhythmia mechanisms in transgenic mouse models (e.g., angiotensin II receptor overexpression).
• Examines pregnancy-related cardiac adaptations, such as increased heart rate and atrial remodeling.

Grants & Funding:

• Leading a CIHR-funded project (2021–2028) on estrogen’s role in pregnancy-related arrhythmias.
• Recipient of multiple CRSNG (Natural Sciences and Engineering Research Council) grants for sinoatrial node ion channel studies.
• Collaborates on projects exploring sex-dependent cardiac protection via mTOR pathways.

Advising & Training:

• Supervised over 30 graduate students since 1995, with recent focus on atrial fibrillation mechanisms and pregnancy-related electrophysiology.
• Guides research on translational models (e.g., iPSC-derived cardiomyocytes) to study sex differences in cardiac disease.

Affiliations:

• Member of the Institut de cardiologie de Montréal Research Centre (ICM).
• Associated with the GRUM (University Research Group on Medicines).