Böhm, J.

Böhm, J. is a researcher at the German Cancer Research Center (DKFZ), specializing in colorectal cancer epidemiology and molecular oncology. With multiple publications from 2020-2025 in high-impact journals including Nature Genetics, Nature Communications, and the American Journal of Clinical Nutrition, Böhm contributes to understanding the genetic, metabolic, and nutritional factors influencing colorectal cancer development and outcomes.

Böhm's research focuses on several key areas within colorectal cancer research. The work examines genetic susceptibility through large-scale genomic studies involving over 100,000 cases, metabolomic pathways including tryptophan-kynurenine metabolism and B-vitamin status, and body composition relationships with cancer outcomes. This multi-faceted approach integrates molecular, nutritional, and clinical perspectives to advance precision oncology for colorectal cancer patients.

The publication record shows a strong emphasis on collaborative research through consortia like FOCUS and ColoCare, with studies analyzing biomarkers for cancer prognosis, genetic risk factors across diverse populations, and the relationship between nutritional status and cancer survival. Recent work (2024-2025) continues to advance fine-mapping of colorectal cancer susceptibility genes and metabolomic predictors of mortality.

Böhm's scientific contributions include:

• Multi-omic analysis of over 100,000 colorectal cancer cases for genetic susceptibility studies
• Investigations into tryptophan-kynurenine pathway metabolites as mortality predictors
• Research on vitamin B6 status and colorectal cancer survival outcomes
• Analysis of body composition metrics and quality of life in cancer patients
• Studies of Lynch syndrome mutational profiles under surveillance

As part of the DKFZ research community, Böhm collaborates with international teams across Europe and Asia, contributing to large-scale genomic and epidemiological studies that advance our understanding of colorectal cancer biology and improve patient outcomes through precision medicine approaches.