Burke Neurological Institute

The Burke Neurological Institute is a leading research institution focused on neurological recovery from stroke, spinal cord injury, traumatic brain injury, cerebral palsy, neurodegenerative diseases, and retinal degenerative diseases. Affiliated with Weill Cornell Medicine, the institute conducts interdisciplinary research across Motor, Pain & Sensory, Cognitive, and Vision recovery domains.

Research areas include

• Neurological Recovery: Stroke, Spinal Cord Injury, Traumatic Brain Injury, and Retinal Degenerative Diseases
• Cell Death: Ferroptosis, Epigenetic regulation, and Oxidative Stress
• Drug Discovery: HDAC inhibitors, HIF prolyl hydroxylase inhibitors, and Selenium-based therapeutics
• Research Methods: Cell Death, Drug Discovery, Molecular Studies, Stem Cells, Hypoxia Modeling, Human Biomarker Studies

Key trends in publications involve

• Glucose Restriction and ER Stress in Stroke/Alzheimer's
• Antioxidants like Selenium for Stroke Recovery
• Hypoxic Adaptations in Spinal Cord Injury
• Epigenetic Therapeutics for Neurodegeneration

Notable grants and collaborations include

• $3.1 million NIH funding for spinal cord injury research
• NIH HEAL Initiative grant for non-opioid pain treatments
• Partnerships with Cornell University, Rush Medical College, and Yale School of Medicine

Labs and facilities include

• Ratan Lab (Neural Redox Biology)
• Prusky Lab (Visual Disease and Therapy)
• Cho Lab (Stroke Neuroimmunology)
• Hollis Lab (Motor Recovery)
• Imaging Core
• SCI Core