معرفی
Brianne Caoyonan is an Assistant Professor in the Department of Anesthesiology & Perioperative Care at the University of California, Irvine School of Medicine. Her research focuses on innovative approaches to cancer immunotherapy, particularly through the development of vaccine delivery systems using plasma membrane vesicles.
Her research interests include cancer immunotherapy, vaccine development, molecular immunology, and the application of protein transfer technologies for antigen delivery. Her work aims to enhance antigen-specific immune responses using biologically derived particulate systems, with a focus on breast cancer targets such as HER-2.
The primary article associated with her research area describes a novel method of modifying plasma membrane vesicles (PMVs) with GPI-anchored HER-2 and immunostimulatory molecules (IL-12, B7-1) to induce strong humoral and cellular immune responses in mouse models. These studies demonstrate tumor protection and prolonged antigen persistence, indicating potential for clinical translation in cancer vaccines.
No scientific awards or mentoring activities are mentioned in the available text.
She is involved in research that bridges anesthesiology and immunology, suggesting interdisciplinary collaboration in perioperative cancer care and immune modulation.
