معرفی
Brandon Ruotolo is a Professor of Chemistry and Associate Chair for Research at the University of Michigan Department of Chemistry. His research focuses on developing ion mobility-mass spectrometry (IM-MS) for structural biology, particularly analyzing protein complexes and their interactions. He holds a PhD from Texas A&M University and completed postdoctoral work at the University of Cambridge.
Key research areas include biomacromolecular chemistry, analytical chemistry, and pharmaceutical applications of structural mass spectrometry. His group explores gas-phase protein unfolding (CIU), protein self-assembly, and integrative structural biology. Notable awards include the 2023 Biemann Medal and 2024 Ken Standing Award.
Recent work emphasizes IM-MS integration with other techniques, advancing drug discovery and biotherapeutic characterization. The lab actively mentors students (e.g., Iliana Levesque, Carolina Rojas Ramirez), and collaborates on projects like membrane protein analysis and amyloid formation mechanisms.
Lab resources include advanced mass spectrometry instrumentation and computational tools. Active grants include NSF support for creativity and Agilent Thought Leadership funding. The group's mission is to bridge analytical and structural chemistry for biomedical applications.
