معرفی
Prof. Dr. Bob van de Water is a Professor of Drug Safety Science at Leiden University, where he serves as head of the Cancer Therapeutics and Drug Safety group within the Division of Drug Discovery & Safety at the Leiden Academic Centre for Drug Research (LACDR). His research focuses on understanding the molecular mechanisms underlying drug toxicity and cancer drug resistance.
His primary research interests include:
- Adaptive cellular stress responses
- Cancer drug resistance and metastasis
- Cell signaling pathways
- Drug safety evaluation
- Functional genomics
- High throughput microscopy
- Molecular mechanisms of drug toxicity
- Toxicology
Professor van de Water leads several significant research projects including studies on oncogenic protein tyrosine kinases in breast cancer, live cell imaging-based modeling of cellular toxicity pathways, and identification of novel druggable targets for different breast cancer types. He teaches in the Bio-Pharmaceutical Sciences programs at both BSc and MSc levels, offering courses on drug safety evaluation, signal transduction, and cellular toxicology.
His research group includes current PhD candidates:
- Serkan Aslan
- Sibel Bahtiri
- Linda van den Berk
- Imke Bruns
- Gerhard Burger
Professor van de Water has previously supervised numerous PhD students to completion, including:
- Olivier Béquignon
- Muriel Heldring
- Marije Niemeijer
- Lukas Wijaya
- Luc Bischoff
