Bernhardt L. Trout

Professor Bernhardt L. Trout leads the Molecular Engineering Laboratory at MIT’s Department of Chemical Engineering. His work integrates computational, theoretical, and experimental methods to engineer molecular-level solutions for high-value chemical applications. Key focus areas include continuous pharmaceutical manufacturing, biopharmaceutical formulation, nucleation/crystallization processes, and molecular computational methods.

Education:

• Ph.D. in Chemical Engineering, University of California, Berkeley (1996)
• S.B. and S.M. in Chemical Engineering, MIT (1990, 1990)

Research Interests:

• Pharmaceutical Manufacturing: Developing continuous processes and novel formulation strategies for biologics.
• Nucleation & Crystallization: Molecular-level design of crystals and polymorphic control.
• Computational Methods: Innovating algorithms for reactive processes in complex systems.
• Energy & Environment: Exploring gas hydrate technologies and sustainable manufacturing.

Awards: Over 15 major honors including The Medicine Maker Power List (2015–2017), AIChE Excellence in Process Development Award (2014), and NSF CAREER Award (2000–2004).

Advising & Labs: Directs the Trout Research Group, fostering innovation in molecular engineering. Collaborates on projects like injection molding for pharmaceuticals and freeze-drying optimization.

Active in professional education, offering courses on biotherapeutic stabilization and AI ethics in technology.