Beining Chen

Prof. Beining Chen is a Professor of Medicinal Chemistry at the School of Mathematical and Physical Sciences, University of Sheffield. Holding a PhD in Chemistry from the University of Glasgow (1991), she has pioneered research in computer-aided molecular design and combinatorial chemistry for drug discovery targeting prion diseases (TSEs) and neurodegenerative disorders like Alzheimer’s.

• Education: BSc (1984), MSc (1987) - China; PhD (1991) - University of Glasgow
• Appointments: Research Fellow (Oxford), Lecturer (Cranfield), Lecturer (Sheffield), Professor (Sheffield, 2014)

Her research focuses on stabilizing prion protein conformations and targeting amyloid pathways, securing over £1.15M in Department of Health funding. She also explores natural product chemistry for lead compounds in cardiovascular, CNS, and antiviral research.

Recent publications emphasize de novo drug design, computational proteomics, and structure-activity relationship studies for neurodegenerative diseases. Teaching areas include Medicinal Chemistry, Chemical Biology, and molecular modeling across undergraduate and postgraduate levels.