معرفی
Barbara Strupp is a Professor in the Department of Psychology at Cornell University, with joint affiliations to the College of Arts and Sciences and College of Human Ecology. Her research examines neurodevelopmental trajectories using rodent models and human clinical studies, focusing on nutritional interventions and environmental neurotoxins. She maintains active collaborations with Rush University Medical Center, NYU, UC Santa Cruz, and University of Illinois researchers.
Her primary investigations evaluate how maternal choline supplementation during pregnancy influences cognitive development in Down syndrome models and neurotypical populations, revealing lasting improvements in attention, spatial memory, and emotional regulation. Parallel research analyzes developmental manganese exposure's neurotoxic effects on attention and motor function, demonstrating therapeutic efficacy of methylphenidate through catecholaminergic receptor modulation. Studies integrate behavioral phenotyping with neural mechanism analyses across lifespan development.
Recent publication trends (2019-2025) highlight longitudinal human trials confirming choline's cognitive benefits in school-aged children, mechanistic rodent studies elucidating choline's neuroprotective pathways in Down syndrome models, and neuropharmacological interventions counteracting manganese-induced deficits. Research consistently bridges nutritional science, neurotoxicology, and developmental disorder therapeutics.
