Baran Ersoy

Baran Ersoy is an Assistant Professor of Metabolism in Medicine at Weill Cornell Medical College's Department of Medicine, with his Assistant Professor appointment ongoing since 2016 and an upcoming promotion to Associate Professor starting in 2025. His research program investigates metabolic disorders through molecular mechanisms, focusing on the interplay between lipid metabolism, organ dysfunction, and metabolic diseases.

Education

• Ph.D., University of California, San Francisco (2009)
• B.S., University of Kansas (2001)

Research Focus

Dr. Ersoy's research explores fundamental metabolic processes with emphasis on:

• Molecular pathways in non-alcoholic fatty liver disease (NAFLD) progression
• Thioesterase-mediated regulation of lipid metabolism and ER stress
• Genetic mechanisms underlying obesity and insulin resistance
• Adipose tissue thermogenesis and fatty acid activation
• Hepatic gluconeogenesis regulation through microbiome interactions
• Ceramide biosynthesis in cardiometabolic diseases

Research Publications

His publication portfolio demonstrates consistent focus on metabolic dysregulation across multiple organ systems, with recent work (2020-2025) emphasizing: thioesterase functions in liver metabolism, genetic obesity pathways, NAFLD mechanisms, and novel intersections between lung injury and metabolic disorders. Methodologies span molecular biology, transgenic models, and clinical-translational approaches.

Grants and Funding

• Principal Investigator: Them1 Inhibitors for NAFLD Management (NCI, 2023-2028)
• Key Personnel: Gut Microbiome Regulation of Hepatic Gluconeogenesis (NIDDK, 2022-2027)
• Principal Investigator: Thioesterase-mediated Lipotoxicity in Liver/Adipose Tissue (NIDDK, 2021-2026)