B.C. Jacobs

B.C. Jacobs is a Full Professor at Erasmus MC, affiliated with both the Department of Immunology and the Department of Neurology. His research is centered on autoimmune and inflammatory neuropathies, with a primary focus on Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyneuropathy (CIDP). He has authored or co-authored over 300 research outputs, demonstrating sustained academic productivity and leadership in neuroimmunology.

The research interests of Prof. Jacobs span immunological mechanisms in neurological disorders, particularly the role of infections such as Campylobacter jejuni in triggering autoimmune responses, the genetic basis of immune receptor variation, and the therapeutic effects of intravenous immunoglobulin (IVIG). His work also explores clinical biomarkers like neurofilament light chain and regulatory T cells to predict disease outcomes and treatment responses.

The recent publications reveal a strong trend toward translational research, integrating molecular immunology with clinical neurology. Key themes include biomarker validation, patient-centered outcome measures, and improving prognostic models in peripheral neuropathies. This body of work reflects a multidisciplinary approach combining clinical data, immunological assays, and genetic analysis.

Prof. Jacobs has supervised 15 research works, indicating an active role in mentoring the next generation of scientists and clinicians in neurology and immunology, although specific names of students are not provided in the text. His collaborations span multiple institutions and countries, as reflected in co-authorship with researchers across diverse specialties.

He is also engaged in public outreach, as evidenced by media contributions on treatable forms of polyneuropathy, which were disseminated through professional public engagement channels and picked up by news outlets and social media platforms.