معرفی
Aurea Martins Bach is a Postdoctoral Researcher at the Nuffield Department of Clinical Neurosciences (NDCN), University of Oxford, affiliated with the Microstructural Imaging group and Oxford Motor Neuron Disease Centre. Her work bridges molecular neuroscience and clinical neurology through cutting-edge neuroimaging and genetic approaches.
Her research focuses on neurodegenerative mechanisms in ALS and FTD, particularly:
- TDP-43 and FUS proteinopathies
- Neurodevelopmental consequences of mutation carriers
- Systemic metabolic alterations in neurodegeneration
- Quantitative neuroimaging biomarkers
Recent publications (2022-2023) demonstrate integration of transgenic models, metabolic profiling, and large-scale imaging genetics. Key trends include elucidating pathological cascades from protein misfolding to cognitive deficits and developing imaging-based diagnostic tools.
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Dr. Bach actively contributes to Oxford's Motor Neuron Disease Centre and Microstructural Imaging group, utilizing multidisciplinary methodologies to investigate disease mechanisms and potential therapeutic targets in motor neuron disorders.