معرفی
Aude Bernheim is a microbiologist and independent research group leader at the Pasteur Institute in Paris, leading the 'Molecular Diversity of Microbes' (MDM) laboratory. She is affiliated with the Department of Microbiology and the Pole – Phylogeny, Algorithms, (Meta)Genomics, Evolution, where she conducts cutting-edge research on bacterial immunity and antiphage defense systems.
Research Interests: Her work focuses on understanding the diversity and molecular mechanisms of bacterial immune systems, particularly how bacteria defend against bacteriophages. She investigates the conservation of these defense systems across all domains of life, including potential parallels in human immunity. Her research integrates bioinformatics, genomics, phylogenetics, bacterial genetics, and phage biology to uncover novel immune genes and mechanisms.
Publication Trends: Her recent publications, appearing in high-impact journals such as Science, Nature, Cell, and Nature Microbiology, reflect a strong emphasis on discovering and characterizing novel antiphage defense systems, understanding their evolutionary origins, and exploring their conservation across life. Key themes include CRISPR alternatives, retrons, viperin, and the prediction of phage-host interactions using genomic data.
- Rosalind Franklin Young Investigator Prize
- Jacques Monod Prize
- Collège de France Young Researcher Prize
- Elected Member of the European Academy of Microbiology
- Member of the Presidential Council
Advising and Grants: Dr. Bernheim mentors a dynamic team including PhD students and postdoctoral fellows. Her research is supported by competitive grants, enabling interdisciplinary studies at the intersection of microbiology, evolution, and immunology. She actively promotes citizen science and inclusivity in research.
Labs and Teams: She leads the MDM Lab at the Pasteur Institute, which includes researchers such as Jean Cury, Rachel Lavenir, Helena Shomar, Ernest Mordret, Alba Herrero del Valle, Florian Tesson, Heloise Georjon, Hugo Vaysset, and Alexandre Hervé, fostering a collaborative environment for microbial genomics and immunity research.
