Astrid Johannesson Hjelholt

Astrid Johannesson Hjelholt is a Physician Scientist at Aalborg University, affiliated with The Faculty of Medicine, Department of Clinical Pharmacology, and practicing as a physician at Aalborg University Hospital. Her research spans multiple disciplines at the intersection of clinical medicine, pharmacology, and statistical genetics.

Dr. Hjelholt's research interests include:

• Genetic architecture and fine mapping of complex diseases
• Clinical trials methodology, particularly placebo-controlled studies
• Migraine treatment and neuropharmacology
• Type 1 diabetes interventions in pediatric populations
• Artificial intelligence applications in drug information systems

Her recent publications reveal a strong methodological focus on Bayesian statistical approaches applied to genetic research, alongside clinical investigations in migraine treatment and diabetes management. She has developed advanced techniques for gene set prioritization and genetic fine mapping while maintaining active clinical research through multiple trials including the INVITED study for type 1 diabetes and a cabergoline migraine treatment pilot.

Dr. Hjelholt's work has received notable attention across academic and public spheres, with publications picked up by news outlets and widely shared on social media platforms including X (formerly Twitter) where one study was posted by 14 users. Her research appears in high-impact journals including PLOS Genetics, PLOS ONE, BMJ Open, and the Danish Medical Journal.

Her scientific contributions encompass:

• Development of Bayesian linear regression models for genetic analysis
• Design and execution of placebo-controlled clinical trials
• Evaluation of AI tools for clinical pharmacology applications
• Investigation of novel treatments for neurological and endocrine conditions