معرفی
Asparuh Nikolov serves as an Associate Professor at the Medical University of Pleven, Bulgaria, within the Faculty of Pharmacy's Department of Medical Physics, Biophysics, Pre-clinical and Clinical Sciences. His academic career integrates clinical medicine with advanced biomarker research across cardiovascular and obstetric disciplines.
Dr. Nikolov's research interests focus on:
- Cardiovascular biomarker discovery in pregnancy complications (particularly preeclampsia)
- Extracellular matrix remodeling in heart failure and hypertension
- Lipid metabolism and atherogenic indices in cardiovascular risk assessment
- Diabetes-hypertension comorbidity and microvascular complications
- Matrix metalloproteinases (MMPs) and tissue inhibitors (TIMPs) as diagnostic tools
Analysis of his 2022-2025 publications reveals a concentrated effort to translate biomarker research into clinical applications. His work demonstrates consistent investigation of serum biomarkers—especially MMPs, TIMPs, and collagen/elastin turnover products—in predicting cardiovascular risks in preeclampsia survivors, heart failure patients, and diabetic hypertensives. Recent studies increasingly examine longitudinal biomarker changes and their correlations with imaging parameters, indicating a shift toward integrated diagnostic approaches.
Dr. Nikolov maintains active research collaborations within Medical University of Pleven's medical science framework, contributing significantly to regional medical literature through publications in specialized cardiology, obstetrics, and diabetes journals.
