Arryn Taylor Blaine

Arryn Taylor Blaine, Ph.D., is a Lecturer in the Department of Pharmaceutical Sciences at the University of Kentucky. Her expertise spans opioid pharmacology, drug discovery, and chemistry education, with a strong research background in medicinal chemistry and molecular pharmacology. She is actively involved in undergraduate teaching and educational research, contributing to both academic and clinical advancements in her field.

Education:

• Ph.D. in Medicinal Chemistry & Molecular Pharmacology from Purdue University
• Bachelor's degree in Biochemistry from Purdue University

Research Focus:

Dr. Blaine's research is centered on the pharmacology of opioid receptors, particularly the delta and mu subtypes. She investigates receptor signaling pathways, ligand-receptor interactions, and the development of novel therapeutic agents targeting opioid receptors. Her work also explores the behavioral and cellular effects of opioid agonists, with implications for treating addiction and neurological disorders.

Her studies delve into the structural and functional aspects of opioid receptor modulation, including the role of β-arrestin isoforms in receptor signaling and seizure induction. She has contributed to the development of new chemotypes for opioid receptor agonists and evaluated potential treatments for alcohol use disorder using kratom derivatives.

Scientific Contributions:

Dr. Blaine has published extensively on opioid receptor pharmacology, with her recent work focusing on novel agonist chemotypes and the neurochemical impacts of psychoactive substances. Her research bridges the gap between basic science and clinical application, aiming to improve therapeutic strategies for opioid-related disorders.

Professional Experience:

• Lecturer, Department of Pharmaceutical Sciences, University of Kentucky
• Chemistry Instructor, Ivy Tech Community College, Indianapolis, Indiana
• Technical Writer, Intellectual Property Department, Taft Stettinius & Hollister LLP

Labs and Teams:

Dr. Blaine is affiliated with the University of Kentucky's Department of Pharmaceutical Sciences, where she engages in collaborative research and teaching activities. Her work supports the department's mission to advance pharmaceutical education and research.