معرفی
Arnaldo Serrano is an Adjunct Professor in the Department of Chemistry at the University of Notre Dame's College of Science since 2025, previously serving as Assistant Professor from 2017 to 2025. His research focuses on developing optical methods to study biological systems at the molecular level, with expertise in two-dimensional infrared spectroscopy and ultrafast optical techniques.
His educational background includes a Ph.D. in Chemistry from the University of Pennsylvania (2013) and a B.A. in Chemistry from Rutgers University (2007).
- Ph.D. in Chemistry, University of Pennsylvania (2013)
- B.A. in Chemistry, Rutgers University (2007)
Serrano's research program centers on applying advanced spectroscopic methods to investigate biomolecular structure and dynamics. Key areas include the effects of divalent cations on peptide groups, liquid-liquid phase separation driving peptide folding, detection of cross-α amyloid polymorphs relevant to bacterial biofilms, and enhancing spatial resolution of infrared imaging for complex biological environments. His work bridges physical chemistry and biophysics to address fundamental questions in molecular interactions.
Recent publications demonstrate consistent focus on biophysical chemistry and optical methodology development, with increasing emphasis on amyloid polymorphism and imaging applications. The research integrates experimental spectroscopy with computational modeling to elucidate molecular mechanisms in peptide folding and aggregation.
Scientific awards include:
- CAREER Award, National Science Foundation (2023)
- ACS PHYS Division Postdoctoral Research Award (2015)
- Hans Neurath Outstanding Promise Award (2015)
Serrano's research is supported by significant grants including the NSF CAREER award, which funds his work on advancing infrared imaging techniques. While specific student names aren't listed, he has advised graduate researchers in Notre Dame's chemistry program. His collaborative approach is evident through co-authorship with institutions like University of Wisconsin-Madison and external collaborators in structural biology.
His laboratory maintains advanced ultrafast laser systems for two-dimensional infrared spectroscopy, with ongoing development of imaging capabilities for biological applications. Current efforts focus on applying these techniques to heterogeneous environments including tissues and bacterial biofilms, with potential implications for understanding infectious disease mechanisms.
