معرفی
Anđela Horvat is an Assistant Professor at the Ruđer Bošković Institute's Division of Molecular Medicine, where she leads research in the Laboratory for Protein Dynamics. She contributes to the University Postgraduate Interdisciplinary Doctoral Study of Molecular Biosciences (University of Osijek, Croatia) as a lecturer and mentors students in cancer biology.
- PhD in Biomedicine and Healthcare (2015), University Postgraduate Interdisciplinary Doctoral Study of Molecular Biosciences, Josip Juraj Strossmayer University of Osijek, University of Dubrovnik, and Ruđer Bošković Institute
- B.Sc. in Molecular Biology (2007), Faculty of Natural Sciences and Mathematics, University of Zagreb
- II High School, Split (2001), and Elementary School "Ostrog", Kaštel Lukšić (1997)
Her research focuses on the p53 family isoforms' roles in cancer development, particularly in melanoma and gastric/esophageal tumorigenesis. Key areas include:
- Autophagy regulation in cancer cells
- Senescence and cell cycle control
- DNA damage response mechanisms
- Targeted therapy resistance in melanoma
- Functional interplay between p53 isoforms and p73/p63
- Nanoparticle interactions with cancer cell cycles
Her publication trends emphasize molecular oncology, specifically p53 family dynamics in therapy resistance, oxidative stress-induced DNA damage, and mitochondrial protein functions in tumor cells. Notable collaborations include studies on NME6 and ITIH5 roles in melanoma resistance.
Scientific awards and honors:
- 2024 HDIR-7 Conference participation (3 abstracts)
- 2022 HDIR-6 Conference abstracts
- 2018 EACR Conference bursary
- 2014 EACR Poster Prize
- 2014 FEMS Young Scientist Grant
- Multiple conference abstracts at p53/p73 workshops (2010-2024)
Horvat has supervised diploma theses and taught courses such as "Methods in molecular biology and medicine" and "Cell cycle control, genome integrity maintenance and cancerogenesis" since 2011. She collaborates with international research teams and maintains memberships in EACR, HDIR, HDBMB, and Croatian Microbiological Society.
