Anne Tybjærg-Hansen

Anne Tybjærg-Hansen serves as a Clinical Professor in the Department of Clinical Medicine at the University of Copenhagen's Faculty of Health and Medical Sciences. Her research is conducted within the Clinical Biochemistry division, with physical locations at Blegdamsvej 9 (2100 Copenhagen Ø) and Blegdamsvej 3 (2200 Copenhagen N). She maintains an active research profile with 403 documented publications, primarily focused on cardiovascular genetics and epidemiology.

Her research interests center on Cardiovascular Genetics, Genetic Epidemiology, and Mendelian Randomization methodologies. Tybjærg-Hansen investigates the genetic underpinnings of atherosclerosis, valvular heart disease, dementia risk, and familial hypercholesterolemia using large population cohorts including the Copenhagen General Population Study and Copenhagen City Heart Study. Her work bridges genetic discoveries with clinical applications, particularly in risk prediction and primary prevention strategies.

Analysis of her recent publications reveals a strong emphasis on translating genetic findings into clinical practice, with particular focus on cardiovascular risk prediction models, gene-disease causal relationships, and therapeutic implications of genetic variants. Her collaborative network spans multiple international consortia, with frequent co-authorship with prominent researchers including B.G. Nordestgaard and R. Frikke-Schmidt.

Her research group actively contributes to major clinical guidelines and has established significant expertise in Mendelian randomization approaches to establish causality in disease mechanisms. Current projects include developing absolute risk charts for aortic valve disease prevention and investigating the relationship between lipid metabolism and various disease outcomes.