معرفی
Angelo Sassaroli is a Research Assistant Professor in the Department of Biomedical Engineering at Tufts University. He leads the Diffuse Optical Imaging of Tissue (DOIT) Lab, focusing on quantitative modeling of light propagation, medical imaging instrumentation, and near-infrared spectroscopy techniques. His work bridges theoretical analyses, experimental studies, and clinical applications in brain/muscle hemodynamics.
Education:
- PhD in Physics, University of Electro-Communications, Tokyo, Japan (2002)
- Bachelor's in Physics, University of Florence, Italy (1996)
His research centers on diffuse optical tomography and near-infrared spectroscopy, with emphasis on depth-sensitive techniques like dual-slope methods and coherent hemodynamics spectroscopy. Key innovations include Monte Carlo simulations for photon transport, self-calibrated measurement systems, and applications in functional brain imaging and tissue oximetry. The DOIT Lab develops novel instrumentation for frequency-domain NIRS, enabling non-invasive monitoring of cerebral and muscular perfusion.
Recent publications (2023-2025) demonstrate a strong focus on advancing Monte Carlo methodologies, dual-slope/double-ratio techniques, and depth-resolved hemodynamic measurements. These works collectively enhance spatial accuracy in optical diagnostics and address challenges in clinical translation.
No scientific awards are mentioned in available materials.
He advises PhD, MS, and undergraduate researchers in the DOIT Lab, which maintains active collaborations and presents at major conferences (e.g., SPIE Photonics West). The lab develops open-source tools and participates in academic initiatives like the Tufts Optics Research Club.
The DOIT Lab specializes in coherent hemodynamics spectroscopy and frequency-domain NIRS, operating from the Science and Technology Center at Tufts. Research spans light-tissue interaction modeling, instrument design, and clinical pilot studies for brain/muscle monitoring.
