Andrij Tolmachev

Andrij Tolmachev is a Professor and Director of the Chemico-Biological Center at Taras Shevchenko National University of Kyiv, Ukraine, where he has worked since 2003. Previously, he held roles ranging from Engineer to Leading Researcher at the Institute of Organic Chemistry, National Academy of Sciences of Ukraine (1979–2002).

Research Interests: Tolmachev specializes in the synthesis, characterization, and optimization of physiologically active substances. His work encompasses

• Heterocyclic hydrazides, amines, and amides
• Fluorine-containing compounds with unique biological properties
• Sulfochlorides and enamine derivatives
• NMR spectroscopy for structural analysis
• LCMS methods for purity characterization
• Development of analytical methods for environmental and material studies

Article Trends: His recent publications focus on parallel synthesis strategies, regioselective reactions, and fluorinated compound development. Keywords include heterocyclic chemistry, trifluoromethyl synthesis, and pharmaceutical intermediates. Subfields highlight reductive amination, condensation agents, and scalable industrial methodologies.

Students & Collaborations: Tolmachev leads a research group with students and collaborators involved in method development, including

• Ryabukhin S.V.
• Bogolubsky A.V.
• Mykhailiuk P.K.
• Komarov I.
• Shishkin O.
• others

Labs & Teams: He directs the Chemico-Biological Center at Taras Shevchenko University, focusing on industrial-scale synthesis and competitive product development for global markets.