Andrew McKeon

Andrew McKeon is a Professor of Neurology and Laboratory Medicine and Pathology at Mayo Clinic College of Medicine and Science in Rochester, Minnesota. He co-directs the Neuroimmunology Laboratory and specializes in immune-mediated central nervous system diseases, including autoimmune encephalitis, ataxias, movement disorders, paraneoplastic syndromes, and stiff-person syndrome. Certified by the American Board of Medical Laboratory Immunology, he focuses on antibody biomarker discovery, clinical trials, and diagnostic criteria development.

• MD, Neuroimmunology (2011) - University College Dublin
• Autoimmune Neurology Fellowship (2009) - Mayo Clinic
• Movement Disorders Fellowship (2007) - Mayo Clinic
• MB BCh/BAO (2000) - University College Dublin

His research centers on autoimmune neurological disorders, with three major domains:

• Diagnostic Innovation: Developing criteria for paraneoplastic syndromes and autoimmune encephalitis while addressing misdiagnosis challenges
• Biomarker Discovery: Validating novel antibodies like GAD65 and MOG through laboratory research
• Clinical Trials: Testing therapeutic approaches for stiff-person syndrome and other autoimmune CNS conditions

Recent publications highlight:

• 2024 review on autoimmune seizure disorders
• 2024 analysis of paraneoplastic movement disorders
• 2023 diagnostic criteria for stiff-person spectrum disorders

Scientific honors include:

• Grass Foundation-American Neurological Association Award (2013)
• Top 5% abstract at American Academy of Neurology (2009)
• Department of Neurology Clinical Research Award (2008)

As co-director of Mayo's Neuroimmunology Laboratory, he leads both clinical service development and multi-institutional research collaborations. His work bridges laboratory medicine and neurology through 15+ years of clinical research at Mayo Clinic.