معرفی
Dr. Andreas Tzakos is a Professor in the Department of Chemistry at the University of Ioannina, Greece, where he leads a research group focused on medicinal chemistry and drug discovery. His laboratory operates under ISO:17025 accreditation (BAC LAB) and specializes in developing bioimaging agents, drug delivery systems, and theranostic compounds for cancer treatment. His research integrates organic synthesis, biophysical techniques, and computational methods to address challenges in human health and disease.
Dr. Tzakos's research spans multiple areas of medicinal chemistry including
- Near InfraRed Imaging agents (NIRI, NIRII, SWIR) for cancer theranostics
- Drug delivery vehicles and ProDrugs development
- Peptide-Drug Conjugates, prodrugs, and small ligands design
- Natural products formulation to enhance therapeutic potency
- Pharmacokinetics and bioanalysis using LC-MS platforms
His publications reveal a strong focus on cancer theranostics, with particular emphasis on targeted drug delivery, molecular imaging, and the development of novel compounds with triple antiplatelet activity. The research demonstrates expertise in NMR spectroscopy, computational modeling, and the application of natural products in drug discovery.
His scientific achievements have been recognized with numerous awards including:
- Leonidas Zervas Award (2004)
- Gardiki-Kouidou Award (2007)
- EMBO long term fellowship & Medical Research Council fellowship (2004-2008)
- A prestigious Academy of Athens award in cancer/heart diseases research (2018)
Dr. Tzakos serves on the editorial boards of several international journals including Molecules, Biochemistry & Pharmacology: Open Access, and E-Journal of Chemistry. He is also an active reviewer for numerous peer-reviewed journals focused on drug discovery, medicinal chemistry, cancer, and biophysics, and serves as an expert evaluator for national and international research proposals including H2020 projects. His laboratory has developed several patented technologies including electronic tuning methodology for GPCR ligands and systems for natural product analogues production.
The Bioanalysis and Pharmacokinetics Laboratory (BAC LAB) he directs operates under ISO/IEC:17025 accreditation, providing high-quality analytical services for drug development research. His team has also developed several computational tools including PRESS (Protein S-Sulfenylation server), DIAB-DB (a database for diabetes drug prediction), and multidimensional fingerprint analysis software for complex mixture assignment.
