معرفی
Professor Andrea Crisanti is a leading academic in Molecular Parasitology at Imperial College London's Department of Life Sciences (Faculty of Natural Sciences). His research focuses on developing gene drive technologies to combat malaria by genetically modifying mosquitoes. His lab demonstrated CRISPR/Cas9-driven population suppression via targeting the doublesex gene, which disrupts female development and could eliminate malaria vectors. Recently, he coordinated the groundbreaking Vo' Euganeo study on early SARS-CoV-2 outbreak management, informing national and international pandemic strategies.
- Affiliations: Imperial College Network of Excellence in Malaria, Infection and Immunity, Vaccine Research Network
- Led the development of synthetic biology tools for vector control and agricultural pest management
- Co-developed Y chromosome-linked gene drives and anti-CRISPR safeguards
- Contributed to WHO-endorsed guidelines for mosquito containment facilities
Research interests span molecular mechanisms of mosquito reproduction, gene drive evolution, and translational applications of synthetic biology in public health. His lab also engages in community outreach through exhibitions and school programs.
Notable collaborations include:
- Target Malaria Consortium
- Italian Veneto Regional Health Task Force
- European Infravec2 initiative
Laboratory infrastructure includes advanced molecular biology facilities and large-scale mosquito testing environments. Funded by major grants from Wellcome Trust, EU Horizon programs, and philanthropic organizations.
