معرفی
Ana Rita Seabra is a Post-Doctoral Researcher at CIBIO-InBIO, University of Porto, Portugal. She works on nitrogen metabolism in plants, particularly focusing on legumes, and explores how post-translational modifications like S-nitrosation regulate key enzymes such as glutamine synthetase (GS). Her research aims to improve sustainable agricultural practices through innovative plant breeding technologies.
Education:
- BSc in Biochemistry (Applied Biochemistry), 2004, University of Porto
- PhD in Biology, 2012, University of Porto (thesis on GS isoenzymes in Medicago truncatula at IBMC-Porto)
Research Focus:
- Differential regulation of GS isoenzymes by nitric oxide (NO)-derived modifications
- Molecular mechanisms of S-nitrosation in plastid-located GS enzymes
- Role of GS in nitrogen fixation and plant defense responses
- Structural analysis of GS active sites via X-ray crystallography and mutagenesis
Publications Trends:
- Investigates NO signaling in plant metabolism, linking enzymatic regulation to physiological outcomes
- Elucidates cysteine residues' functional roles in GS activity using mass spectrometry and site-directed mutagenesis
- Examines interactions between nitrogen assimilation and oxidative stress responses
Supervision:
- Co-supervised Anette Garrido's MSc thesis on GS signaling proteins in Medicago truncatula (2019)
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