معرفی
Ana Marcela serves as an Assistant Professor in the Department of Agrochemistry and Environment at Miguel Hernández University of Elche, Spain. She conducts research within the Structure-function relationships in membrane proteins group at the Ion Channels: Structure & Function Laboratory (Lab 2.9), focusing on biophysical characterization of membrane proteins and ion channels.
Her research spans Membrane Proteins, Ion Channels, Biophysics, Biochemistry, Lipid-Protein Interactions, and Structural Biology. She employs advanced fluorescence methodologies including homo-FRET, time-resolved spectroscopy, and equilibrium binding studies to investigate conformational dynamics in potassium channels (particularly KcsA), lipid modulation of channel function, and intrinsically disordered proteins like NUPR1 and PADI4. Her work bridges fundamental biophysics with cancer biology through studies of lipid-enzyme interactions.
Analysis of her 2021-2025 publications reveals consistent focus on ion channel dynamics, with particular emphasis on selectivity filter mechanisms, gating cycles, and lipid-protein interactions. Key themes include pH-induced conformational changes in potassium channels, anionic phospholipid effects on channel inactivation, and biophysical characterization of cancer-related enzymes like PADI4 using structural and biochemical approaches.
No scientific awards were mentioned in the provided information.
No information regarding student advisees or research grants was provided in the source material, though her active teaching role in pharmacy programs indicates ongoing academic supervision responsibilities.
She maintains active research operations within the Ion Channels: Structure & Function Laboratory (Lab 2.9), collaborating with the Structure-function relationships in membrane proteins research group while utilizing specialized fluorescence methodologies for membrane protein characterization.
