Alyssa Pyun

Alyssa Pyun is Assistant Professor of Clinical Surgery at USC specializing in complex endovascular aortic repair. Her research advances physician-modified endografts, iliac branch devices, and hybrid techniques for thoracoabdominal aneurysms and connective tissue disorders.

Clinical innovations include:

• Off-the-shelf multibranch endoprosthesis deployment
• Rescue techniques for endograft failure
• Frailty assessment in aortic surgery
• Distal seal zone optimization in Marfan syndrome

Publication analysis demonstrates leadership in multicenter studies evaluating physician-modified devices for complex aortic pathologies. Technical contributions encompass novel deployment methods, complication management algorithms, and hybrid approaches. Health services research examines limb preservation models and regulatory frameworks for vascular devices. Current work develops predictive models for frail patients undergoing endovascular repair.