Alla Grishok

Alla Grishok is an Associate Professor at Boston University, focusing on gene regulation by RNA and chromatin. Her laboratory investigates the metazoan DOT1L methyltransferase complex, linking its roles in development, cancer, and mitochondrial gene regulation.

• PhD: University of Massachusetts
• Postdoctoral Training: MIT

Research interests include:

• Chromatin-modifying complexes
• RNA interference (RNAi) pathways
• Transgenerational epigenetic inheritance
• Crosstalk between DOT1L and MYC in gene regulation
• Developmental consequences of chromatin and RNAi dysregulation

Recent publications highlight her work on DOT1L's role in enhancer regulation, non-coding transcriptomes, and mitochondrial health using C. elegans, mammalian cells, and zebrafish models.

Lab members include PhD students Thomas Liontis and Karol Newalaniec, Postdoctoral Associate Gian Paolo Sepulveda, and undergraduate researchers.