Alissa Bleem

Alissa Bleem serves as a Researcher III in Biological Science at the National Renewable Energy Laboratory (NREL), specifically within the Renewable Resources and Enabling Sciences Center focusing on Bioenergy Research. Her work bridges protein engineering, synthetic biology, and microbial systems to develop sustainable bio-based solutions.

Her research interests span protein engineering and biophysics in microbial systems, with particular focus on high-throughput platforms for protein design, computational protein design for synthetic biology applications, and engineering novel microorganisms for high-value product production. Key areas include metabolic engineering, lignin valorization, and microbial catabolism of complex substrates.

Analysis of her publication trends shows strong emphasis on circular bioeconomy approaches, particularly in converting waste feedstocks into valuable products through engineered microbial systems. Her work frequently involves Cupriavidus necator and Sphingobium lignivorans as model organisms for bioconversion processes, with applications in sustainable food systems and renewable chemical production.

Her scientific contributions demonstrate expertise across protein engineering, microbial metabolism, and bioprocess development, with publications appearing in high-impact journals including Nature Communications, Green Chemistry, and Metabolic Engineering.

Dr. Bleem holds a PhD in Bioengineering from the University of Washington and a Bachelor's degree in Chemical Engineering from Montana State University, providing her with a strong foundation in both biological and engineering principles essential for her interdisciplinary research.