Alexis Boulinguiez

Alexis Boulinguiez is a Postdoctoral Researcher at the Department of Biological Sciences, Royal Holloway, University of London. His research focuses on muscular dystrophies, particularly Duchenne and Oculopharyngeal types, investigating molecular mechanisms such as periostin expression, microdystrophin administration, and gene therapy efficacy. He explores how interventions like exercise and protein folding strategies impact muscle pathology and fibrosis.

Research Projects:

• Protein folding strategies to enhance microdystrophin expression in Duchenne Muscular Dystrophy (2024–2026, AFM Telethon-funded)
• Proof-of-concept demonstration combining dystrophin restoration and periostin manipulation (2023, collaborative research)

Key Research Themes: Gene therapy, skeletal muscle biology, fibrosis mechanisms, and dystrophinopathies. His work bridges molecular biology with translational approaches to address muscle degeneration.