Alexey V. Terskikh

Professor Alexey V. Terskikh is a Future Health Research & Innovation Distinguished Fellow, Group Leader of the Chromatin and Ageing Laboratory, and Professor at the UWA Medical School of The University of Western Australia (UWA). His research focuses on epigenetics, aging, and neurogenesis through advanced imaging and computational techniques.

Education:

• PhD in Molecular Immunology (1997), University of Lausanne
• Postdoctoral Research (2002), Stanford University (Irv Weissman Laboratory)

Research Interests:

• Epigenetic regulation of cellular identity
• Single-cell chromatin organization
• ImAge biomarker of aging
• Zika virus pathogenesis
• Computational modeling of aging trajectories
• Deep learning in medical imaging

Notable Contributions:

• Development of MIEL (Microscopic Imaging of Epigenetic Landscapes)
• Creation of ImAge (image-based chromatin and epigenetic age) technique
• Identification of chloroquine as a Zika virus treatment
• Discovery of overlapping genetic programs in hematopoiesis and neurogenesis

Scientific Awards:

• Future Health Research & Innovation Distinguished Fellow

Publications:

• 2024: ImAge as a single-cell aging biomarker
• 2023: Dual function of Zika virus protease
• 2019: Epigenetic imaging for drug discovery
• 2017: Chloroquine repurposing for Zika virus
• 2015: SOX2 in hippocampal neurogenesis
• 2011: SOX2 in sensory neurogenesis
• 2011: Primary cilia in hippocampal progenitors
• 2001: Hematopoietic-neural genetic parallels
• 2000: Fluorescent timer protein