معرفی
Aleksandra Skirycz is an Associate Professor at the Department of Biochemistry & Molecular Biology, Michigan State University, and a key member of the Molecular Plant Sciences Program. Her research focuses on deciphering the complex roles of metabolites in organismal health, primarily in plants but also in other model organisms like Arabidopsis and E. coli.
- Academic Rank: Associate Professor
- Department: Biochemistry & Molecular Biology
- University: Michigan State University
- Email: skirycza@msu.edu
Research Focus
The Small-molecule Regulation Lab employs biochemical methods, mass-spectrometry-based proteomics, and metabolomics to map protein-metabolite interactomes. Key areas include:
- Metabolite functional characterization
- Stress resilience mechanisms
- Single-cell and single-nucleus RNA sequencing
- Omics integration for systems biology
- Role of dipeptides and cyclic metabolites
- Regulation of photosynthesis and glycolysis
Recent Publication Trends
Aleksandra's recent work spans 2025 and 2024, emphasizing metabolite-protein interactions across species. Notable trends:
- Interdisciplinary methods (e.g., co-fractionation MS)
- Stress-induced metabolic adaptations in plants
- Therapeutic applications of metabolites
- Evolutionarily conserved regulatory mechanisms
- Development of tools like SLIMP and PROMISed for interactome analysis
- Focus on drought tolerance in crops like cotton and sorghum
Laboratory Overview
The Skirycz Lab combines biochemical assays, mass spectrometry, and computational tools to study how metabolites regulate proteins, impacting plant growth, stress responses, and photosynthetic efficiency. Projects often involve multi-omics approaches and translational applications in agriculture.
