معرفی
Dr Alan Richardson is a Reader in Pharmacology at Keele University, leading the Cancer Research Group and contributing to pharmacology teaching in the School of Allied Health Professions and Pharmacy. His work bridges academic research, industry experience, and innovative educational tools like KUiz and the 3D Keele KAVE environment.
- Education:PhD and postdoctoral training in pharmacology at the University of Cambridge, followed by postdoctoral work at the University of Virginia, USA.
- Industry Experience:Leadership roles in drug discovery programs at Johnson & Johnson (Belgium) and OSI Pharmaceuticals (Oxford).
- Research Focus:Targeted therapies for ovarian cancer, autophagy modulation, and overcoming chemotherapy resistance through mechanisms like statin-based treatments and autotaxin inhibition.
- Grants:Funding from the Medical Research Council, Wellcome Trust, Iraqi Higher Council for Education Development, and Keele University.
- Collaborators:Steve Allin (Charnwood Molecular), Clare Hoskins, Darren Moss, Melissa Mather (Keele), Johannes Reynisson (Auckland), Farhat Khanim (Birmingham).
- Outreach:Founded the website Why Do Scientists Do What Scientists Do for public science engagement.
His research spans mevalonate pathway inhibition, autophagy assays, and RNAi screens to identify drug resistance genes, with recent work on SARS-CoV-2 drug repurposing. Publications highlight collaborations on thymoquinone analogues, ATG5-ATG16L1 complex inhibitors, and nano-luciferase assays. Current efforts include optimizing autophagy inhibitors for clinical trials and exploring diet-drug interactions to enhance statin efficacy in cancer treatment.
Scientific Awards: Not explicitly mentioned in the text.
Grants: Funded by Medical Research Council, Wellcome Trust, Higher Council for Education Development in Iraq, Ministry of Higher Education and Scientific Research (Iraq), Keele University, and the North Staffordshire Medical Institute.
Labs & Teams: Leads the Cancer Research Group at Keele University, focusing on molecular pharmacology and translational research. Collaborates with the Keele KAVE team for virtual teaching and external institutions on drug discovery projects.
