Ahad M. Siddiqui

Ahad M. Siddiqui, Ph.D., is an Assistant Professor in the Department of Neurology and the Department of Regenerative Medicine at Mayo Clinic in Rochester, Minnesota. He holds administrative appointments as Associate Consultant I-Research in both the Department of Neurology and the Department of Physical Medicine & Rehabilitation. His interdisciplinary work bridges neuroscience, regenerative medicine, and biomedical engineering.

His research focuses on regenerative neuroimmunology, particularly in the context of spinal cord injury (SCI). Dr. Siddiqui's laboratory investigates combinatorial therapies that modulate inflammation, deliver neurotrophic factors via biomaterials, and enhance neural regeneration and functional recovery. He also pioneers the application of machine learning and AI to automate and improve the reliability of histological data analysis in neuroscience.

The recent publications of Dr. Siddiqui reflect a strong trajectory in SCI research, with emphasis on hydrogel scaffolds, microglia modulation, retinal ganglion cell survival, and AI-driven image analysis. His work integrates biomaterials, cell and gene therapies, and neuromodulation to target multiple aspects of SCI pathophysiology.

His scientific contributions have been recognized through a pilot award from the RNA Discovery and Translation Program at Mayo Clinic (2025–2026) and leadership in the Early Career Advisory Committee of the North American Spine Society (2022–present).

Dr. Siddiqui mentors research teams and collaborates across institutions, advancing translational solutions for unmet needs in neuroregeneration. His lab is actively developing novel technologies—including gene therapies, engineered cell systems, and smart biomaterials—aimed at improving outcomes for patients with neurological injuries.