Adrien Depeursinge

Adrien Depeursinge is a Professor at HES-SO Valais-Wallis - Haute Ecole de Gestion, affiliated with the School of Economics and Services and the Management Information Systems department. His research focuses on radiomics, personalized medicine via image-based analysis, and clinical workflow optimization. He leads the development of the QuantImage platform, a physician-centered web-based tool for radiomics research, and contributes to radiomics standardization efforts through initiatives like the Image Biomarker Standardization Initiative (IBSI). His work emphasizes machine learning applications in healthcare, including tumor segmentation, biomarker extraction, and improving diagnostic accuracy through computational models.

Key research themes include: 1) Radiomics – developing quantitative imaging features for cancer diagnosis/prognosis; 2) Medical Imaging Analysis – advancing texture-based models, multi-modal fusion, and automated lesion detection; 3) Physician-AI Collaboration – designing user-centric tools for clinical integration. His contributions span neuro-oncology (brain metastases), head-and-neck cancer, and multiple sclerosis imaging.

Publications emphasize methodological advancements (e.g., kernel optimization in CNNs, steerable detectors) and clinical validation (e.g., reproducibility of radiomics features across imaging protocols). He collaborates with institutions like the University Hospital of Lausanne (CHUV) and international teams on projects like the HECKTOR challenge for PET/CT tumor segmentation. His work bridges technical innovation with clinical impact, aiming to translate radiomics into actionable clinical tools.

QuantImage v2, his flagship tool, enables no-code development of machine learning models using clinical imaging data. Research also includes phantom-based validation of radiomics features and addressing challenges in feature stability across imaging modalities. Current projects explore improving contour quality for radiomics studies and optimizing AI explainability in medical decision-making.