Adam Zweifach

Adam Zweifach is a Professor in the Department of Molecular and Cell Biology at the University of Connecticut, specializing in Cell and Developmental Biology. His primary affiliation is with the College of Liberal Arts and Sciences. He holds a Ph.D. from Yale University and completed postdoctoral training at Stanford University.

Zweifach’s research focuses on T lymphocyte function, particularly signal transduction mechanisms and the role of calcium signaling in cytotoxic T cell lytic granule exocytosis. His work integrates immunology, cell biology, and pharmacology to explore therapeutic strategies for cancer and immune-related disorders.

Recent publications highlight his contributions to immunomodulatory drug discovery, high-throughput screening methodologies, and the development of genetically encoded sensors for cellular processes. His lab employs advanced techniques such as FRET-based assays and compound ensemble strategies to validate drug targets and identify novel therapeutic candidates.

Zweifach’s articles emphasize the interplay between calcium signaling pathways and T cell effector functions, with notable work on the mechanisms of cytotoxic T lymphocyte exocytosis. He has also addressed statistical rigor in experimental design, advocating for best practices in data analysis.

While no specific awards are listed, his extensive publication record reflects sustained contributions to immunology and drug discovery. His research has practical implications for developing targeted therapies and improving screening protocols in biomedical research.