Aaron Wolfe

Aaron Wolfe is an affiliated faculty member at Syracuse University and serves as Chief Science Officer at Ichor Therapeutics, Inc. His primary academic affiliation is with the College of Arts & Sciences. He holds a PhD in Structural Biology, Biochemistry, and Biophysics from Syracuse University (2011–2018), an Entrepreneurship Certificate from the Wharton School of the University of Pennsylvania (2008–2010), and a B.S. in Biotechnology (cum laude) from SUNY Environmental College of Science and Forestry (2004–2006).

Wolfe’s research focuses on membrane protein stabilization, detergent interactions, nanopore technology, and their applications in aging studies and therapeutic development. He explores mechanisms of protein-detergent complex formation, toxicity of nanomaterials, and protein engineering for drug delivery. His work bridges biophysics, biochemistry, and translational medicine, with notable contributions to understanding DNA repair in long-lived species and enzyme-based treatments for ocular diseases.

His recent publications emphasize quantitative analysis of membrane protein interactions, with studies published in Cell, GeroScience, and Journal of Physical Chemistry B. Though no formal awards are listed, his research demonstrates significant impact in structural biology and drug development.

Wolfe’s professional activities include leadership at Ichor Therapeutics, where he applies his expertise in biophysical methods and protein engineering to advance therapeutic solutions. His work integrates academic research with industry-driven applications, reflecting his entrepreneurial background from the Wharton program.