Find Academic Supervisors

• Biochemistry
• Protein Chemistry
• Enzymology
• +3 more

Dr. Adriana Firooznia serves as a Lecturer in the Department of Chemistry and Physics at The Dorothy and George Hennings College of Science, Mathematics and Technology, Kean University. Her teaching portfolio spans foundational to advanced coursework including Biochemistry, Organic Chemistry, and General Chemistry lecture-laboratory sequences. Her academic credentials: Ph.D. in Biochemistry M.S. in Chemistry Dr. Firooznia's research expertise centers on protein biochemistry with dual emphases: structural enzymology (particularly glucoamylases) and molecular mechanisms of cellular processes (meiosis, spermiogenesis). Her work integrates protein engineering, structural analysis, and functional studies to explore chromosome dynamics, RNA regulation, and enzyme-substrate interactions. This interdisciplinary approach bridges fundamental biochemical principles with applications in reproductive biology and industrial biotechnology. Publication analysis (1996-2009) reveals an evolutionary trajectory from recombinant protein production and structural characterization toward complex biological systems. Early work established methodologies for enzyme expression and structural analysis, while later studies investigated protein functions in meiosis and spermatogenesis. This progression demonstrates increasing biological complexity in her research focus, consistently leveraging international collaborations across European institutions. Scientific recognition: No major awards or fellowships documented Her teaching-centered role emphasizes laboratory-based learning across eight undergraduate courses. While no dedicated research lab exists, course-integrated laboratories provide hands-on biochemistry training. She mentors students through laboratory instruction and potential independent studies, prioritizing development of analytical skills applicable to health, environmental, and medical challenges as articulated in her teaching philosophy. Research infrastructure utilizes departmental teaching laboratories rather than a dedicated research facility. Collaborative networks established through past publications may facilitate specialized student projects, though current research activity appears secondary to pedagogical responsibilities.

• DNA Repair
• Genome Stability
• Cancer Biology
• +2 more

Daniel Gómez Cabello is an Associate Professor in the Cell Biology Department at the University of Seville, Spain, leading the Gene Expression in Eukaryotes research group. His work focuses on DNA repair mechanisms and genome stability with direct implications for cancer therapeutics. Research centers on double-strand break repair pathway choice , ribosomal DNA stress responses in tumor cells, and microRNA regulation in cellular senescence. Key investigations include: Molecular mechanisms of DNA end resection (CtIP, KLF4, PRMT5) Nucleolar stress responses under genotoxic conditions Therapeutic targeting of repair pathways (RAD52 inhibitors) Metabolic pathways in HER2+ breast cancer Recent publications (2020-2023) demonstrate strong continuity in DNA repair research, with increasing focus on therapeutic applications. The 2020 DNA Repair paper on KLF4 methylation exemplifies mechanistic work directly informing cancer treatment strategies. Active research funding includes: CNS2023-143939: Combination therapy with RAD52/RNAPII inhibitors for cancer radiosensitization INVES20017GÓME: Genome integrity in ribosomal DNA under stress PRYES235086GOME: Repairosome as radio-biomarker in radioimmunotherapy The lab maintains international collaborations through EU FP7 projects and global conference participation. The Gene Expression in Eukaryotes group combines molecular biology, genome-wide screening, and cancer cell models to investigate fundamental repair mechanisms with translational applications in oncology.

• Chromosomal Instability
• Cancer Biology
• Genome Evolution
• +4 more

Valentine Rosine Francoise Comaills is a Research Fellow leading the Cellular Plasticity and Diseases research group in the Department of Cell Biology at the University of Seville. She currently directs two major research projects: 'Origin of chromosomal instability in inflammation-induced pancreatic cancer' (PRDSE258807MEND) and 'Chromosomal instability during the Epithelium-Mesenchyme Transition' (PID2022-136786OA-I00). Her research program centers on chromosomal instability as a driver of cancer evolution, with investigations spanning nuclear envelope integrity, DNA damage response, and epithelial-to-mesenchymal transition mechanisms. She examines how these processes contribute to breast and pancreatic cancer progression, metastasis, and therapeutic resistance through molecular and genomic approaches. Her work bridges fundamental genome biology with clinical cancer applications. Dr. Comaills maintains an active publication record in high-impact journals including Science, Nature Communications, and PNAS. Analysis of her recent publications (2020-2025) reveals consistent thematic focus on chromosomal instability mechanisms, with increasing emphasis on therapeutic implications and evolutionary perspectives in cancer genomics. Her interdisciplinary work connects molecular cell biology with evolutionary theory. Her current research funding includes: R&D&I Project: Origin of chromosomal instability in inflammation-induced pancreatic cancer (PRDSE258807MEND) Chromosomal instability during the Epithelium-Mesenchyme Transition (PID2022-136786OA-I00) The Cellular Plasticity and Diseases research group operates at the intersection of cancer biology and genome evolution, utilizing advanced molecular techniques to investigate how chromosomal instability arises during cellular plasticity events and drives disease progression. The group's work has significant implications for understanding cancer heterogeneity and developing novel therapeutic strategies.

Hans-Peter LenhofView profile

Professor

• Bioinformatics
• Cancer Biology
• Personalized Cancer Therapy
• +4 more

Prof. Dr. Hans-Peter Lenhof holds the Chair for Bioinformatics at Saarland University since 2000, where he leads research in computational biology and disease mechanism analysis. His career includes: Postdoctoral research at Max Planck Institute for Informatics (1993-1999) Research Group Leader at MPI (1999-2000) Professor at Saarland University (2000-Present) His group develops innovative bioinformatics methods with three primary focus areas: Personalized Cancer Therapy : Creating AI/ML approaches to optimize drug selection from over 200 cancer therapeutics, addressing tumor heterogeneity through predictive modeling of treatment efficacy. Diagnosis & Prognosis : Pioneering blood-based diagnostic methods using autoantibody and miRNA profiles that demonstrate high clinical sensitivity for multiple cancers and neurological disorders through collaborative studies. Pathogenic Mechanism Analysis : Employing graph-based network models to visualize and analyze deregulated biological processes, particularly signaling cascades in cancer progression. The lab maintains active collaborations with Andreas Keller's Clinical Bioinformatics group and Eckart Meese's Human Genetics team. Computational tools developed include BALLView for molecular visualization, GeneTrail for high-throughput data analysis, and specialized frameworks for therapy optimization (MERIDA) and miRNA networks (miRTargetLink).

Mirna Alejandra González-GonzálezView profile

Assistant Professor

• Biotechnology
• Aqueous Two-Phase Systems
• Biomarker Detection
• +6 more

Mirna Alejandra González-González is an Assistant Professor in the Department of Chemical Engineering at Tecnológico de Monterrey's School of Engineering and Sciences, where she leads research at the Institute for Obesity Research. Her work bridges chemical engineering principles with biomedical applications, focusing on innovative diagnostic and therapeutic approaches. Her educational background includes: Chemical Engineering degree from Tecnológico de Monterrey (2008) PhD in Engineering Sciences with Biotechnology specialization from Tecnológico de Monterrey (2013) González-González's research spans multiple interdisciplinary fields with a strong emphasis on developing novel diagnostic platforms and separation techniques. Her primary research interests include aqueous two-phase systems for biomolecule separation, enzyme-based colorimetric detection of biomarkers, stem cell culture techniques, and disease-specific research in diabetes, Parkinson's disease, and vascular tumors. She has made significant contributions to adapting separation technologies for biomedical applications, particularly in non-invasive diagnostic methods using alternative biofluids like saliva. Her publication record shows consistent growth in high-impact journals, with a clear trajectory toward increasingly complex biomedical applications of chemical engineering principles. Recent work demonstrates expansion into clinical applications of her separation technologies, with growing emphasis on disease-specific research in Latin American populations. Her scientific recognition includes: Premio Mujer TEC 2016 in Science and Technology category Mexican Researcher Certification - Level 1 Multiple awards for innovation and patent generation Recognition from the Red de Oficinas de Transferencia de Tecnología (2019) As an educator, González-González supervises doctoral research and teaches advanced courses including Doctoral Research I, Doctoral Research Proposal III, and Translational Research Project. Her teaching focuses on bridging fundamental engineering principles with practical biomedical applications. She has received recognition for her publications with high indexing levels and has been honored for thesis supervision excellence. Her research group operates at the intersection of chemical engineering and biomedical sciences, with particular strength in aqueous two-phase system applications for cell culture and biomarker detection. The team maintains active connections with clinical researchers studying Parkinson's disease, diabetes, and vascular conditions, facilitating translational research pathways.

Emanuela GussoniView profile

Associate Professor

• Muscle Stem Cells
• Muscular Dystrophy
• Regenerative Medicine
• +3 more

Emanuela Gussoni is an Associate Professor in the Division of Genetics and Genomics at Harvard Medical School, with her laboratory based at Boston Children's Hospital. She leads the Gussoni Laboratory, which is part of the Intellectual and Developmental Disabilities Research Center and Research Genetics and Genomics Research units at Boston Children's Hospital. Her work bridges basic science and clinical applications in the field of muscular dystrophy and muscle stem cell biology. Dr. Gussoni earned her PhD from the University of Milan, Italy, followed by postdoctoral training at Stanford University and Boston Children's Hospital. Her research career has focused on muscle stem cells and their potential for treating muscular dystrophy. Her laboratory investigates muscle stem cells in human and mouse tissues with the translational goal of developing cell-based strategies to enhance regeneration or slow the progression of muscular dystrophy. A primary focus is understanding the function of tetraspanin CD82 in muscle stem cells, which serves as an excellent prospective marker for myogenic cells. Her team also discovers new antigens expressed by muscle stem cells and studies their role in normal and diseased tissue. Her work has led to important discoveries about bipotent progenitors in skeletal muscle that can adopt either muscle or fat lineages, and proteins that mediate fusion of myoblasts into myofibers. Analysis of Dr. Gussoni's recent publications reveals a strong focus on muscle stem cell biology, with particular emphasis on CD82 as a marker for muscle satellite cells and its role in muscular dystrophies. Her work spans basic molecular mechanisms of muscle development and regeneration to translational applications for muscular dystrophy. Over the past decade, her research has evolved from characterizing muscle stem cell properties to developing potential therapeutic strategies, including cell-based therapies and understanding the molecular pathways that could be targeted for treatment. Harvard-BBS mentorship award for mentoring graduate students (2017) Permanent member of Muscular Dystrophy Association (USA) Scientific Advisory Committee (2006-2017) Dr. Gussoni has mentored numerous graduate students and postdoctoral fellows in her laboratory at Boston Children's Hospital. Her work has been supported by various grants focused on muscular dystrophy research and muscle stem cell biology. She has also contributed to the field through service on the Muscular Dystrophy Association Scientific Advisory Committee for over a decade. The Gussoni Laboratory consists of researchers working on various aspects of muscle stem cell biology, including molecular characterization of muscle progenitors, development of methods for isolating and expanding muscle stem cells, and testing cell-based therapies in animal models of muscular dystrophy. The lab collaborates with clinicians at Boston Children's Hospital through the Roya Kabuki Program, of which Dr. Gussoni serves as co-director, connecting basic research with clinical applications.

• Molecular Biology
• Neuroscience
• RNA Biology
• +2 more

Ezgi Hacisuleyman serves as an Assistant Professor in the Department of Molecular Medicine at the University of Florida, where she leads the Hacisuleyman Lab focused on RNA-centric mechanisms in neuronal communication and cellular adaptation. Her research bridges molecular biology, neuroscience, and virology with significant contributions to understanding RNA localization, translation dynamics, and viral pathogenesis. Education Ph.D. in Molecular Biology and Biochemistry, Harvard University (2010-2015) Bachelor of Engineering in Chemical Engineering, MIT (2006-2010) Bachelor of Science in Molecular Biology and Genetics, MIT (2006-2010) Dr. Hacisuleyman's research centers on RNA biology in neuronal contexts , particularly how localized translation regulates synaptic plasticity. Her lab pioneered proximity-based ribosome profiling to map dendritic translation mechanisms, revealing how eIF4G2-uORF interactions rapidly reprogram protein synthesis in response to neuronal activity. Additional work explores lncRNA-mediated genome organization and viral-host interactions, notably SARS-CoV-2 transmission dynamics and vaccine efficacy. Her interdisciplinary approach integrates molecular techniques with computational analysis to uncover fundamental principles of RNA regulation in health and disease. Her publication portfolio shows consistent focus on RNA-centric mechanisms across cancer biology, neurodevelopment, and virology. Early work established foundational knowledge of lncRNA functions in genome architecture (Firre locus) and adipogenesis, while recent studies reveal novel cancer dependencies (EXOSC2) and neuronal translation control. The SARS-CoV-2 research during 2021 represents a strategic pivot to address urgent pandemic challenges, demonstrating methodological versatility. Scientific Awards Kavli Neuroscience Postdoctoral Fellowship (2021-2023) Helen Hay Whitney Fellowship (2016-2019) Dr. Hacisuleyman mentors graduate students including Madison Jones (neurological disorders focus) and Ulas Kaplan (5'UTR peptide research), while previously supervising SURF undergraduates. Her active NIH/NIGMS-funded grant "Decoding RNA Localization and Local Translation" supports investigations into cellular adaptation mechanisms. The lab maintains collaborations with Rockefeller University and UCSF, building on her postdoctoral work with Darnell and Weissman. The Hacisuleyman Lab comprises graduate students, research technicians (including Alexander Valera studying synaptic transmission and Alperen Baran exploring immune-neural connections), and administrative support. Current projects examine small peptide functions in neurons and RNA dysregulation in aging-related pathologies, with infrastructure for advanced molecular profiling and neuronal imaging.