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Guoyao WuView profile

Professor

• Animal Nutrition
• Protein and Amino Acid Metabolism
• Nutritional Biochemistry
• +5 more

Guoyao Wu is a Distinguished Professor of Animal Nutrition at Texas A&M University's College of Agriculture & Life Sciences, holding dual appointments in the Department of Animal Science and the Graduate Faculty of Nutrition. His expertise spans nutritional biochemistry, protein metabolism, and reproductive physiology. Dr. Wu earned his B.Sc. from South China Agricultural University, M.Sc. degrees from Beijing Agricultural University and the University of Alberta, and a Ph.D. from the University of Alberta, followed by postdoctoral training at McGill University and Memorial University of Newfoundland. His research focuses on amino acid and protein metabolism across molecular, cellular, and whole-animal levels, using models like cattle, pigs, and aquatic species. Key areas include placental nutrient transport, fetal programming, and the role of amino acids in mitigating conditions like sarcopenia and intrauterine growth restriction. He has pioneered studies on glycine, creatine, and citrulline supplementation in livestock and aquaculture. Dr. Wu has received over 15 prestigious awards from China, Canada, and the U.S., including the Thousand-People-Talent Award and Changjiang Scholar Award. He serves on editorial boards of journals like Amino Acids and Frontiers in Bioscience , and teaches graduate courses in protein metabolism. His work bridges basic science and applied nutrition, with implications for improving livestock productivity, human health, and aquaculture sustainability. Current projects address amino acid requirements of companion animals, microgravity effects on metabolism, and placental biology in ruminants.

Michael WilczekView profile

Teaching Professor

• Virology
• Bioinformatics
• Molecular Epidemiology
• +3 more

Dr. Michael Wilczek is Assistant Teaching Professor in Biotechnology/Bioinformatics at Northeastern University's Roux Institute. His research bridges virology, bioinformatics, and educational innovation, with particular focus on JC polyomavirus pathogenesis and graduate education reform. Key research domains include: Molecular mechanisms of viral infections Bioinformatic analysis of host-pathogen interactions Observational health and real-world evidence Evidence-based graduate education His publication record demonstrates: Expertise in JC polyomavirus cellular pathways Innovative applications of machine learning in virology High-throughput drug screening methodologies Health disparities research in aging populations

Sungkwon ParkView profile

Professor

• Livestock production & optimization
• Meat processing: healthy & functionality
• Establishment of environmentally friendly animal production
• +6 more

Sungkwon Park is a Professor in the Department of Food Science and Biotechnology at Sejong University, specializing in advanced food science and biotechnology research with a focus on meat science, cultured meat production, and sustainable food systems. His research integrates molecular biology, food biotechnology, and systems biology to develop innovative food solutions. His educational background includes a Ph.D. from Purdue University (2008), M.S. from Yeungnam University (2001), and B.S. from Yeungnam University (1999). Prior to his current position, he worked as a Postdoctoral Fellow at Virginia Tech (2008-2012) and as a Research Officer at the National Institute of Animal Science, RDA (2012-2015). Professor Park's research interests focus on livestock production optimization, meat processing for health functionality, environmentally friendly animal production systems, and in vitro meat production. His work has led to significant achievements including the identification of calcium and glucose interaction mechanisms in muscle metabolism, development of oleogel-based meat processing techniques, optimization of feed ingredients for sustainable livestock, and establishment of in vitro meat production systems. His recent publications (2023-2025) demonstrate a strong focus on cultured meat technology, meat science, and sustainable food production. The research spans cellular mechanisms for cultured meat production, safety and regulatory aspects of alternative proteins, comparative analysis of muscle satellite cells, and optimization of meat processing techniques. His work shows a clear trend toward developing practical applications for next-generation meat products with emphasis on health functionality and environmental sustainability. Professor Park actively serves as a reviewer for Frontiers in Veterinary Science and is an Editorial Board Member of the Korean Society of Animal Science. His laboratory, the M&M'a lab (Functional Food Lab), conducts research on high-value-added, health-functional BioFood and future foods using bio-convergence technologies.

John A. Copland, IIIView profile

Professor

• Cancer Biology
• Molecular Carcinogenesis
• Translational Research
• +3 more

Dr. John A. Copland III is a Professor of Cancer Biology and Biochemistry & Molecular Biology at Mayo Clinic in Jacksonville, Florida. He leads the Cancer Biology and Translational Research Laboratory, focusing on molecular mechanisms of carcinogenesis, tumor progression, and development of targeted cancer therapies. Education: PhD in Physiology & Endocrinology (Medical College of Georgia), MS in Endocrinology (Medical College of Georgia), BS in Chemistry (Columbus College), with postdoctoral training at University of Texas Medical Branch. Research interests center on: Identifying tumor suppressor genes (e.g., RhoB, TBR3, GATA3) and oncogenes (e.g., FOXO3a, SCD1, NPTX2). Developing patient-derived xenografts and live cell models for personalized medicine. Designing SCD1 inhibitors via in silico modeling for clinical trials. Recent publications highlight his work on SCD1 inhibition in leukemia and thyroid cancer ImmunoPET imaging of thyroid tumors CRISPR-identified drug synergies in cholangiocarcinoma Patient-specific combination therapies using xenograft models

• Statistical Methods in Biomedical Research
• Biomarker Analysis
• Clinical Trial Design
• +7 more

Todd A. Alonzo is a Professor of Research in the Department of Preventive Medicine at the University of Southern California . As Group Statistician for the Children's Oncology Group , he focuses on statistical methods for biomarker analysis, medical diagnostic testing, and clinical trial design in pediatric acute myeloid leukemia (AML). Education: B.S. in Statistics, California State Polytechnic University (1994) MS and PhD in Biostatistics, University of Washington (1997, 2000) Research Interests include: Development of statistical frameworks for diagnostic accuracy Genomic and proteomic profiling in AML Pharmacogenomic score systems for chemotherapy response Non-inferiority trial design in low-event-rate settings Health disparities in pediatric oncology Scientific Awards : Fellow, American Statistical Association (2018) Outstanding Teacher Award, International Society for Magnetic Resonance in Medicine (2017) NIH Predoctoral Cardiovascular Biostatistics Training Grant (1995) ENAR Biometrics Society Distinguished Student Paper Award (1999) WNAR Biometrics Society Best Student Oral Presentation (1999) Leadership & Service includes editorial board memberships (Biometrics, Pediatric Blood & Cancer, Biometrical Journal), reviewer for 30+ scientific journals, and roles on multiple Data Safety and Monitoring Boards. He served as President of the International Biometric Society Western Northern America Region (WNAR) in 2009.

• Skeletal Muscle Growth
• Ribosome Biogenesis
• Exercise Physiology
• +4 more

Gustavo Nader, Ph.D., is a Professor of Kinesiology at The Pennsylvania State University's College of Health and Human Development, where he holds the Dorothy Foehr Huck and J. Loyd Huck Endowed Chair in Molecular, Cellular and Integrative Physiology. His research laboratory at 101 Noll Lab focuses on molecular mechanisms of skeletal muscle adaptation, employing human, animal, and cellular models to investigate ribosome biogenesis, transcriptional regulation, and muscle growth control in contexts ranging from exercise hypertrophy to cancer cachexia. Dr. Nader's research examines fundamental processes including: Ribosome biogenesis and its role in muscle growth regulation Epigenetic control of RNA Polymerase I activity Molecular pathways in mechanical overload-induced hypertrophy Tumor-induced muscle wasting mechanisms Biomimicry approaches inspired by hibernator physiology His work spans exercise physiology, cancer biology, and environmental stress responses. Analysis of his 15 most recent publications (2015-2025) reveals predominant themes in muscle hypertrophy mechanisms, cancer cachexia pathophysiology, ribosomal function analysis, and environmental stress impacts on muscle. His work consistently integrates molecular techniques with physiological models across species. Notable scientific recognitions include: Dorothy Foehr Huck and J. Loyd Huck Chair appointment (2024) Huck Institutes Leadership Fellowship (2025-2026) Dr. Nader leads an active research team investigating muscle plasticity, with current projects funded through the Huck Institutes of the Life Sciences. He collaborates extensively through Penn State's Integrative and Biomedical Physiology graduate program and Center for Cellular Dynamics.

• Neuroscience
• Psychiatry
• Neurotransmitter Modulation
• +5 more

Philip Burnet is a Professor of Neuroscience at the University of Oxford, affiliated with the Department of Psychiatry . He serves as the Director of Graduate Studies for Psychiatry , teaches on the MSc Neuroscience and MRCPsych courses, and sits on the editorial board of Nutrition and Aging . His research bridges neuroscience and psychiatry, focusing on neurotransmitter modulation and brain health. Research interests: Burnet investigates the regulation of serotonin and glutamic acid systems in aging and psychiatric disorders. Key projects include exploring D-amino acid oxidase (DAO) inhibition to restore cognition in schizophrenia, analyzing the microbiome-gut-brain axis , and testing dietary interventions like probiotics and ketogenic diets for mental health applications. His work combines molecular techniques with behavioral studies in preclinical and clinical contexts. Article trends reveal a focus on neurotransmitter dynamics , microbiome-brain interactions , and metabolic interventions . Notable methods include RNA interference , animal models , and clinical trial protocols . Professional activities: Collaborates across Oxford and with industry partners, contributes to academic editing, and engages in graduate education leadership.

Prashant MaliView profile

Professor

• Genome Engineering
• RNA Editing
• Stem Cell Research
• +4 more

Prashant Mali is a Professor in the Department of Bioengineering at the University of California, San Diego . His research bridges genome engineering, RNA biology, and biomedical applications, with a focus on CRISPR-Cas systems and ADAR-mediated RNA editing. Education : Ph.D. in Bioengineering Key Affiliations : UC San Diego, Altman Clinical and Translational Research Institute Dr. Mali's work centers on CRISPR-Cas9 technology , RNA editing , and human pluripotent stem cells . His lab develops tools for programmable gene regulation, synthetic lethal screens, and metabolic pathway analysis in disease contexts. Recent publications highlight innovations in circular RNA engineering , ADAR activity mapping , and metabolic reprogramming in cancer . His team employs multi-omics approaches and in vivo models to translate genome editing into clinical applications. Students and Collaborators Current Lab Members : Sami Nourreddine (Postdoc), Amir Dailamy (Graduate), Andrew Portell (Graduate), Michael Tong (Graduate) Alumni : Kyle Ford (PhD 2022), Nathan Palmer (PhD 2022), Udit Parekh (PhD 2021) Research Themes CRISPR Screens : Synthetic lethal interactions, oncogenic pathways, metabolic vulnerabilities RNA Editing : ADAR engineering, circular guide RNAs, clinical translation Tissue Engineering : Vascularized organoids, cardiac maturation, ex vivo models

• Sports Science
• Molecular Biology
• Exercise Physiology
• +3 more

Vignesh Ram Somnath is a Professor in the Biosciences of Sports at the University of Hildesheim since 2018. Previously, he served as an Acting Professor (2016-2018) and Research Associate (2010-2016) at the Institute of Sports Science, German Sports School Cologne. His work bridges molecular biology with sports science, focusing on skeletal muscle adaptation. Current: University Professor W2, University of Hildesheim 2016-2018: Acting Professor, University of Hildesheim 2010-2016: Research Associate, German Sports School Cologne 2005-2007: Research Assistant, German Sports School Cologne Research Interests: Regulation of molecular signaling pathways in skeletal muscle Mechanoprotective mechanisms during exercise Protein degradation dynamics Optimization of training and nutrition in competitive sports Integration of molecular biology with traditional sports science Key Publications (2020-2017) demonstrate expertise in: Metabolomics of muscle hypertrophy AMPK signaling in training Mitochondrial adaptations Extracellular vesicle analysis Calcium signaling pathways

Heather MurrayView profile

Lecturer

• Proteomics
• Phosphoproteomics
• Acute Myeloid Leukemia (AML)
• +3 more

Dr. Heather Murray is a Cancer Institute NSW Early Career Research Fellow at the University of Newcastle, affiliated with the School of Biomedical Sciences and Pharmacy. She holds dual roles as a Lecturer and Postdoctoral Researcher, focusing on proteomics and phosphoproteomics to uncover therapeutic targets in acute myeloid leukemia (AML). Her work combines genomic, proteomic, and clinical approaches to address treatment resistance and precision medicine in blood cancers. Education: PhD in Medical Biochemistry (University of Newcastle, 2020), MPhil, BSc (Hons) in Biomedical Sciences, and BSc in Biological Sciences, all from the University of Newcastle. Research Interests: Proteomic characterization of leukemia subtypes, DNA repair mechanisms, and drug resistance pathways. Her lab uses phosphoproteomics to identify synergistic drug combinations targeting oncogenic pathways like FLT3 and KIT mutations. Key Collaborations: Works with clinicians like Associate Professor Anoop Enjeti and researchers at Hunter Medical Research Institute. Partnerships include institutions like the University of Southern Denmark and QIMR Berghofer. Grants & Funding: Secured over $2M in funding, including a 2022 Cancer Institute NSW Fellowship, BarbeCURE grants, and philanthropic support from organizations like the McDonald Jones Charitable Foundation. Supervision: Mentors 6 current PhD students on topics like venetoclax resistance, breast cancer biomarkers, and ex vivo AML models. Supervision history includes 6 completed Honours projects. Labs/Teams: Leads the Molecular Oncology group under Associate Professor Nikki Verrills. Member of the HMRI Precision Medicine Program and University of Newcastle ECR committees.

David WalkerView profile

Professor

• Aging
• Mitochondrial Biology
• Neurodegeneration
• +3 more

David Walker is a Professor and Vice Chair of Academic Personnel in the Department of Integrative Biology and Physiology at the University of California, Los Angeles. He leads a research lab focused on understanding the molecular and cellular basis of aging, utilizing Drosophila melanogaster to investigate mechanisms such as mitochondrial dysfunction, autophagy, and intestinal barrier integrity. His work aims to identify therapeutic targets for age-related diseases. Education: B.S., Genetics, Queen's University Belfast (1995) MRes, Molecular Biology, University of Manchester (1996) Ph.D., Genetics, University of Manchester (2000) Walker's research interests center on the biological processes driving aging, with emphasis on mitochondrial dynamics, neurodegeneration, and gut-microbiota interactions. His lab employs genetic, molecular, and physiological approaches in Drosophila to dissect how cellular deterioration impacts lifespan and healthspan, bridging insights to human aging pathologies. Key themes include the role of autophagy adaptors (e.g., p62/SQSTM1), mitochondrial fission, and intestinal homeostasis in longevity. His recent publications (2014–2024) reveal a consistent focus on brain aging, mitophagy, and gut-brain axis disruptions, with trends toward identifying midlife interventions for healthspan extension. Articles frequently integrate cellular stress responses, metabolic regulation, and neurodegeneration, highlighting Drosophila as a versatile model for translational aging research. No scientific awards, prizes, or fellowships are mentioned in the provided text. While specific grants or student advisees are not detailed, Walker's lab actively mentors researchers and contributes to collaborative projects on aging mechanisms. Future directions may involve exploring mitochondrial-immune interactions and novel longevity pathways. Walker directs a Drosophila-focused laboratory at UCLA, emphasizing genetic screens and mechanistic studies to uncover evolutionarily conserved aging pathways. The team investigates tissue-specific aging cascades, including neuronal and intestinal systems, to develop strategies for mitigating age-related decline.

• Genetics
• Molecular Biology
• Gene Therapy
• +4 more

Shushu Huang is an Associate Research Scientist in the Department of Genetics at Yale School of Medicine. They hold a PhD from Nanjing Medical University (2023) and an MD from the same institution (2013). Their research focuses on genetic and molecular mechanisms underlying metabolic disorders, muscular dystrophies, and cardiovascular diseases. Key areas include CRISPR-based therapeutic discovery, high-throughput functional genomics, and gene therapy safety. Huang has collaborated with researchers like Monkol Lek and Carlos Fernandez-Hernando on projects involving LXR signaling, DUX4 toxicity, and MC4R variant analysis. Publications span studies on vascular biology, gene therapy outcomes, and obesity genetics. Notable work includes investigating hypercholesterolemia’s role in vascular remodeling and analyzing MC4R variants in morbid obesity. Their lab is located in the Anlyan Center, New Haven.

• Metabolic Signaling
• Pancreatic Islet Biology
• Signal Transduction Pathways
• +4 more

Dr Amin Ardestani , Senior Lecturer in Metabolic Signaling at the Biomedical Institute for Multimorbidity (BIM), Hull York Medical School (HYMS) , specializes in unraveling molecular mechanisms of pancreatic β-cell failure in diabetes. His research program identifies novel therapeutic targets through signal transduction studies in metabolic disorders. Bachelor's in Biology, Tarbiat Moalem University (2004) Master's in Biochemistry, Institute of Biochemistry and Biophysics (2007) PhD in Biology, University of Bremen (2013) Junior Group Leader at University of Bremen (2014-2023) Research focuses on Hippo and mTOR signaling pathways in β-cell biology, autoimmunity, and regeneration. His work bridges mechanistic biology with drug discovery for diabetes, with significant findings on PHLPP1/2 phosphatases and MST1/2 kinases. Recent publications highlight therapeutic strategies for β-cell protection , including small molecule inhibitors (e.g., MST1/2 inhibitors) and metabolic enzyme modulation (LDHA). Collaborative studies explore SARS-CoV-2 interactions with pancreatic cells and cross-talk between acinar and β-cells in diabetes. 2019 JDRF Advanced Postdoctoral Fellowship 2018 Impulse grant & Career Advancement Award 2017 Early Investigators awards (Endocrine Society, EFSD/Lilly Programme) 2014 Albert Renold Fellowship & Bremer Studienpreis Professional roles include Editorial Board Member at Scientific Reports and Associate Editor at Frontiers in Endocrinology . He reviews grants for DFG, Diabetes UK, and ISF, and evaluates manuscripts for top-tier journals like Cell Metabolism and Nature Communications.

• Neuro-oncology
• Neuropathology
• Glioblastoma
• +3 more

Professor Patrick Harter is a faculty member at the Institute of Neuropathology, Ludwig Maximilian University of Munich (LMU), where he leads research in neuro-oncology and molecular diagnostics of CNS tumors. His work focuses on glioblastoma, meningioma, and brain metastasis, with emphasis on epigenetic mechanisms like DNA methylation and metabolic adaptations in the tumor microenvironment. Research interests span: Molecular classification of brain tumors using DNA methylation profiling Therapeutic targeting of BRAF/MEK and PI3K/Akt/mTOR pathways Role of hypoxia and metabolic plasticity in treatment resistance Liquid biopsy development for non-invasive tumor monitoring His recent publications demonstrate a strong trend toward integrating epigenetic, metabolic, and immunotherapeutic approaches. Articles frequently explore: Novel biomarkers for tumor grading and prognosis Mechanisms of therapy resistance in gliomas Impact of tumor microenvironment on metastasis

• Epidemiologic Factors
• Epidemiologic Methods
• Glioblastoma
• +7 more

Katsuhito Yasuno is a Research Scientist in the Department of Neurosurgery at Yale School of Medicine. He works within the Gunel Lab, focusing on neurogenetic research related to brain disorders, vascular conditions, and tumors. His work involves genomic analyses and molecular studies to understand the genetic basis of various neurological conditions. Education: Postdoctoral Fellow, Japan Science and Technology Corporation (2008) Postdoctoral Fellow, Japan Biological Informatics Consortium (2006) Postdoctoral Fellow, Tokai University School of Medicine (2004) PhD in Theoretical Physics, Tokyo Institute of Technology (2002) MS in Theoretical Physics, Tokyo Institute of Technology (1999) BS in Physics, Tokyo Metropolitan University (1997) Dr. Yasuno's research spans multiple areas of neurogenetics and molecular neuroscience. His primary interests include epidemiologic factors and methods related to brain tumors (particularly glioblastoma and meningioma), intracranial aneurysms, nervous system diseases and malformations, and vascular diseases. His physics background contributes to sophisticated analytical approaches in genetic research. His publication record shows consistent contributions to understanding the genetic mechanisms underlying neurological disorders, with recent work focusing on meningioma genetics, brain malformations, and vascular disorders. The research demonstrates a progression from basic genetic discovery to translational applications, with particular emphasis on molecular pathways that could serve as therapeutic targets. Dr. Yasuno collaborates extensively with leading researchers in the field, most notably with Dr. Murat Günel (28 common publications) and Dr. Kaya Bilguvar (34 common publications). His work involves both computational analysis and laboratory validation of genetic findings. As part of the Gunel Lab, Dr. Yasuno contributes to the lab's three major research interests: developmental neurogenetic disorders, neurovascular disorders, and brain tumor biology. The lab utilizes advanced genomics techniques and bioinformatic analysis for gene discovery followed by functional studies.