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D.S. Fahmeed HyderView profile

Professor

• Magnetic Resonance Imaging
• Neuroimaging
• Molecular Imaging
• +3 more

D.S. Fahmeed Hyder is a Professor of Biomedical Engineering at Yale University, with additional appointments in Radiology & Biomedical Imaging. He holds a Ph.D. from Yale University and leads the Hyder Lab, which focuses on advancing quantitative and translational imaging technologies using magnetic resonance methods to study brain function and dysfunction at the laminar level. His research integrates multidisciplinary approaches, including molecular imaging, neurophysiology, and material science. Research Interests: Neurovascular and neurometabolic coupling mechanisms Molecular imaging probes for disease diagnostics Functional MRI (fMRI) and metabolic imaging in health and disease Imaging applications for Alzheimer’s, stroke, and cancer Publications: Dr. Hyder’s recent work emphasizes cutting-edge imaging techniques, such as pH-sensitive biosensors, high-resolution fMRI, and multimodal optical imaging. His research highlights include studies on neurovascular dysfunction in Alzheimer’s models, therapeutic interventions for brain injury, and molecular imaging of tumor microenvironments. Awards: Niels Lassen Award (2003), for cerebral blood flow research Early Career Faculty Award (1998), NSF & NIH Pilot Awards from JDRF & Yale-UCL Collaborative (2008, 2013) Labs/Teams: The Hyder Lab collaborates with institutions like UCL and the James S. McDonnell Foundation, advancing translational imaging solutions for clinical applications.

Marios GeorgakisView profile

Researcher

• Cardiovascular Disease
• Stroke
• Atherosclerosis
• +8 more

Marios Georgakis is a clinician-scientist and Junior Group Leader at the Institute for Stroke and Dementia Research (ISD) at LMU Munich. He also holds a Visiting Scientist position at the Broad Institute of MIT and Harvard. His research focuses on leveraging multi-omics data and causal inference methods (e.g., Mendelian randomization) to discover drug targets for atherosclerosis, develop personalized risk stratification tools for cerebrovascular disease, and identify in vivo biomarkers of disease activity. His work bridges human genetics, molecular biology, and clinical translation. Education : MD and PhD (Epidemiology) from the National and Kapodistrian University of Athens; doctoral studies in Systemic Neurosciences at LMU Munich. Honors : Emmy Noether Award (DFG), CHARGE Consortium Early Career Achievement Award, Hertie Network Fellowship, and multiple scholarships/fellowships. Research Themes : Drug target discovery for cardiovascular disease via multiomics integration Molecular phenotyping of atherosclerosis using single-cell RNA-seq and spatial transcriptomics Development of AI-driven tools for vascular imaging and aging Genetic studies of inflammation, cytokines, and stroke subtypes Causal inference in vascular risk prediction and post-stroke outcomes Recent Article Trends : His team's publications (2024-2020) emphasize: Proteogenomic and genetic studies of atherosclerosis Cytokine signaling pathways (e.g., IL-6, CCL2/CCR2) Polygenic and genomic risk scores for stroke Multi-omics biomarkers in cerebrovascular disease Clinical translation of Mendelian randomization findings Meta-analyses of population-based data Scientific Awards : Emmy Noether Group Leader Award (DFG, 2023) CHARGE Consortium Early Career Achievement (2023) Hertie Network Fellowship (2023) Walter-Benjamin Postdoctoral Fellowship (2021-2022) Team Leadership : Georgakis mentors multiple PhD students and postdocs in his lab. His group collaborates with vascular surgeons, neurologists, and computational biologists. Current projects include the AtherOMICS biobank and AI-driven vascular phenotyping tools.

Umamaheswari NatarajanView profile

Researcher

• Cancer Biology
• Epigenetic Modifications in Cancer
• Drug Discovery
• +5 more

Umamaheswari Natarajan is an Associate Research Scientist at Nova Southeastern University's Rumbaugh-Goodwin Institute for Cancer Research within the Barry and Judy Silverman College of Pharmacy. She earned a Ph.D. in Pharmacy from the University of Madras, India, and holds prior degrees including a D.Pharm., M.Sc., and B.Sc. from Indian institutions. Ph.D., University of Madras, India D.Pharm., The Tamil Nadu Dr. M.G.R. Medical University, India M.Sc., Madurai Kamaraj University, India B.Sc., Madurai Kamaraj University, India Dr. Natarajan's research focuses on epigenetic modifications in cancer, particularly identifying biomarkers for tumor aggressiveness and drug resistance, and improving delivery of anti-angiogenesis drugs like F16 and JFD for brain cancers. Her work spans breast, prostate, ovarian, lung, osteosarcoma, glioblastoma, and neuroblastoma studies. She has published 14 peer-reviewed papers and co-authored numerous conference presentations. Her Google Scholar publications reveal a strong emphasis on HDAC inhibitors, MDM2/MDMX regulation, AURKB interactions, and anti-angiogenic therapies. Subfields include neuroblastoma, lung cancer, and ovarian cancer treatment resistance mechanisms. Epigenetic modifications in cancer Drug discovery Angiogenesis Cell cycle regulation Apoptosis Pharmacogenomics Dr. Natarajan actively mentors graduate and undergraduate students in research electives, guiding presentations at conferences like ABRCMC and AACR. Her students have received multiple awards for their work. She also contributes to the Honors College as a course instructor. Current projects involve enhancing brain delivery of anti-angiogenesis drugs and exploring epigenetic biomarkers across cancers. Collaborations include Appu Rathinavelu, Ph.D., in developing research electives.

Anders NykjærView profile

Professor

• Neuroscience
• Neurodegenerative Diseases
• Molecular Biology
• +3 more

Anders Nykjær is a Professor at the Department of Biomedicine , Aarhus University , and Director of the DANDRITE - Nykjær Group . His research focuses on the role of VPS10p-domain receptors, particularly sortilin and SorCS2 , in neuronal viability, neurotrophic signaling, and neurodegenerative diseases. University: Aarhus University Department: Department of Biomedicine Lab: DANDRITE - Nykjær Group Nykjær's work spans neurodegenerative diseases (Alzheimer's, Huntington's), neurotrophic factors (BDNF, NGF), and receptor biology . His studies investigate how receptors like sortilin modulate amyloid-beta catabolism, dopaminergic neuron development, and neurovascular coupling. Recent articles highlight SorCS2 in motor neuron development and progranulin interactions. Article trends include neurovascular signaling (SorCS2 in astrocytic function), neurotrophic receptor dynamics (TrkB/GluN2B/SorCS2 complexes), and cardiovascular-neurological cross-talk (sortilin in atherosclerosis and diabetic retinal degeneration). His methods involve in vivo models, proteomics, and receptor-ligand interaction studies. Scientific contributions emphasize receptor biology in Neurodegenerative disease mechanisms Lipoprotein and neurotrophin receptor trafficking Neurovascular and synaptic signaling pathways

Wenjie LuoView profile

Researcher

• Neuroscience
• Alzheimer's Disease
• Microglial Research
• +5 more

Wenjie Luo is a researcher at the Brain and Mind Research Institute, Weill Cornell Medical College, focusing on neurodegenerative diseases and neuroimmunology. His role involves investigating molecular pathways linking tauopathy, microglial function, and genetic risk factors for Alzheimer's disease. Education: B.S. and M.S. from Peking University (China), Ph.D. from Albert Einstein College of Medicine (2001) His research explores the interplay between neuroinflammatory mechanisms, tau pathology, and genetic variants in Alzheimer's disease progression. Key areas include the cGAS-STING pathway, TREM2 agonism, and microglial interactions with oligodendrocytes. Recent publications highlight his work on tau propagation models, microglial signaling pathways (NF-κB, AKT), and sex-based differences in neurodegeneration. He collaborates on grants from the National Institute on Aging and BrightFocus Foundation, focusing on tau metabolism, TREM2 ligands, and APOE mutations in neurodegenerative diseases.

Michael S. WolinView profile

Professor

• Oxidative Stress Signaling
• Pulmonary Hypertension
• Vascular Physiology
• +7 more

Michael S. Wolin, Ph.D., is a distinguished Professor of Physiology at the School of Medicine, New York Medical College (NYMC). With a career spanning several decades, Dr. Wolin has established himself as a leading researcher in vascular physiology, redox biology, and pulmonary hypertension. His work began with groundbreaking research on nitric oxide signaling as a postdoctoral fellow with Lou Ignarro at Tulane University, contributing to aspects of research that led to Ignarro's 1998 Nobel Prize in Physiology and Medicine. Dr. Wolin's research interests focus on oxidative stress signaling , pulmonary hypertension , vascular physiology , redox biology , nitric oxide signaling , and mitochondrial function . His NIH-funded laboratory at NYMC has made significant contributions to understanding how cellular regulatory systems—including mitochondrial function, oxidases, ROS metabolizing enzymes, and cellular redox control systems—function in physiological processes and pathophysiological conditions. His work has particularly advanced our understanding of oxygen sensing mechanisms, hypoxic pulmonary vasoconstriction, and the role of hydrogen peroxide as a signaling molecule. Dr. Wolin's recent publications (2019-2025) demonstrate continued research productivity with significant contributions to understanding placental development in maternal undernourishment, pulmonary vascular function, oxidative stress mechanisms in hypertension, and the role of various signaling molecules in cardiovascular disease progression. His work shows a consistent focus on the interplay between redox signaling, mitochondrial function, and vascular pathophysiology. Notable awards and honors include: Distinguished Scientist Award – American Chemical Society, Westchester Section (2010) Outstanding Faculty Award – Graduate Student Association of Basic Medical Sciences at NYMC (2009) Robert M. Berne – Distinguished Lectureship Awardee – American Physiological Society (2008) Merit Award – National Heart, Lung & Blood Institute, NIH (1995) Dr. Wolin has maintained significant editorial and service roles, including serving as Chair of the Integrative Vascular Physiology Pathology NIH Study Section (2021-2023), Consulting Editor for the American Journal of Physiology: Heart & Circulatory Physiology (2011-2018), and as a Fellow of the American Heart Association since 2001. His teaching responsibilities at NYMC include directing multiple physiology courses and mentoring graduate students through thesis research.

Kenneth A. BarbeeView profile

Professor

• Cellular Biomechanics
• Mechanotransduction
• Cardiovascular System
• +5 more

Kenneth A. Barbee is a Professor and Senior Associate Dean for Research at the School of Biomedical Engineering, Science and Health Systems at Drexel University . His research focuses on cellular biomechanics, particularly the response of neural and vascular tissues to mechanical loading and trauma. Education : PhD in Bioengineering from University of Pennsylvania (1991), MS in Bioengineering from University of Pennsylvania (1988), BS in Engineering Science and Mechanics from University of Tennessee (1986) Barbee's research explores mechanotransduction in the cardiovascular system, including how endothelial cells respond to shear stress and vascular smooth muscle cells adapt to cyclic stretching. He employs advanced techniques such as Atomic Force Microscopy (AFM) , Computational Fluid Dynamics (CFD) , and fluorescence microscopy in his work. His studies also address cellular injury criteria under traumatic loading conditions to aid protective equipment design and therapeutic evaluation. Publications highlight his contributions to understanding shear stress gradients in atherogenesis, calcium signaling in endothelial cells, and deformation models for vascular smooth muscle. These works span disciplines including biomechanics , cell biology , and bioengineering .

Li ZhangView profile

Professor

• Molecular Biology
• Cell Biology
• Genomics
• +4 more

Dr. Li Zhang is a Professor and Head of the Department of Biological Sciences at the University of Texas at Dallas (UT Dallas), holding the Cecil H. and Ida Green Distinguished Chair in Systems Biology. He has held academic positions at Columbia University, New York University, and MIT. His research focuses on heme signaling, lung cancer, Alzheimer’s disease, and molecular mechanisms of cellular metabolism. He has secured funding from CPRIT and NIH, including a CPRIT grant for optimizing therapeutic strategies against lung cancer. Education: Postdoc (MIT, 1995), Ph.D. in Biochemistry (UCLA, 1990), B.S. in Chemistry (Zhongshan University, China, 1984). Research interests include heme’s role in cancer progression, Alzheimer’s pathogenesis, and oxygen signaling. His lab has published extensively on heme regulation in tumors and neuronal systems, with key findings on heme sequestration as a therapeutic strategy. Notable publications in Cancer Research and Alzheimer's & Dementia highlight his contributions. Awards include the Cecil H. and Ida Green Chair, Monique Weill-Caulier Scholarship, and recognition as a top-cited author in molecular biology. He has co-founded a company to commercialize IP from his research on heme-based therapies.

• Vascular Biology
• Renal Physiology
• Hypertension Pathophysiology
• +3 more

Jonathan Nelson is an Assistant Professor in the Division of Nephrology & Hypertension at the University of Southern California (USC) Keck School of Medicine. He holds a PhD in Molecular and Medical Genetics from Oregon Health & Science University (OHSU), where he also completed clinical training in Anesthesiology, Cardiovascular Medicine, and Nephrology. His research focuses on vascular biology and the renin-angiotensin system's role in kidney microvasculature regulation, with funding from the NIH, American Heart Association, and Collins Medical Trust. Education: Bachelor’s degree in Biochemistry, University of Washington PhD in Molecular and Medical Genetics, Oregon Health & Science University Research interests include understanding how angiotensin II signaling impacts kidney and cardiovascular health, particularly in hypertension and microvascular dysfunction. His work bridges molecular mechanisms with clinical implications, leveraging mouse models to study renal physiology and disease pathways. Publications highlight his focus on renal transporters, endothelial signaling, and angiotensin system dynamics. Recent work explores ACE2 filtration in kidneys and COP9 signalosome roles in renal injury. Grants & Funding: NIH, American Heart Association, Collins Medical Trust. Labs/Teams: His research is conducted within the USC Keck School of Medicine’s Division of Nephrology & Hypertension, collaborating with cardiovascular and renal biology experts.

• Thrombosis
• Haematology
• Cardiovascular Medicine
• +5 more

Professor Denise Jackson is a faculty member in the Department of Health and Biomedical Sciences at RMIT University, Bundoora West campus. She serves as the Head of the Thrombosis and Vascular Biology laboratory and holds an honorary fellowship from the National Health and Medical Research Council (NHMRC). Her research focuses on thrombosis mechanisms, platelet biology, and immunoreceptor roles in infection and immunity. She coordinates courses such as MEDS1142 Medical Informatics, BUSM3220 Medical Laboratory Quality Systems, and ONPS2153 Medical Informatics and Laboratory Management. Research Interests: Professor Jackson’s work spans thrombosis, platelet function, mouse models of thrombus formation, and the molecular mechanisms of immunoreceptors in pathogens. Her team investigates tetraspanins’ role in blood clot regulation and signaling pathways in platelets. Key projects include studying tyrosine kinase inhibitors’ effects on haemostasis and exploring immunoreceptor crystal structures for drug design. Professional Involvement: She reviews grants for NHMRC, National Heart Foundation, and international bodies like the Wellcome Trust and NSF. She also serves as a reviewer for journals including Nature and Blood . Student Supervision: Principal supervisor of 12 Honours, 3 Masters, and 4 PhD students. Labs/Teams: Leads the Thrombosis and Vascular Biology lab, collaborating on drug development and thrombosis prevention strategies.

• Vascular Surgery
• Diabetic Kidney Disease
• Vascular Biology
• +3 more

Ocean Setia is a faculty member at Yale School of Medicine (Yale University), affiliated with the Dardik Laboratory for Vascular Biology and Therapeutics. He holds a medical degree (MBBS) from Sardar Patel Medical College (2016). His research focuses on vascular surgery innovations, diabetic kidney disease mechanisms, and surgical interventions for vascular pathologies. His work spans clinical studies on wound therapy, imaging techniques for vascular diagnostics, and mechanistic studies on endothelial cell biology and fibrosis. Key contributions include advancements in surgical techniques like mesenteric artery transposition and insights into sex hormone impacts on arteriovenous fistula maturation. He has published extensively in journals such as Science Advances , Journal of Vascular Surgery , and Annals of Vascular Surgery . Research interests emphasize translational applications of vascular biology, including machine learning algorithms for occlusion detection and regenerative therapies using stem cells. His articles highlight interdisciplinary approaches, combining surgical innovation with molecular mechanisms in diabetic complications. No scientific awards are explicitly mentioned, though his active publication record underscores scholarly engagement. Academically, he collaborates with clinicians and researchers like Britt Tonnessen, Jonathan Cardella, and Alan Dardik. His lab work involves preclinical models and human trials, focusing on improving outcomes for vascular diseases. No formal grants or student advisement roles are detailed in the provided texts.

• Neurocritical Care
• Vascular Neurology
• Traumatic Brain Injury
• +6 more

Dr. Gunjan Y. Parikh serves as an Associate Professor in the Department of Neurology at the University of Maryland School of Medicine, where she also functions as the Medical Director of the UMMC Neuro Critical Care Unit. Her clinical practice focuses on the intersection of neurology and critical care medicine, with particular expertise in managing patients with acute neurological emergencies including traumatic brain injury, intracerebral hemorrhage, and subarachnoid hemorrhage. Dr. Parikh completed her undergraduate education with a BA in Biochemistry from The University of Texas at Austin, followed by her MD from Texas A&M College of Medicine. Her clinical training includes an Internal Medicine internship at St. Vincent's Hospital - Manhattan, Neurology residency at Barrow Neurological Institute at Saint Joseph's Hospital and Medical Center (where she also served as Chief Resident), and specialized fellowship training in Neurocritical Care/Vascular Neurology at Columbia University Medical Center/Weill Cornell Medical Center. She further enhanced her research skills through an NINDS Research Fellowship in Neuroimaging at the National Institutes of Health. Her research program centers on identifying biomarkers during the resuscitation phase of patients with acute brain injuries that determine lesion repair, restoration of function, and recovery of consciousness. This work has led to significant contributions in characterizing the MRI signature of primary microvascular injury after head trauma and other acute brain injuries through both in vivo and ex vivo investigations. Her lab integrates multimodality monitoring with advanced neuroimaging techniques to translate findings to clinical care and develop outcome measures for clinical trials targeting currently untreatable aspects of brain injury such as demyelination and neurodegeneration. Analysis of Dr. Parikh's recent publications reveals a strong focus on translational neuroscience with emphasis on neuroimaging techniques, biomarker discovery, and clinical applications for acute brain injury management. Her work spans from basic science investigations of microvascular injury to clinical studies on patient outcomes, with particular attention to traumatic brain injury, intracerebral hemorrhage, and subarachnoid hemorrhage. Recent publications demonstrate increasing integration of data science approaches for predicting neurological deterioration and developing automated clinical assessment tools. Fellow of the Neurocritical Care Society (2024) Member, American Academy of Neurology Member, Neurocritical Care Society Member, National Neurotrauma Society Dr. Parikh serves as Site Co-PI for the DISCOVERY study (Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on Recovery) under NINDS/NIA U19 NS115388, and as SubK site-PI for the REACH-ICH study (Race/Ethnicity, Hypertension and Prevention of VCID and Stroke after Intracerebral Hemorrhage) under NINDS/NIH 5R01NS093870-08. Her research has been featured in multiple media outlets including MD Edge Psychiatry, News Medical, and SciTech Daily, highlighting her contributions to understanding vascular injury in traumatic brain injury. As Medical Director of the UMMC Neuro Critical Care Unit, Dr. Parikh leads a multidisciplinary team focused on providing high-reliability, quality care with emphasis on patient experience. Her research group actively investigates cerebral hemodynamics, neuroimaging biomarkers, and clinical decision support tools for patients with acute neurological conditions, with particular attention to improving triage and interhospital transfer of neuroscience patients.

Corey TomczakView profile

Associate Professor

• Cardiovascular Physiology
• Cardiac Rehabilitation
• Heart Failure
• +4 more

Dr. Corey Tomczak is an Associate Professor in the Department of Kinesiology at the University of Saskatchewan. His research focuses on cardiovascular physiology, cardiac rehabilitation, and exercise intolerance in chronic conditions such as heart failure and congenital heart disease. He holds a PhD in Rehabilitation Medicine and has extensive postdoctoral training in the field. His work integrates clinical and physiological approaches to improve outcomes in patients with cardiovascular disorders. Affiliations: University of Saskatchewan, College of Kinesiology Research Themes: Health Aging and Management of Chronic Conditions, Child and Youth Health and Development Dr. Tomczak's research examines mechanisms underlying exercise limitations in heart failure and congenital heart disease, including autonomic regulation, vascular function, and skeletal muscle metabolism. He has trained numerous graduate students and mentors future researchers in cardiovascular physiology. His lab, the Russ Kisby Physical Activity and Health Promotion Laboratory, collaborates with clinical partners at the Royal University Hospital. Key areas of investigation include cerebrovascular responses during exercise, muscle metaboreflex modulation of cardiac function, and the impact of exercise training on cardiovascular outcomes. Recent work highlights impaired vascular function in heart failure and sex-based differences in exercise capacity.

Liam HeaneyView profile

Senior Lecturer

• Bioanalytical Science
• Analytical Chemistry
• Clinical Diagnostics
• +5 more

Liam Heaney is a Senior Lecturer in Bioanalytical Science at Loughborough University's School of Sport, Exercise & Health Sciences. He joined in 2018 through the Loughborough Excellence 100 scheme and was promoted in 2022. His expertise lies in high-throughput metabolite biomarker analysis using mass spectrometry, with applications in clinical diagnostics, sports anti-doping, and exercise performance monitoring. He holds a BSc/MSc in Sport and Exercise Science/Exercise Physiology and a PhD in Analytical Chemistry from Loughborough University. Research Interests: Development of analytical methods for small molecule metabolites Clinical and sports-related biomarker discovery Gas/Liquid Chromatography-Mass Spectrometry applications Anti-doping analysis and ethical biomonitoring Publications: Liam's work emphasizes metabolomics and ambient ionization techniques, contributing to both clinical and sports science. Recent studies focus on cannabidiol pharmacokinetics, SCFA supplementation, and TMAO metabolism in health/disease. Recipient of The Analytical Scientists 40 Under 40 Power List (2022) Labs/Teams: Active in Sport Performance and Lifestyle for Health & Wellbeing research groups. Collaborates with the John van Geest Biomarker Facility (Leicester) and NIHR Cardiovascular Biomedical Research Centre.

Tom E. NightingaleView profile

Lecturer

• Exercise Physiology
• Spinal Cord Injury Rehabilitation
• Neuromodulation
• +7 more

Dr. Tom E. Nightingale is a Lecturer in Exercise Physiology at the School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, UK. He holds a PhD from the University of Bath and has held postdoctoral positions at Virginia Commonwealth University and the University of British Columbia. His research focuses on improving health outcomes in individuals with neurological conditions, particularly spinal cord injury, through exercise and neuromodulation. Education: PhD in Exercise Physiology, University of Bath, UK (2016) BSc in Sport and Exercise Science, University of Bath, UK (2010) Dr. Nightingale's research lies at the intersection of exercise physiology and neurorehabilitation. He investigates how therapeutic interventions like neuromodulation and structured exercise can mitigate cardiometabolic and cerebrovascular risks in individuals with spinal cord injury. His work emphasizes autonomic regulation, cerebrovascular health, and the use of neuroprosthetics to enhance exercise capacity. He has published extensively on wearable technologies, clinical trial protocols, and consensus guidelines for SCI research. His recent publications highlight trends in transcutaneous spinal cord stimulation, autonomic dysreflexia prevention, and the integration of wearable devices in monitoring health outcomes. These works reflect a strong focus on translating physiological research into clinical rehabilitation strategies. Scientific Awards: Djavad Mowafaghian Centre for Brain Health Innovation Fund Postdoctoral Trainee Award Michael Smith Foundation for Health Research/ICORD Trainee Award Poster Presentation Winner, 4th International Conference on Ambulatory Monitoring Shortlisted for Ede & Ravenscroft Prize Dr. Nightingale supervises PhD and Master’s students on topics related to SCI and exercise physiology. He has received research support from the Wellcome Trust and the International Spinal Research Trust. He is actively involved in editorial boards for Spinal Cord and Spinal Cord Series and Cases , and serves on the National Rehabilitation Centre Research Board. He maintains ongoing collaborations with ICORD in Vancouver and is involved in multi-center clinical trials such as E-STAND. Labs and Teams: He collaborates with the International Collaboration On Repair Discoveries (ICORD) and contributes to research at the Centre for Human Brain Health at the University of Birmingham. His work often involves interdisciplinary teams focusing on spinal cord injury, neuromodulation, and rehabilitation science.