Find Academic Supervisors

• General Cardiology
• Pulmonary Hypertension
• Heart Failure
• +4 more

John J. Ryan is a Professor of Medicine in the Division of Cardiovascular Medicine at the University of Utah School of Medicine , specializing in General Cardiology and Pulmonary Hypertension . He holds adjunct associate professorships in Family & Preventive Medicine, Orthopaedics, and Radiology & Imaging Sciences. Dr. Ryan’s research focuses on heart failure with preserved ejection fraction , pulmonary vascular disease , and right ventricular function . His work explores statin therapy , microvascular dysfunction , and novel treatments for pulmonary hypertension . His publications emphasize cardiovascular outcomes in pulmonary hypertension, exercise physiology in heart failure, and digital health tools. He is board-certified in Advanced Heart Failure & Transplant Cardiology , Cardiovascular Disease , and Echocardiography . Clinically, he practices at the University of Utah Hospital , with consistently high patient satisfaction scores ( 4.9/5 ). His academic training includes M.D. from University College Cork , followed by residency at Boston Medical Center and fellowships at the University of Chicago Medical Center .

Reinhold J. MedinaView profile

Professor

• Vascular Biology
• Ophthalmology
• Diabetes
• +3 more

Professor Reinhold J. Medina serves as Chair Professor of Vision and Vascular Science and Head of the Department of Eye and Vision Science at the University of Liverpool's Institute of Life Course and Medical Sciences, leading research in vascular biology with emphasis on vascular ageing, diabetes complications, and regenerative mechanisms. Educational milestones include an MD from San Agustin University-Arequipa (2000) and a PhD in Stem Cell Biology from Okayama University Medical School (2006), followed by clinical training in Peru and postdoctoral work in Japan before joining Queen's University Belfast. His research program integrates cell and molecular biology to investigate endothelial progenitor cell function in diabetic retinopathy, vascular repair mechanisms, and ageing-related pathologies, with international recognition for advancing understanding of vascular dysfunction in ocular diseases. Current work focuses on metabolic regulation in endothelial cells and senescence pathways in age-related macular degeneration. Recent publications demonstrate strong interdisciplinary convergence across ophthalmology, vascular biology, and gerontology, with recurring themes in metabolic dysregulation (glycolysis), oxidative stress (NOX4), cellular senescence, and translational applications for diabetic complications and retinal diseases. Key scientific awards include: Juvenile Diabetes Research Foundation International Postdoctoral Fellowship (2008) Fight for Sight Postdoctoral Fellowship (2010) Active research grants drive innovation in dry AMD treatment through choriocapillaris senescence targeting (Macular Disease Society), RNA sensing in endothelial ageing (Leverhulme Trust), and stem cell-microengineering approaches for perfused organoids (BBSRC), reflecting strategic collaborations across vascular science, engineering, and clinical ophthalmology. He directs a multidisciplinary research team advancing vascular repair strategies through stem cell biology and molecular pathway analysis, with particular focus on translating basic discoveries into therapeutic interventions for diabetic vascular complications and age-related eye diseases.

John EberthView profile

Associate Professor

• Cardiovascular Engineering
• Biomechanics
• Mechanobiology
• +9 more

Dr. John F. Eberth is an Associate Professor at Drexel University's School of Biomedical Engineering, Science and Health Systems. As a cardiovascular engineer with expertise in mechanical controls, continuum biomechanics, and hydrogel-based extracellular matrix mimetics, he leads the Applied Biomechanics and Mechanobiology Lab (ABML) to investigate vascular behavior under mechanical stimuli. PhD in Biomedical Engineering from Texas A&M University (2008) MS in Mechanical Engineering from Clemson University (2004) BS in Mechanical Engineering from Clarkson University (2001) His research focuses on vascular pathology and mechanobiology, including: Aortopathy and aneurysm mechanics Endothelial dysfunction and arterial stiffening Hydrogel-based vascular grafts Calcification chelation therapy Coronary artery disease Perfusion tissue culture Recent publications demonstrate expertise in vascular imaging techniques, mechanical modeling, and therapeutic interventions. Key themes include drug-coated balloon development, collagen fiber mechanics, and bioreactor systems for vascular conditioning.

• Medicinal Chemistry
• Chemical Biology
• Organic Synthesis
• +3 more

Wei Shi is an Associate Professor of Chemistry (Organic) at Ball State University’s College of Sciences and Humanities, Department of Chemistry. He joined the institution in 2019, specializing in teaching Organic Chemistry and conducting research in Medicinal Chemistry, Chemical Biology, and Organic Synthesis. His research focuses on designing chemical probes derived from natural products to understand small molecule regulation of macro-biomolecules for disease treatment. Education: B.Sc. in Electrochemistry from Shanghai Jiao Tong University (China), M.Sc. in Bioorganic Chemistry from East China University of Science & Technology (China), Ph.D. in Chemistry from the University of Alberta (Canada), and postdoctoral training at Johns Hopkins School of Medicine (USA). Research Interests: Explores the pharmaceutical potential of bioactive natural products, particularly glycoconjugates, aiming to design novel drug candidates with enhanced therapeutic profiles. Key projects include studying ipomoeassin F’s mechanism of action as an ER translocon inhibitor and developing itraconazole analogs for antiangiogenic and anticancer applications. Selected Publications: Over 20 peer-reviewed articles, including landmark studies on ipomoeassin F’s Sec61α binding, itraconazole’s dual targeting of NPC1/VDAC1, and structural analog design. Recent work highlights Sec61 translocon inhibition mechanisms in Mycobacterium ulcerans pathogenesis and ER stress response modulation in cancer cells. Labs/Teams: Director of the Shi Research Group , focusing on natural product-inspired drug discovery and chemical biology.

Mansoureh EghbaliView profile

Professor

• Pulmonary Hypertension
• Myocardial Ischemia-Reperfusion Injury
• Sex Differences in Cardiovascular Disease
• +3 more

Mansoureh Eghbali, PhD, is a Professor in the Department of Anesthesiology at the David Geffen School of Medicine, University of California, Los Angeles. Her research program investigates molecular mechanisms of cardiovascular and pulmonary diseases with emphasis on sex-specific pathophysiology. She leads an active NIH-funded laboratory focused on pulmonary hypertension, myocardial ischemia-reperfusion injury, and the role of RNA-binding proteins in vascular remodeling. Her research integrates multiomics approaches to explore: Sex chromosome influences (Y-gene Uty) in pulmonary vascular protection MicroRNA regulation of cardiac fibrosis and calcification (e.g., miR-129-5p/Asporin axis) Gut-heart-lung interactions in diet-induced pulmonary hypertension Endothelial subpopulations (TM4SF1+) in disease progression Analysis of her recent publications reveals strong emphasis on: Integrative multiomics in vascular diseases Sex differences in drug responses Novel therapeutic targeting of RNA-binding proteins Cross-organ communication in cardiopulmonary pathologies She directs multiple NIH grants including: R01HL159865: Role of Chromosome Y gene, Uty (2021-2025) R01HL147586: Role of miR125 in pulmonary hypertension (2019-2023) R01HL129051: Role of miR193 in oxidized lipid-induced PH (2016-2021) R01HL131182: Epigenetic regulation by X chromosome (2016-2021)

Katrien De BockView profile

Professor

• Muscle Microenvironment
• Angiogenesis
• Metabolic Crosstalk
• +4 more

Prof. Dr. Katrien De Bock is a Full Professor and Deputy Head of the Department of Health Sciences and Technology at ETH Zurich. Her research focuses on angiogenesis, metabolic crosstalk in muscle microenvironments, and the impact of exercise on muscle regeneration. She leads a team investigating cellular interactions in skeletal muscle, particularly how metabolic signals regulate blood vessel growth and muscle repair. Key areas include understanding fibroadipogenic progenitors' role in muscle physiology, the role of histamine in exercise responses, and age-related muscle decline. Her work integrates molecular biology, single-cell transcriptomics, and computational approaches to dissect mechanisms underlying tendon pathologies, ischemic muscle injury, and metabolic adaptations to exercise. She supervises Master's programs in Human Movement Science and collaborates on projects involving muscle stem cell therapies and vascular engineering. Prof. De Bock also explores interventions like NAD+ precursors to counteract age-related sarcopenia and promotes translational research in regenerative medicine. Research Interests: Exercise-induced metabolic pathways in muscle repair Angiogenesis regulation in health and disease Hypoxia signaling in tendons and muscles Epigenetic modifications during tissue regeneration Stem cell fate determination in muscle microenvironments Notable Projects: Developing AI-driven histologic analysis for tendinopathy diagnosis Mapping the human brain vasculature at single-cell resolution Testing sulfur amino acid restriction to enhance exercise capacity

Stephen RenaudView profile

Associate Professor

• Placental Development
• Reproductive Biology
• Cellular and Molecular Mechanisms
• +3 more

Dr. Stephen Renaud is an Associate Professor in the Department of Anatomy and Cell Biology at Western University. He holds a PhD and B.Sc. from Queen's University. His research focuses on placental development and function, particularly the cellular and molecular mechanisms underlying trophoblast differentiation and maternal-fetal immune interactions. Key interests include OVO-like transcription factors, endogenous retroviral genes, and maternal immune tolerance. His work bridges basic science with public health implications, addressing complications like pre-eclampsia and fetal growth restriction. Publications emphasize placental biology, immunology, and developmental mechanisms, with contributions to journals like Placenta , Proceedings of the National Academy of Sciences , and Cellular and Molecular Life Sciences . No scientific awards are listed, but his research has been widely cited (h-index 28). He advises no listed students but maintains an active lab exploring placental biology. His office is in the Medical Sciences Building, Room 428, with contact via srenaud4@uwo.ca.

Justin Chu Jang HannView profile

Associate Professor

• Molecular RNA Virology
• Antiviral Strategies
• Viral Pathogenesis
• +3 more

Associate Professor Justin Chu Jang Hann is affiliated with the Department of Microbiology and Immunology at the National University of Singapore (NUS), within the Yong Loo Lin School of Medicine. He holds additional roles as Assistant Dean (Academic Affairs) in the School of Medicine, Director of the NUS Medicine BSL-3 & ABSL-3 Core Facility, and Joint Senior Principal Investigator at the Institute of Molecular and Cell Biology (IMCB) A*STAR. His research focuses on molecular RNA virology, antiviral strategies, and high-throughput imaging technologies to study host-pathogen interactions. Key projects include genomic screening of viral-host interactions, high-content bio-imaging platforms, and development of anti-viral compounds against pathogens like SARS-CoV-2, dengue, and enteroviruses. Recent work explores broad-spectrum antivirals, vaccine candidates, and diagnostic approaches for viral infections. His contributions span virology, immunology, and translational medicine, with a strong emphasis on combating emerging and re-emerging RNA viruses.

Pengyi YangView profile

Associate Professor

• Computational Systems Biology
• Stem Cell Biology
• Bioinformatics
• +4 more

Pengyi Yang is an Associate Professor and University of Sydney Robinson Fellow at the School of Mathematics & Statistics, University of Sydney. He leads the Computational Systems Biology group at the Charles Perkins Centre and holds a conjoint appointment as Unit Head of Computational Systems Biology at the Children's Medical Research Institute (CMRI). His research focuses on computational approaches to understand trans-regulatory networks in stem cells and their applications in regenerative medicine. Yang holds a Ph.D. and has been recognized with awards such as the National Stem Cell Foundation Metcalf Prize (2021). His research spans computational systems biology, machine learning for bioinformatics, and spatial/single-cell omics analysis. Key projects include modeling pluripotency transitions, developing stem cell-derived organoids, and creating computational tools for phosphoproteomics and multi-omics integration. Collaborations include international initiatives like the Laboratory of Data Discovery for Health (InnoHK). Yang advises multiple PhD students and leads grants on topics like stem cell-derived brain organoids and embryonic development modeling. His lab develops tools like Cepo, PhosR, and CiteFuse for omics data analysis. He teaches data science and molecular systems biology at the University of Sydney.

• Neurodevelopmental Disorders
• Autism Spectrum Disorder
• Genetic Syndromes
• +3 more

Dr. Joanna Moss is an Associate Professor in Psychology at the University of Surrey, affiliated with the School of Psychology and the Development, Education, Language and Outreach in Psychology (DevELOP) Research Group. She completed her PhD at the University of Birmingham in 2005, followed by research roles at the Institute of Psychiatry, Psychology & Neuroscience and the Cerebra Centre for Neurodevelopmental Disorders. Her research focuses on autism characteristics in individuals with genetic syndromes, employing methodologies like eye-tracking, EEG, and behavioral assessments. She has secured funding from the Academy of Medical Sciences, British Academy, and others. Dr. Moss co-chairs the Scientific and Clinical Advisory Team for the Cornelia de Lange Syndrome Foundation and advises on international research committees. She teaches a final-year undergraduate module on neurodevelopmental conditions and advises PhD students. Her lab, NDEV Research Lab, explores social-cognitive mechanisms in neurogenetic syndromes. Recent work emphasizes inclusive autism research, anxiety in high-risk groups, and machine learning approaches to phenotype analysis. Education: PhD in Psychology, University of Birmingham (2005) Roles: Senior Academic Tutor, Module Convenor for Neurodevelopmental Conditions Labs/Teams: NDEV Research Lab (www.ndevresearchlab.com) Her research highlights syndrome-specific profiles of autism traits, emphasizing the need for tailored assessments and interventions. Key findings include distinct gaze-following patterns in genetic syndromes and the role of executive dysfunction in repetitive behaviors. She advocates for ethical research practices, including preregistration in undergraduate studies.

Yulia Y TyurinaView profile

Research Professor

• Cell Death Pathways
• Lipid Peroxidation
• Ferroptosis
• +4 more

Yulia Y Tyurina serves as a Research Professor in the Department of Environmental and Occupational Health at the University of Pittsburgh. Her research focuses on the fundamental role of phospholipids and their oxygenated species in cell death pathways including apoptosis, necroptosis, ferroptosis, and mitophagy. She discovered that cardiolipin oxygenated species are essential for apoptotic execution and serve as an 'eat-me' signal for mitochondrial quality control via mitophagy. Dr. Tyurina's educational background includes: 1988: Master of Biochemistry from Saint Petersburg State University, Saint Petersburg, Russia 1995: PhD in Biochemistry from the Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Science, Saint Petersburg, Russia Her research program centers on redox lipid signaling mechanisms in cell death. She has demonstrated that phospholipid peroxidation drives ferroptosis through complex oxidation signatures and identified key roles for 15-lipoxygenase products. This work bridges basic biochemistry with translational applications in cancer, neurodegeneration, and inflammatory diseases, revealing how lipid oxidation products function as death signals across diverse biological contexts. Analysis of her 15 most recent publications (2020-2022) shows consistent focus on lipid peroxidation in ferroptosis across multiple disease models. Her work spans from cyanobacterial cell death to human pathologies including lung injury, SARS-CoV-2 complications, and cancer, with recurring mechanistic themes involving 15-lipoxygenase, cardiolipin oxidation, and mitochondrial dysfunction. Methodologies include advanced lipidomics, molecular imaging, and genetic models. Scientific awards were not mentioned in the provided information. Details about student advising and grant funding were not provided in the available text. Dr. Tyurina operates within a prominent redox biology research group led by Dr. Valerian E. Kagan at the University of Pittsburgh, maintaining extensive collaborations across departments and institutions as evidenced by her co-authorship network spanning immunology, oncology, and infectious disease research.

Fabeha FazalView profile

Associate Professor

• Pulmonary Medicine
• Cell Biology
• Molecular Pathology
• +4 more

Fabeha Fazal, Ph.D. is an Associate Professor in the Department of Pediatrics at the University of Rochester Medical Center. Her research focuses on understanding the molecular mechanisms of Acute Lung Injury (ALI)/ARDS pathogenesis, particularly how endothelial cell dysfunction and inflammation contribute to disease progression. Current lab projects explore the role of endoplasmic reticulum BiP and mitochondrial GRP75 in ALI, as well as the link between endothelial cytoskeletal dynamics and inflammatory gene expression. She employs in vitro and in vivo models, including LPS-induced sepsis and thrombin-induced inflammation , to identify novel therapeutic targets for ALI. Her publications reveal expertise in NF-κB signaling , actin cytoskeleton regulation , and organelle crosstalk in inflammatory lung disorders. She has received NIH R01 grants for studying "Regulation of Endothelial-Neutrophil Interaction and Lung Vascular Permeability in Sepsis." Education: PhD in Biochemistry, A.M. University (1992) MSc in Biochemistry, A.M. University (1987) BSc in Chemistry, A.M. University (1985) Scientific Recognition: University Gold Medal for top M.S. Examination (1987) University Gold Medal for top B.S. Examination (1985) Lab Personnel: Collaborates with Principal Investigator Dr. Arshad Rahman and post-doctoral researchers like Dr. Pei Yi Su. Lab technicians and trainees include Antony Leonard (Technical Associate) and previous graduate researcher Moyinoluwa D Adenuga.

Eric Michael BershadView profile

Professor

• Vascular Neurology
• Neurocritical Care
• Intracranial Hypertension
• +1 more

Dr. Eric Michael Bershad is a Professor in the Departments of Neurology and Neurosurgery at Baylor College of Medicine, specializing in Vascular Critical Care. He completed his medical degree at Wayne State University School of Medicine, followed by residencies and fellowships at Henry Ford Health System, University Hospitals of Cleveland, and Baylor College of Medicine. His research focuses on vascular neurology, neurocritical care, and intracranial hypertension. He has published extensively on topics including olfactory impairment in intracranial hypertension, intracranial pressure monitoring techniques, and predictors of nosocomial pneumonia in stroke patients. Dr. Bershad is board-certified in Neurology, Vascular Neurology, and Neurocritical Care. He sees patients at the Baylor Neurology Clinic at the McNair Campus in Houston.

John D. ImigView profile

Professor

• Cardiovascular Research
• Renal Physiology
• Metabolic Disorders
• +3 more

John D. Imig, Ph.D., is a Professor and Chair of the Department of Pharmaceutical Sciences at the University of Arkansas for Medical Sciences (UAMS). He holds a B.A. in Biology from Blackburn College and a Ph.D. in Physiology & Biophysics from the University of Louisville. His research focuses on understanding how fatty acids influence cardiovascular, kidney, and metabolic functions. The Imig laboratory employs advanced techniques such as animal phenotyping, 3-D/organoid cell culturing, drug design, and omics approaches to develop therapies for cardiovascular, renal, and metabolic diseases. Dr. Imig is a Fellow of the American Heart Association and American Physiological Society, and holds memberships in prestigious organizations including the American Association for the Advancement of Science and the American Society of Nephrology. He has received notable awards such as the Arkansas Research Alliance Scholar (2022), Lewis K. Dahl Memorial Lecture (2019), and the American Heart Association Established Investigator (2004). His research emphasizes multi-target drug development for metabolic diseases, renal fibrosis mechanisms, and the role of epoxylipids in hypertension. Recent studies include investigations into chemotherapy-induced kidney and heart damage, dual enzyme inhibitors, and protective agents for organ transplantation. Collaborative efforts in drug design and omics-based approaches drive translational outcomes for clinical applications. Dr. Imig leads a lab renowned for integrative research spanning basic molecular mechanisms to preclinical drug testing. His work bridges academia and industry, addressing unmet clinical needs in cardiovascular and renal therapeutics. Ongoing projects explore novel therapies targeting epoxide pathways and nuclear receptors to combat chronic diseases.

William NewmanView profile

Clinical Professor

• Pharmacogenetics
• Rare Inherited Conditions
• Genomics
• +3 more

William Newman is a Clinical Professor of Translational Genomic Medicine at the University of Manchester and Honorary Consultant at Manchester University NHS Foundation Trust. He serves as President of the European Society of Human Genetics (2024-25) and Clinical Director of the NW Genomic Medicine Service Alliance. His roles include co-leading the BRC Theme on Rare Conditions and leading the NHSE Network of Excellence in Pharmacogenetics and Medicines Optimisation. Education: BSc (hons) Experimental Immunology and Oncology MB ChB (hons) from the University of Manchester PhD in genetics from the Wellcome Trust Cell Matrix Centre MA in Healthcare Ethics and Law Research Interests: Rare Conditions : Discovery of genetic causes using next-generation sequencing, focusing on Perrault syndrome, lower urinary tract disorders, and infection-triggered neuropathies. Pharmacogenetics : Clinical implementation of genetic testing to optimize medication responses, including the PALOH study for gentamicin-induced hearing loss prevention. Lower Urinary Tract Malformations : Studies on HPSE2 and LRIG2 genes in urofacial syndrome and bladder exstrophy, supported by the MRC-NIHR Rare Disease Node (REOLUT). Genetics of Perrault Syndrome : Identification of CLPP, MRPL49, PRORP, and DAP3 genes, exploring mitochondrial dysfunction mechanisms. Spliceosomal Disorders : Investigating craniofacial syndromes like Burn McKeown syndrome using mouse and stem cell models. Key Awards: New Statesman Healthcare Positive Impact Award 2022 Times Higher Education (THE) Research Project of the Year: STEM Award 2024 Teaching and Collaborations: Established MSc in Genomic Medicine and PGCert in Clinical Genetics with international partners. Collaborates with institutions like Newcastle University, UCL, and Cambridge on rare disease projects. Leadership in European Society of Human Genetics training programs for cardiac genetics professionals. Labs and Platforms: Manchester Centre for Genomic Medicine, Manchester Regenerative Medicine Network, and the Lydia Becker Institute.