Michèle Desjardins is a Professor at Université Laval, affiliated with the CRCHU de Québec research center. Her work centers on clinical and cognitive neuroscience, focusing on advanced imaging techniques and numerical modeling to study brain activity and neurovascular coupling. Key Research Areas: Biomedical imaging, neurovascular interactions, brain aging, tumor oxygenation, and functional connectivity. Techniques: Two-photon microscopy, wide-field fluorescence imaging, optical coherence tomography, and magnetic resonance imaging (MRI). Methodologies: Biophysical oxygen transport models, Monte Carlo simulations for MRI, and artificial neural networks for data analysis. Current projects investigate age-related changes in neuronal and vascular networks, radiosensitivity in tumors, noradrenaline's role in neurovascular coupling, and structure-function relationships in the brain. She collaborates extensively on interdisciplinary neuroscience research.
Ronan Marrec is a Full Professor at the University of Picardie Jules Verne, affiliated with the Faculty of Sciences and CNRS research unit UMR 7058 EDYSAN (Ecology and Dynamic of Anthropogenic Systems). His research examines spatial and temporal dynamics of human-modified landscapes and their impacts on biodiversity across multiple scales, integrating field studies, remote sensing, and ecological modeling. Education Doctor of Biology, Ecology and Agronomy (University of Poitiers) Research Focus Marrec's work centers on landscape ecology, functional traits, and community assembly in agroecosystems and forests. He investigates how agricultural practices, landscape connectivity, and microclimate heterogeneity influence species distributions and ecosystem services, with carabid beetles serving as key bioindicators. His methodology combines empirical field data with advanced spatial modeling techniques to address conservation challenges under global change. Publication Trends Recent publications (2023-2025) reveal consistent emphasis on non-equilibrium biodiversity dynamics, landscape connectivity modeling, and microclimate-buffering effects in forests. Key themes include species distribution responses to historical land use, impacts of agrivoltaism on soil biodiversity, and functional trait-based analyses of arthropod communities across European agricultural gradients. Research Funding Current: IMPRINT & MacMiCC (microclimate impacts on forest biodiversity), SEPIM & MOTIVER (sylvo-agro-ecosystem landscape structure), IAE-Betterave & ConservES (flower strips for aphid control), Okwind (agri-photovoltaism), Bio'AUXIL (farmer knowledge transfer) Past: SUR-PAS (agro-pastoral habitat monitoring, 2018-2021), WOODNET (European forest connectivity, 2017-2020), Alberta bee community modeling Academic Leadership Since 2018, Marrec has directed the Agronomy option of the DUT Biological Engineering program at Amiens IUT, teaching courses in General Agronomy, Soil Sciences, and Agroecosystem Management while maintaining active field research collaborations across France, Italy, and Canada.
Karissa N. Arca, M.D., is an Assistant Professor of Neurology at Mayo Clinic Alix School of Medicine within the Mayo Clinic College of Medicine. She serves as a Consultant in the Division of Neuromuscular Medicine at Mayo Clinic Arizona, specializing in autonomic and headache neurology. Education: M.D. from Loma Linda University School of Medicine (2015), B.S. in Biology from Point Loma Nazarene University (2011) Certifications: Headache Medicine (2022), Neurology (2020) Dr. Arca investigates the intersection of autonomic disorders and headache medicine, focusing on postural/orthostatic headaches in cerebrospinal fluid leaks, POTS, orthostatic hypotension, and autonomic dysfunction in pectus excavatum. Her work includes respiratory pattern analysis in concussion, Sjogren's disease, and autonomic disorders, with future plans to explore neuromodulation for POTS and headache-intestinal dysmotility connections. Recent research trends show her work spans autonomic testing methodology, migraine-gut axis interactions, neuromodulation technologies, and advocacy education frameworks. Publications highlight clinical decision-making in complex headache disorders and pandemic-era medical education adaptations. Scientific Awards: Manfred D. Muenter Award (2020), Frontiers in Headache Research Award (2020), multiple scholarships from American Headache Society Professional Roles: Faculty member for Mayo Clinic neuroscience courses, Program Evaluation Committee member (2022-present), American Autonomic Society member (2021-present) Dr. Arca's patient-centered research directly informs clinical care, seeking improved treatment options through better understanding of headache-autonomic disorder phenotypes.
HanTing Zhang serves as an Associate Professor in the Department of Behavioral Medicine & Psychiatry at West Virginia University School of Medicine. His research program focuses on cyclic nucleotide signaling pathways in neurodegenerative and neuropsychiatric disorders, utilizing advanced molecular and behavioral methodologies. Research interests center on cAMP/cGMP signaling mechanisms in Alzheimer's disease, depression, anxiety, alcohol dependence, and memory disorders. His laboratory employs radial arm-maze, water-maze, forced-swim tests, alcohol drinking behavior models, brain microinfusions, immunoblotting, RNAi gene silencing (shRNAs, CRISPR-Cas9), and optogenetics to develop novel treatments targeting phosphodiesterases. Publication trends reveal specialization in phosphodiesterase inhibition (particularly PDE2, PDE4, PDE9), Alzheimer's disease mechanisms involving Cdk5 and amyloid-beta pathways, and neuroprotective strategies for stroke and multiple sclerosis. Recent work emphasizes translational approaches combining gene therapy (AAV9 vectors), kinase inhibitors (fasudil), and natural compounds. Affiliation Details: Institution: West Virginia University School: School of Medicine Department: Behavioral Medicine & Psychiatry Position: Associate Professor & Researcher Dr. Zhang's grant-supported work involves collaborative neuroscience projects with significant focus on alcohol dependence pharmacotherapy and neurodegenerative disease mechanisms. His laboratory maintains active research programs in phosphodiesterase-targeted therapeutics and neural signaling pathways. The research team operates within the Behavioral Medicine & Psychiatry department, utilizing specialized facilities for behavioral testing, molecular analysis, and neural circuit manipulation. Current projects emphasize developing CNS-targeted treatments through cyclic nucleotide pathway modulation.
Dr. Veena K. Ranganath is a practicing adult rheumatologist and clinical researcher at the David Geffen School of Medicine, University of California, Los Angeles (UCLA) . Holding the academic rank of Clinical Associate Professor in the Department of Medicine, Division of Rheumatology , she co-directs the Training Program in Translational Science (TPTS) Track 3 and directs the Rheumatology Fellowship Musculoskeletal Ultrasound Training Program . MS, BioMath, UCLA, 2010 MD, UCLA School of Medicine, 2000 Rheumatology Fellowship, UCLA School of Medicine, 2005 Internal Medicine Residency, VA Greater Los Angeles Healthcare System, 2003 Her research focuses on rheumatoid arthritis outcome measures and musculoskeletal imaging (MRI, ultrasound). Recent work includes ultrasound-guided treatment decisions , obesity-disease interaction studies , and development of automated phenotyping algorithms . Publications emphasize synovitis assessment via power Doppler and comorbidity impacts on treatment outcomes . Awarded Top Doctors by Los Angeles Magazine (2021) , she contributes to Clinical Trials like the RA-PRO PRAGMATIC TRIAL and Acthar in RA-related flares. Affiliated with Ronald Reagan UCLA Medical Center and UCLA Santa Monica Medical Center , she specializes in gout care and rheumatoid arthritis .
Verónica Contreras-Shannon, Ph.D., is a Professor of Biological Sciences at St. Mary’s University in San Antonio, Texas. She specializes in biomedical research focusing on metabolic side effects of atypical antipsychotics and cytoskeletal dynamics in disease states, particularly atherosclerosis and muscle regeneration. Her teaching portfolio includes General Biology for Majors, Toxicology, and Cell and Molecular Methods Lab, where she employs evidence-based practices like course-based research experiences to enhance student engagement. Education: Ph.D. in Biochemistry from UTHSCA (2003), B.A. in Biology from UC Santa Cruz (1995) Research Programs: Director of NIH-funded U-RISE and MARC programs for undergraduate research training Awards: Distinguished Faculty Award (2019), NIH SCORE Pilot Project Award (2018), Undergraduate Research Mentor Award (2012), Senior Faculty Research Mentoring Award (2023) Her research involves undergraduate students in studying: Mechanisms of metabolic side effects from antipsychotics Cytoskeletal roles in disease phenomena Beta-tubulin isotype involvement in foam cell formation and atherosclerosis Publications span molecular neurobiology, immunology, and biochemistry, with a focus on inflammation, muscle regeneration, and cancer biology. Contreras-Shannon is actively engaged in mentoring and serves on the American Society for Investigative Pathology Leadership Council.
Jonathan S. Bromberg, MD, PhD is the Charles Reid Edwards, MD Professor of Surgery and Professor of Microbiology and Immunology at the University of Maryland School of Medicine. He serves as Vice Chair for Research and Director of Research for the Division of Transplantation. Dr. Bromberg has maintained continuous funding for over 25 years in basic cellular and molecular transplant immunology research, while also maintaining an active clinical practice in solid organ transplantation. Dr. Bromberg's educational background includes an A.B. summa cum laude from Harvard College (1977), followed by combined MD and PhD (Immunology) degrees from Harvard Medical School and Harvard Graduate School of Arts and Sciences (1983). His postgraduate training included surgical residency at University of Washington Affiliated Hospitals and a fellowship in Transplantation at the Hospital of the University of Pennsylvania. His research focuses on T cell immunobiology, lymph node structure and function, lymphatic migration, and regulatory T cell biology in transplantation. Dr. Bromberg's laboratory has made significant contributions to understanding how lymph node structures and functions are required for tolerance induction and maintenance, the mechanisms of regulatory T cell migration and function, and the role of lymphatic vessels in immune regulation. His work has demonstrated that normal lymph node function is critical for tolerance, that regulatory T cells must migrate through lymphatics to suppress inflammation, and that specific stromal components regulate immune cell trafficking and fate decisions. Dr. Bromberg's laboratory has published extensively in top immunology and transplantation journals including Nature Immunology, Journal of Clinical Investigation, Immunity, and American Journal of Transplantation. His research group has pioneered concepts in lymphatic migration of regulatory T cells, stromal regulation of immune responses, and the role of specific laminins in transplant tolerance. His work spans basic mechanistic studies to translational applications in transplantation. Among his notable honors are the AST Basic Science Established Investigator Award (2013), NKF of Maryland Kidney Champion Award (2014), and multiple prestigious early career awards. He has served as Associate Editor for the American Journal of Transplantation and as Clinical Sciences Executive Editor for Transplantation. Dr. Bromberg has been continuously funded by NIH for over 25 years, with current R01 grants investigating lymph node structure and function in tolerance, regulatory T cell migration, and the role of microbiota in transplant outcomes. His laboratory collaborates extensively with other investigators in immunology, microbiome research, and biomaterials science.
Professor David Attwell FRS is the Jodrell Professor of Physiology at University College London (UCL) in the Faculty of Life Sciences, within the Division of Biosciences, Department of Neuroscience, Physiology and Pharmacology. He organizes the 4-year PhD program in Neuroscience at UCL and delivers undergraduate lectures. His leadership extends to university governance as he serves on the Governance Committee of Academic Board, having previously served as Vice-Head of the Graduate School and on UCL's Council. Attwell earned his D.Phil. in neuroscience from Oxford University, where he studied with Julian Jack, after completing studies in physics and physiology at Magdalen College, Oxford. He also pursued research at the University of California, Berkeley with Frank Werblin. Professor Attwell's research focuses on the intricate signaling between neurons, glial cells (including microglia, oligodendrocytes, and astrocytes), and the vasculature, with particular emphasis on how the brain's energy supply controls its computational power. His lab pioneered analyses of subcellular energy use in the brain, establishing the first comprehensive energy budgets for grey and white matter. These studies revealed that brain energy use imposes significant constraints on information processing speed, necessitating energy-saving coding strategies. His work on pericytes has demonstrated their crucial role in regulating capillary blood flow and their involvement in pathological conditions like stroke and Alzheimer's disease. Analysis of Professor Attwell's publication record reveals a strong focus on neurovascular coupling, brain energy metabolism, and glial cell function. His research spans multiple disciplines including cellular neuroscience, biophysics, and vascular biology, with particular emphasis on how energy constraints shape neural computation. The work has significant translational implications for understanding and treating stroke, Alzheimer's disease, multiple sclerosis, and other neurological conditions involving white matter damage. Professor Attwell's scientific achievements have been recognized with numerous prestigious awards: 2020 Annual Review Prize Lecture of the Physiological Society 2019 Highly Cited Scientist, Web of Science (top 0.1% of scientists) 2018 Member, Norwegian Academy of Science and Letters 2016 FENS-Kavli award for mentoring neuroscientists 2016 Fondation Ipsen Prize for Neuroenergetics 2016 Member, Academia Europaea 2010 Medal of Australian Physiological & Pharmacological Society 2001 Fellow of the Royal Society 2000 Fellow, Academy of Medical Sciences 1986 Sharpey Schafer Medal of the Physiological Society Professor Attwell actively mentors the next generation of neuroscientists, both through formal teaching and laboratory supervision. He organizes UCL's 4-year Neuroscience PhD program and participates in international teaching programs including Ion Channels workshops and the Astrocyte School. His lab has been generously supported by major funding bodies including the Wellcome Trust (Senior Investigator Award), European Research Council (Advanced Investigator Award), Medical Research Council, Fondation Leducq, and Rosetrees Trust. His commitment to outreach extends to public lectures on brain energy supply and participation in programs like In2Science, which brings underprivileged school children into research laboratories. The Attwell lab comprises a diverse team of researchers working on various aspects of neurovascular and glial biology. Current lab members investigate immune cell-vascular interactions, pericyte function in neurological and cardiac disorders, node of Ranvier dynamics, microglial properties, and the effects of diabetes on the microvasculature. The lab's collaborative approach is evident in its partnerships with researchers at UCL, King's College London, the Crick Institute, and international institutions.
Professor Sarah Berry serves as Professor of Nutritional Sciences at King's College London within the School of Life Course & Population Sciences, Faculty of Life Sciences & Medicine. With a research career spanning since 2000 at King's, she has established herself as a leading expert in precision nutrition and cardiovascular health research. Her research program focuses on how dietary components influence cardiovascular disease risk markers, with particular expertise in precision nutrition, postprandial metabolism, and food/fat structure effects. Dr. Berry has led over 35 human nutrition studies in cardio-metabolic health and serves as the lead nutritional scientist for the PREDICT programme, which assesses metabolic responses to food in more than 20,000 individuals across the UK and US. Recent publications reveal her work spans from digital health tools for menopause assessment to investigations of gut microbiome interactions with diet, interesterified fats metabolism, and food processing techniques that enhance nutrient bioavailability. Her research consistently bridges laboratory science with large-scale population studies through innovative app-based platforms like the ZOE Health Study App. Nutrition Society Silver Medal for scientific excellence Selected for final stages of Cancer Grand Challenges funding Featured in BBC One discussions on ultra-processed foods Professor Berry has been instrumental in developing app-based research platforms that combine cutting-edge research methodologies with remote clinical technologies and AI. Her work on the PREDICT programme has significantly advanced personalized nutrition approaches and continues to influence both academic research and public health recommendations. She leads ongoing research initiatives including the NutrImmune Study and the Safe and Sustainable Diets for a Healthy Body and Mind (SSuDs) Research Interest Group, demonstrating her commitment to translating nutritional science into practical health applications.
Somdeb Mitra is a Clinical Associate Professor at New York University's College of Arts and Science . His research investigates RNA-mediated gene regulation, oncogenic pathways, and therapeutic applications of RNA molecules. Key areas include RNA-protein complexes, post-transcriptional control in cancer, and development of RNA-based therapeutics. Education: Postdoctoral Research: Columbia University, New York, USA Ph.D. Biochemistry: Albert Einstein College of Medicine, New York, USA M.S. Biochemistry: Albert Einstein College of Medicine, New York, USA M.Sc. Biotechnology: Madurai Kamaraj University, India B.Sc. Zoology (Honors): Presidency College, University of Calcutta, India Research Focus: Dr. Mitra explores mechanistic aspects of RNA structure-function relationships, particularly how RNA folding and interactions regulate gene expression in diseases like cancer. His work integrates biophysical methods (e.g., analytical ultracentrifugation) with molecular biology to characterize RNA-driven oncogenesis and therapeutic targeting. Publication Trends: His 15 most recent articles (2013–2020) converge on RNA structural biology , emphasizing translation regulation, folding kinetics, and cancer applications. Dominant themes include IRES-mediated translation, RNA-protein interactions, and innovative biophysical techniques for probing RNA dynamics. Contact: Waverly Building, 24 Waverly Place, Room 437. Email: sm7274@nyu.edu .
Marco Amabili is a Professor at McGill University in the Department of Mechanical Engineering and an Associate Member in the Department of Bioengineering. He holds the prestigious Canada Research Chair (Tier 1) and leads the Vibrations and Hydrodynamics Research Group. Primary Research Theme: Vibrations, Acoustics, and Fluid-Structure Interaction Applications: Aeronautics, Aerospace, Vascular Mechanics, Civil Engineering, Energy Generation His research focuses on nonlinear vibrations and stability of shells and plates (traditional, composite, functionally graded materials, biological tissues) with fluid-structure interaction. He employs numerical/analytical tools and advanced experimental techniques like laser Doppler vibrometers, LMS modal analysis, and large water tunnels. Key research areas include: Accurate reduced-order models for bifurcation analysis Nonlinear damping investigation Signals and Systems, Biomechanics, System Identification, Modelling of Human Aorta, Dynamics and Control He is affiliated with the Fluid Structure 1 lab, which studies fluid-structure interactions involving slender structures and axial flows. The lab uses cutting-edge equipment like water tunnels, Fotonic sensors, Polytec Vibrascan systems, and FFT analyzers. Scientific honors: Canada Research Chair (Tier 1)
Caterina Rosano, MD, MPH, is a Professor of Epidemiology at the University of Pittsburgh School of Public Health, serving as Director of the MD/PhD Program in Epidemiology and Associate Director for Clinical Translation at the Aging Institute. Her research focuses on Population Neuroscience of Aging, investigating neurobiological drivers of resilience in healthy aging through advanced neuroimaging and epidemiological methods. Education: BS, Scientific Lycee B. Croce, Palermo, Italy (1989) MD, University of Palermo Medical School, Palermo, Italy (1995) Internship in Internal Medicine & Emergency Medicine, Policlinico, University of Palermo (1996) Mini Residency in Neurology, Alzheimer's Disease Research Center, UPMC (2002) MPH in Epidemiology, University of Pittsburgh School of Public Health (2003) Trainee, Epidemiology of Aging Training Program (2004) Trainee, Mentor Training Program (2010) Research Focus: Dr. Rosano pioneers the integration of neuroscience and population science to understand why some individuals age better than others. Her work reveals that microstructural brain integrity, small vessel health, and dopaminergic signaling are critical resilience factors. She demonstrates that modifiable elements like stable blood pressure and low inflammation preserve brain function, with implications for interventions targeting accelerated brain aging in conditions like diabetes. Her eBRAIN research group applies advanced MRI techniques to virtually dissect brain networks in diverse aging populations. Publication Trends: Her 2021-2022 research spans neuroimaging of aging, mobility, and health disparities. Key themes include genetic influences on gait (COMT polymorphism), vascular contributions to Parkinsonism, olfactory system changes in aging, and Alzheimer's disease disparities in minority women. Her work consistently bridges clinical neuroscience with population health, emphasizing modifiable resilience factors. Mentorship & Leadership: Dr. Rosano actively mentors trainees including postdoctoral scholar Meredith Phillips (who advocated for NIH funding at Capitol Hill 2025), PhD candidate Kailyn Witonsky, and conference-presenting students Alex Reese and Alejandra Ramirez-Tirado. She leads the eBRAIN group coordinating neuroepidemiological studies on brain resilience, recently participating in the Vanscoy Winter Academy 2025 to discuss healthy aging strategies.
C. Elizabeth Shaaban, PhD, MS, MPH, is an Assistant Professor of Epidemiology at the University of Pittsburgh School of Public Health, and serves as the Associate Director for Outreach, Recruitment, and Engagement at the University of Pittsburgh Alzheimer’s Disease Research Center (ADRC). Her interdisciplinary career spans population neuroscience, neuroimaging, and public health, with a focus on Alzheimer’s disease and related dementias (ADRD), brain health equity, and the social determinants of cognitive aging. Education 2021 – Postdoctoral Fellowship, University of Pittsburgh, Population Neuroscience of Alzheimer’s disease and related disorders 2021 – MS, University of Pittsburgh, Neuroscience 2018 – PhD, University of Pittsburgh, Epidemiology 2010 – MPH, University of Pittsburgh, Behavioral and Community Health Sciences 2001 – BS, University of Pittsburgh, Psychology Research Interests Dr Shaaban’s work integrates advanced neuroimaging with large-scale epidemiologic studies to understand the vascular, metabolic, and social factors that shape cognitive aging. She has pioneered the use of ultra-high-field 7-Tesla MRI to quantify cerebral small-vessel disease and has developed novel metrics such as unhealthy white matter connectivity to capture early cerebrovascular injury in diverse populations. A second major strand of her research addresses brain health equity , examining how race, ethnicity, gender, socioeconomic status, and life-course adversity intersect to influence dementia risk and resilience. She also leads initiatives to harmonize retrospective neuroimaging and clinical data across cohorts, creating open resources for the next generation of population neuroscientists. Scientific Awards & Recognition 2023 – International Society to Advance Alzheimer’s Research and Treatment (ISTAART) Diversity and Disparities PIA Publication of the Year Award 2022 – Alzheimer’s & Dementia Journal’s Top 10 % Most Downloaded Articles Teaching & Mentorship Dr Shaaban directs the course EPIDEM 2019: Introduction to Multimodal Neuroimaging and Applications in Population Neuroscience , and regularly guest-lectures on neuroimaging, sex/gender differences in dementia, and science communication. She mentors students and post-doctoral fellows in epidemiology, neuroscience, and public health, with a particular commitment to trainees from under-represented backgrounds. Leadership & Service As Associate Director of the ADRC Outreach, Recruitment, and Engagement Core, she oversees community-engaged research strategies designed to increase representation of minority and rural populations in ADRD studies. She co-chairs the ISTAART Diversity and Disparities Professional Interest Area Sex and Gender Special Interest Group and contributes to international guidelines on sex and gender considerations in dementia research.
Ji Xiang He is an Adjunct Associate Professor at the Department of Fisheries and Wildlife, College of Agriculture & Natural Resources, Michigan State University. He also serves as a Research Fisheries Biologist at the Michigan Department of Natural Resources (MI DNR) at the Alpena Fisheries Research Station. His professional focus integrates fish bioenergetics, food-web dynamics, and life-history parameter analysis within the context of human-ecosystem interactions in fisheries management. Education: Undergraduate in Fisheries and Aquaculture (specializing in Chinese reservoir systems), with graduate training in Fisheries and Ecology at the State University of New York (SUNY) beginning in 1995. His research bridges ecological frameworks (natural resource geography, landscape ecology, systems ecology) with quantitative fisheries science. While his primary work centers on stock assessment and ecosystem modeling in aquatic environments, recent Google Scholar publications indicate interdisciplinary applications of computational modeling and machine learning in biomedical contexts such as arterial hypertension and aneurysm progression. Key trends in his publications reveal expertise in physics-based machine learning, patient-specific hemodynamic modeling, and longitudinal data analysis for cardiovascular diagnostics. Though seemingly divergent from his fisheries background, these computational techniques may inform ecological modeling practices through cross-disciplinary methodological innovation. He maintains affiliation with the Quantitative Fisheries Center and emphasizes functional connections between ecological systems and human management practices in his work.
Kostas G. Lyketsos is a world-renowned Professor of Psychiatry and Behavioral Sciences at Johns Hopkins University , where he directs the Department of Psychiatry and Behavioral Sciences at Johns Hopkins Bayview, the Richman Family Precision Medicine Center of Excellence in Alzheimer’s Disease , and the Memory and Alzheimer’s Treatment Center . A dual clinician-scientist, he combines active patient care with cutting-edge research on Alzheimer’s disease and related dementias (ADRD). Research Focus: Neuropsychiatric symptoms in AD and dementia Biomarker development for early detection Precision medicine approaches to treatment Innovative clinical trial design Community-based dementia care models Scientific Contributions: With over 450 peer-reviewed publications (76,000+ citations, h-index 149), Dr. Lyketsos ranks #13 globally in Geriatrics (2021 Stanford study). His work spans epidemiology, neuroimaging, and therapeutic interventions, particularly targeting agitation and psychosis in dementia patients. Scientific Honors: 2022 Argo Award from the President of Greece William Proxmire Award for Alzheimer's Research Distinguished Scientist, American Association for Geriatric Psychiatry Jeanne and William E. Weinberg Award Professional Leadership: As Associate Editor of American Journal of Psychiatry and Deputy Editor of International Psychogeriatrics , he shapes field-wide discourse. His team actively develops interventions like the Tailored Activity Program for dementia care.
