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• Epigenetics
• Germline Biology
• Transcriptional Regulation
• +5 more

Dr. Bluma Lesch is an Associate Professor at Yale School of Medicine with joint appointments in Genetics and Obstetrics, Gynecology & Reproductive Sciences. She directs a research program investigating epigenetic regulation in germline development and evolutionary biology, integrating molecular, computational, and developmental approaches. Her research focuses on: Epigenetic bivalency in germ cells Transgenerational inheritance mechanisms Chromatin dynamics in meiosis Evolution of gene regulatory networks Recent publications (2024-2025) demonstrate strong emphasis on: Histone modification mechanics Germline-specific chromatin remodeling Evolutionary transcriptomics Translational studies in fertility and disease models Honors include: Pew Biomedical Scholar (2021) Searle Scholar (2019) Burroughs Wellcome Career Award (2015) NIH Kirschstein Fellowship Hope Funds for Cancer Research Fellowship She leads the Lesch Lab , which employs genomic technologies and computational modeling to study epigenetic inheritance across biological scales.

Saskia TrumpView profile

Researcher

• Epigenetics
• Molecular Epidemiology
• Environmental Health
• +3 more

Saskia Trump is a Researcher in Molecular Epidemiology at Charité Universitätsmedizin Berlin and the Berlin Institute of Health, affiliated with Irina Lehmann's Lab. Her work bridges epigenetics, environmental health, and molecular biology, focusing on how exposures like air pollution, toxins, and viral infections drive diseases such as asthma, COVID-19, hypertension, and cancer through mechanisms like DNA methylation and immune dysregulation. Her research interests include: Epigenetic Regulation: DNA methylation changes in response to environmental stressors (e.g., air pollution, maternal smoking) and their role in asthma, allergies, and transgenerational health effects. Viral Pathogenesis: Host-pathogen interactions in COVID-19, including epigenetic memory, immune responses, and comorbidities like hypertension. Cancer Metabolism: Aryl hydrocarbon receptor (AHR) signaling, tryptophan catabolism, and metabolic reprogramming in glioblastoma and other cancers. Trump's recent articles (2022–2025) emphasize SARS-CoV-2 epigenetics, pediatric health, and environmental toxicology. Trends show a strong focus on single-cell genomics, DNA methylation sequencing, and translational applications for respiratory and metabolic diseases. She collaborates extensively across disciplines, contributing to studies on cystic fibrosis, glioblastoma, and childhood asthma. Current lab projects explore: Long-term epigenetic effects of COVID-19 in airway cells. Impact of moderate air pollution on respiratory epigenomes. Metabolic-immune crosstalk in cancer progression.

• Epigenetics
• DNA Methylation
• Developmental Origins of Health and Disease
• +5 more

Professor Amanda Drake is a full-time faculty member at the Centre for Cardiovascular Science, University of Edinburgh, conducting research at the Queen's Medical Research Institute in Edinburgh BioQuarter. Her position as Professor reflects senior academic standing within the institution. Her research program investigates critical epigenetic mechanisms with focus areas: Environmental programming of DNA methylation in metabolic disease development Transgenerational inheritance of environmentally induced disease risks Neurodevelopmental outcomes following preterm birth Obesity-induced epigenetic alterations Early-life origins of neurodevelopmental disorders Professor Drake maintains an active publication record evidenced by recent work (including June 2024 publications) and supervises graduate researchers in a collaborative laboratory environment. While specific grant details aren't provided, her ongoing projects indicate sustained research funding. Students benefit from interdisciplinary training spanning molecular epigenetics, clinical epidemiology, and bioinformatics within Edinburgh's medical research infrastructure.

• Systems Immunology
• Genomics
• Artificial Intelligence
• +4 more

Prof. Dr. Joachim L. Schultze is Director of Systems Medicine at the German Center for Neurodegenerative Diseases (DZNE) and leads the Genomics & Immunoregulation group at the University of Bonn's LIMES Institute. His research integrates immunology, neurobiology, genomics, and artificial intelligence, with a focus on single-cell technologies and systems medicine approaches. Key research areas include: Swarm Learning : Development of decentralized AI frameworks for medical research NEUROCOV : Investigation of neurological complications in COVID-19 PRECISE Platform : Single-cell genomics and epigenomics technology development Systems immunology approaches for chronic inflammatory diseases Myeloid cell biology and trained immunity mechanisms His recent publications (2019-2022) demonstrate strong focus on: COVID-19 immunopathology and myeloid cell dysregulation Neuroimmunology and neurodegenerative disorders AI/blockchain applications in healthcare Single-cell transcriptomics in inflammation Metabolic regulation of immune cells Prof. Schultze coordinates multiple international consortia including the DFG-funded NGS Competence Network and Immunosensation2 Cluster of Excellence. His laboratory combines experimental genomics with computational biology at the PRECISE joint platform between DZNE and University of Bonn.

• Perinatal Epidemiology
• Fertility Research
• Assisted Reproductive Technologies
• +3 more

Siri Eldevik Håberg serves as Centre Director of the Centre for Fertility and Health (CEFH), a prestigious Centre of Excellence (SFF) funded by the Norwegian Research Council and hosted by the University of Oslo's Faculty of Medicine. Her primary institutional affiliation is with the Norwegian Institute of Public Health (FHI), where she leads cutting-edge research at the intersection of epidemiology, reproductive health, and public policy. Her research expertise spans perinatal epidemiology, with a focus on fertility problems, fetal loss, and the safety of assisted reproductive technologies (ART). She specializes in integrating national registry data, cohort studies, and biological analyses to investigate genetic and epigenetic associations with pregnancy outcomes. Current projects include large-scale studies on vaccination safety during pregnancy, environmental exposures, and transgenerational health effects. Her methodological strengths include registry-based population studies and advanced genetic epidemiology. Håberg's publication record demonstrates consistent leadership in high-impact reproductive epidemiology, with recent work examining ART outcomes, epigenetic mechanisms, and pandemic-related health impacts. Her research trends show increasing emphasis on interdisciplinary collaborations, particularly through the ERC Synergy Project on fertility in young adults and the Pregnancy and Childhood Epigenetics Consortium. Centre of Excellence (SFF) grant from Norwegian Research Council Principal Investigator for ERC Synergy Project on fertility Leadership in Nordic registry collaborations for Covid-19 research As Centre Director, she oversees substantial research funding and international collaborations, including the Norwegian Mother, Father and Child Cohort Study (MoBa). Her team comprises epidemiologists, geneticists, and clinicians working across multiple Nordic institutions. Current initiatives include clinical sampling of young adults to address declining fertility rates in Norway, reflecting her commitment to translating research into public health action.