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Derek RichardView profile

Professor

• Cancer Genomics
• Chronic Disease Genomics
• Neurogenomics
• +4 more

Professor Derek Richard is a faculty member at Queensland University of Technology (QUT), holding positions in the Faculty of Health and School of Biomedical Sciences. He serves as the Deputy Director (Industry and Commercial Engagement) at QUT's Centre for Genomics and Personalised Health and co-leads the Genomic Instability and Disease research program. Richard has a PhD and BSc (Hons) from the University of Dundee, UK, and has been an ARC Future Fellow since 2010. His research focuses on DNA repair mechanisms, genomic stability, and their roles in cancer therapy and chronic diseases. Key areas include exploring proteins like hSSB1, Banf1, COMMD4, and ALDOA as therapeutic targets and biomarkers in lung, breast, and prostate cancers. He investigates epigenetic drugs, nanoparticle-based drug delivery systems, and the effects of environmental stressors such as cold atmospheric plasma on cancer cells. Collaborations with institutions like the Centre for Genomics and Personalised Health and interdisciplinary teams highlight his commitment to translational research. Richard’s publications emphasize the clinical relevance of DNA repair pathways, metabolic influences on cancer resistance, and innovative drug delivery strategies. His work frequently addresses how disrupting DNA repair processes can enhance chemotherapy effectiveness and identifies novel targets for precision oncology. He has contributed to understanding the role of nuclear membrane proteins in tumor growth and the impact of SARS-CoV-2 on cardiac DNA damage. Scientific awards include the ARC Future Fellowship (2010–present), which supports his research into genomic instability and translational cancer therapies. His grants and collaborations span drug discovery, biomarker identification, and nanotechnology applications. Supervision of doctoral research, such as the 2016 project on nucleophosmin and genomic stability, underscores his mentorship in advancing cancer biology knowledge. Labs and teams include the Genomic Instability and Disease program at QUT, where he leads investigations into DNA repair dynamics and their clinical implications. His interdisciplinary approach integrates structural biology, computational modeling, and clinical oncology to tackle complex cancer mechanisms and develop targeted therapies.

Mark AdamsView profile

Academic

• Biochemistry and Cell Biology
• Oncology and Carcinogenesis
• Genomics
• +2 more

Dr. Mark Adams is a Senior Research Fellow at the Faculty of Health, School of Biomedical Sciences, Queensland University of Technology (QUT). With a PhD in Genomics from QUT and postdoctoral experience at the Translational Research Institute (TRI), his research focuses on exploiting cellular programs regulating genome instability, cell cycle, and growth to develop novel therapeutic strategies for lung cancers. Education: PhD (QUT), Bachelor of Applied Science (Honours) in Life Science (QUT), Bachelor of Applied Science in Biotechnology (QUT) His work published in journals like Nature Communications and Nucleic Acids Research explores: DNA repair mechanisms in cancer cells Therapeutic targeting of cell cycle regulators Spatial profiling of tumor microenvironments Computational approaches to drug discovery Scientific contributions include: Patent filings for cancer therapies Funding from NHMRC and Cancer Australia Over 10 major awards including the Young Tall Poppy Award Articles demonstrate expertise in: Lung cancer immunotherapy response prediction Novel protein interactions in DNA repair Metabolic regulation of DNA damage pathways Spatial heterogeneity in tumor biology Translational models for precision medicine

Rodney LeaView profile

Associate Professor

• Statistical Genetics
• Computational Genomics
• Bioinformatics
• +3 more

Associate Professor Rodney Lea is an academic leader in Computational Genomics at the Genomics Research Centre, Queensland University of Technology (QUT) , with adjunct research affiliations at the Hunter Medical Research Institute, University of Newcastle . He holds a PhD in Statistical Genetics from Griffith University (2002) and has 20+ years of experience in genomic data science. Research Focus: Developing bioinformatics algorithms for multi-omics analysis in complex diseases, including neurological conditions (multiple sclerosis, migraine, epilepsy), chronic kidney disease, and indigenous population genetics. His work bridges systems biology , predictive modeling , and personalised medicine . 7000+ citations (H=45) $13M+ in competitive grants (NHMRC, ARC, NIH) 17 PhD, 25 Masters/Honours students supervised Journal editorial roles (Bioinformatics, Gene) Conference leadership (GeneMappers, ANZGene)

Colleen NelsonView profile

Professor

• Prostate Cancer Research
• Translational Oncology
• Androgen Signaling Pathways
• +5 more

Professor Colleen Nelson is a leading researcher in translational prostate cancer research at Queensland University of Technology (QUT), serving as Founder and Executive Director of the Australian Prostate Cancer Research Centre - Queensland (APCRC-Q) and Chair of Prostate Cancer Research. She holds a PhD from the Australian National University and is affiliated with the Translational Research Institute (TRI) and Princess Alexandra Hospital. Her research focuses on identifying therapeutic targets for prostate cancer progression, particularly mechanisms of androgen synthesis and resistance, metabolic syndrome interactions, and clinical validation through molecular pathology. Key contributions include discovering de novo androgen synthesis in castrate-resistant tumors and pioneering the Australian-Canadian Prostate Cancer Research Alliance to enhance international collaboration. Prof Nelson has secured over $29 million in research grants, including the Queensland Government Smart Futures Fellowship. She chairs TRI’s Research Committee and Movember’s Global Scientific Committee, driving global prostate cancer initiatives. Her work integrates clinical translation, preclinical models, and genomic technologies to accelerate therapeutic development. Education: PhD (Australian National University) Leadership Roles: Director of APCRC-Q, Chair of Prostate Cancer Stream (Diamantina Health Partners), and TRI Research Committee Chair Professional Memberships: American Association for Cancer Research, Endocrine Society Her research outputs emphasize metabolic reprogramming in cancer, with recent work targeting valine catabolism and leptin signaling pathways. Collaborations include the Vancouver Prostate Centre and OncoGenex Pharmaceuticals, advancing clinical trials for novel therapies.

Brett HollierView profile

Research Fellow

• Cancer Biology
• Metastasis Mechanisms
• Epithelial-Mesenchymal Transition
• +3 more

Dr. Brett Hollier is an early career researcher leading the Invasion and Metastasis laboratory at the Australian Prostate Cancer Research Centre - Queensland (APCRC-Q), affiliated with Queensland University of Technology (QUT). He holds a QLD Smart Futures Fund Fellowship (2012-2015) focused on designing targeted therapies for cancer progression. His research centers on mechanisms of cancer metastasis, particularly the roles of insulin-like growth factor (IGF) family and epithelial-to-mesenchymal transition (EMT) in prostate cancer. Hollier earned his PhD from QUT in 2008, followed by postdoctoral training at MD Anderson Cancer Center, where he received the Susan G. Komen Foundation Fellowship. Education : - PhD, Queensland University of Technology (2008) - Postdoctoral Training, MD Anderson Cancer Center (USA) Research Interests : Hollier’s work investigates EMT-driven metastasis, therapeutic resistance, and biomarker discovery. Key areas include: - Molecular mechanisms of EMT in prostate cancer - IGF signaling and its clinical implications - Development of novel drug targets and combination therapies Grants & Awards : - QLD Smart Futures Fund Fellowship (2012-2015) - Susan G. Komen Postdoctoral Fellowship Lab & Collaborations : His lab integrates molecular biology, genomics, and clinical data to advance precision oncology. Collaborations span prostate cancer metabolism, circulating tumor cells, and immune-oncology.

• Oncology and carcinogenesis
• Genetics
• Biological sciences
• +3 more

Dr Nataly Stylianou is a Research Fellow at the School of Biomedical Sciences, Queensland University of Technology (QUT). Her research focuses on oncology, genetics, and biological sciences, with a particular emphasis on prostate cancer and placental pathobiology in SARS-CoV-2 pregnancies. Her work investigates epithelial-mesenchymal plasticity, gene expression profiling, and therapeutic resistance mechanisms. Key research interests include: Prostate cancer progression and metastasis Epithelial-mesenchymal transition (EMT) and plasticity Genetic and molecular pathways in cancer Placental dysfunction in viral infections Her publications highlight contributions to understanding BCL2 expression in advanced prostate cancer, placental pathobiology during SARS-CoV-2 infections, and the role of insulin in cancer cell migration. Recent work emphasizes therapeutic targets such as Neuropilin-1 and miRNA regulation in tumor progression. Dr Stylianou collaborates on projects involving transcriptome analysis, molecular signaling pathways, and clinical outcomes. She holds a PhD from QUT and contributes to interdisciplinary teams studying cancer biology and reproductive health.

Lisa PhilpView profile

Research Fellow

• Adipokine Research
• Prostate Cancer Therapeutics
• Metabolic Dysfunction
• +5 more

Dr Lisa Philp is a Research Fellow at Queensland University of Technology (QUT), leading the Translational Adipokine Research Group within the Australian Prostate Cancer Research Centre - Queensland (APCRC-Q). Her work focuses on adipokine hormones' role in disease, particularly prostate cancer progression and treatment resistance. She holds a PhD from the University of Adelaide and has over 13 years' experience in animal modeling and drug development. Key research areas include: Adipokine signaling pathways in cancer and metabolic disorders Preclinical development of targeted therapeutics Hyperinflammation mechanisms in respiratory diseases Awards include a US$853,896 Department of Defense grant (2020-2023) and AU$150,000 Advance Queensland Fellowship for her work on COVID-19 treatments. She collaborates with biotech firms and clinical partners globally, having secured over AUD $9.5M in competitive grants. Her projects include: Restoring adiponectin signaling to halt tumor progression Targeting leptin to combat treatment resistance Developing therapies for acute respiratory distress syndrome Dr Philp supervises 12+ students annually and chairs the TRI Cancer Seminar Series. Her industry partnerships span 6+ years, advancing 6 therapeutics from preclinical to Phase II/III trials.

• Marine Biology
• Aquaculture
• Genetics
• +3 more

Erin L. McGinty is a Researcher affiliated with James Cook University (JCU), focusing on marine biology, aquaculture, and genetic contributions to biomineralization processes. Her work centers on understanding pearl formation mechanisms in pearl oysters, particularly the genetic interactions between host and donor organisms. She holds a PhD from JCU (2011), which investigated genetic aspects of pearl formation. Her research interests include molecular biology, biotechnology applications in marine systems, and improving aquaculture practices through genetic insights. Key contributions include developing high-throughput nucleic acid quantification protocols and analyzing transcriptome data related to pearl sac biomineralization. McGinty has published extensively on pearl oyster genetics, xenograft techniques, and the interplay of genetic factors in pearl quality. Her work bridges molecular diagnostics with practical applications in the pearl industry. No scientific awards are explicitly mentioned, though her publications reflect significant academic engagement in the field. Her advising and grant details are not specified in the provided texts, but her research has been supported through collaborative projects with colleagues at JCU. While no specific lab or team affiliations are noted, her work aligns with JCU's broader marine and aquaculture research initiatives.

• Immunology
• Allergy
• Molecular Biology
• +5 more

Roni Nugraha is a researcher affiliated with James Cook University , specializing in molecular allergology and immunology. His work focuses on allergen characterization in seafood, particularly shellfish and fish, leveraging bioinformatics, proteomics, and transcriptomics to improve diagnostic accuracy. His research has led to the discovery of novel allergens (e.g., crocodile β-parvalbumin, Sydney rock oyster tropomyosin) and insights into cross-reactivity between invertebrate allergens. He co-authored the EAACI Molecular Allergology User's Guide 2.0 , a key reference in clinical allergology. Key trends in his publications include thermostable allergens in processed foods , standardization of skin prick tests , and bioinformatic approaches to allergen discovery . His collaborations with experts like Andreas L. Lopata highlight multidisciplinary teamwork in allergy research.

• Aquaculture
• Fish Nutrition
• Nutritional Physiology
• +2 more

Igor Pirozzi is a prominent researcher affiliated with James Cook University , specializing in aquaculture and fish nutrition. His work focuses on optimizing dietary specifications for marine species such as yellowtail kingfish (Seriola lalandi), barramundi (Lates calcarifer), and mulloway (Argyrosomus japonicus). Through collaborations with institutions like NSW Fisheries and Aquafin CRC, he has advanced understanding of nutrient metabolism, feed digestibility, and environmental influences on aquatic organisms. PhD in Aquaculture (James Cook University, 2009) Dr. Pirozzi's research spans two decades, investigating dietary requirements for sulfur amino acids, choline, and histidine. His studies often employ methodologies like stable isotope analysis and transcriptomic profiling to assess nutrient impacts on liver health, intestinal microbiota, and growth efficiency. Recent work highlights interactions between water temperature and dietary composition, emphasizing sustainable aquafeed formulation. The 15 most recent publications reflect a focus on nutritional physiology , feed optimization , and environmental stressors . Key subfields include amino acid sparing effects, oxygen thresholds, intestinal gene expression, and digestibility of alternative protein sources. These studies consistently address challenges in aquaculture sustainability through empirical data analysis and innovative experimental designs.

• Marine Biology
• Developmental Biology
• Genetics
• +3 more

Lauretta C. Grasso is a researcher at James Cook University, Australia, specializing in marine biology, developmental genetics, and coral reef conservation. Her work focuses on understanding coral development mechanisms, environmental stress responses, and genomic approaches to conservation. She collaborates extensively with institutions like the JCU Coral Genomics Group and has contributed to studies on coral metamorphosis, gene expression, and climate change impacts. Her research interests span molecular ecology, evolutionary biology, and the application of genomic tools to marine ecosystems. Notable projects include investigations into coral calcification under acidification, the role of Brachyury in cnidarian development, and the genetic basis of larval settlement. Grasso’s publications highlight a focus on translating molecular insights into conservation strategies. She has co-authored studies on doctoral education metrics, reflecting interdisciplinary engagement with academic policy. Her work often involves international collaborations and has advanced understanding of coral biology’s ecological and evolutionary dimensions.

• Shellfish Allergy
• Food Allergy
• Molecular Diagnostics
• +3 more

Sandip D. Kamath is a researcher at James Cook University (JCU) specializing in allergen research, particularly focusing on shellfish and fish allergens. His work bridges molecular biology, immunology, and clinical diagnostics, contributing to improved allergy management strategies. He holds a PhD from JCU and has authored/co-authored over 58 peer-reviewed publications since 2009. Research Interests: Dr. Kamath’s studies concentrate on identifying and characterizing allergenic proteins (e.g., tropomyosin, parvalbumin), developing component-resolved diagnostic tools, and exploring cross-reactivity mechanisms between food and environmental allergens. His work also addresses food safety challenges posed by seafood allergens and investigates novel therapies using bioactive compounds and probiotics. Key Findings: His research highlights geographic variability in shrimp allergens, identifies critical allergens in crustaceans and molluscs, and demonstrates the clinical utility of recombinant allergens for diagnostics. He has contributed to global guidelines on molecular allergy diagnostics through collaborative projects. Grants & Collaborations: While specific grants aren’t listed, his collaborations span institutions like the University of Queensland, Monash University, and international partners in Asia-Pacific, reflecting his role in large-scale allergenomic studies.

• Bioinformatics
• Computational Biology
• Statistics
• +6 more

Professor Michael Charleston holds a full professorship in Mathematics at the University of Tasmania's School of Natural Sciences. He specializes in bioinformatics, computational biology, and evolutionary analysis, with a focus on applying discrete mathematics and statistical methods to solve problems in life sciences and digital history. His research integrates network analysis, epidemiological modelling, and phylogenetics. Education: BSc(Hons) in Mathematics & Physics, LTCL (Music Teaching), and a PhD in Phylogenetics, all completed in New Zealand. He previously taught evolutionary biology at Oxford University and computer science/bioinformatics at the University of Sydney. Research Interests: Interdisciplinary approaches linking nutrition and social behavior in animal groups Network-based analysis of disease spread and wildlife conservation strategies Algorithm development for phylogenetic tree reconciliation and biological network alignment Genomic models for plant breeding and mangrove-wombat disease management Current Projects: Managing viral spread via partial wildlife networks In-situ control of sarcoptic mange in wombats Acoustic monitoring systems for threatened species Teaching: Graduate bioinformatics, operations research, and applied statistics courses. Supervised four completed PhD students focusing on epidemiological forecasting, protein evolution, and open-source bioinformatics ethics.

• Epilepsy
• Neurosciences
• Genetics
• +3 more

Dr. Kavitha Kothur is an NHMRC Senior Research Fellow at the University of Sydney's Faculty of Medicine and Health, affiliated with the Brain and Mind Centre and Children's Hospital at Westmead. She is a paediatric neurologist specializing in genetic testing for refractory epilepsy, functional genomics, and improving outcomes after epilepsy surgery. Her research focuses on biomarkers, neuroinflammation, and personalized medicine in epilepsy. Member of the Brain and Mind Centre Clinical specialty: Neurology Research interests include genetic epilepsies, cerebrospinal fluid biomarkers, neuroinflammatory pathways, and the psychosocial impact of genetic testing. She leads projects on epilepsy in cerebral palsy and the clinical utility of genome sequencing in refractory epilepsy. Recent articles highlight biomarkers like neopterin and quinolinic acid in neuroinflammation, genetic variants in epilepsy syndromes (e.g., SETD1B, GABRA1), and functional neurological disorders linked to psychological stressors like the pandemic. Her work bridges molecular genetics, clinical neurology, and pediatric health. Scientific awards: NHMRC Investigator Grant, NHMRC Senior Research Fellowship Collaborations include A/Prof Bruce Bennett (molecular genetics), Prof Patrick Kwan (genomics), and Prof Mary Collins (GABA receptor research). She has contributed to over 30 peer-reviewed publications since 2012, with recent focus on precision medicine strategies in pediatric epilepsy.

• Cancer Biology
• Molecular Genetics
• Ovarian Cancer
• +3 more

Eunice Lee is an Adjunct Lecturer at the School of Medical Sciences , Faculty of Medicine and Health , University of Sydney. Her primary affiliation involves research and teaching in medical sciences, with a focus on molecular oncology and genetic mechanisms in cancer progression. Research Focus: Dr. Lee investigates molecular drivers of oncogenesis, specializing in: Role of non-coding RNAs (piRNAs) in ovarian/prostate cancer Gonadotrophin receptor expression in tumor phenotypes Evolutionary adaptations in genome structure Clinical applications of molecular biomarkers Her work bridges experimental biology and clinical oncology. Publication Trends (2018-2021): Recent articles demonstrate concentrated expertise in piRNA pathway analysis across reproductive cancers, molecular diagnostics, and comparative genomics. Studies consistently integrate bioinformatic approaches with clinical data interpretation.