Lucila Ohno-MachadoView profile
Professor
Lucila Ohno-Machado, MD, PhD, MBA, is the Waldemar von Zedtwitz Professor of Medicine and Biomedical Informatics and Data Science at Yale University. She serves as Deputy Dean for Biomedical Informatics and Chair of the Department of Biomedical Informatics and Data Science at the Yale School of Medicine. Her leadership roles include overseeing informatics infrastructure for Yale’s academic health system and fostering interdisciplinary collaboration across departments such as Medicine and the Halicioğlu Data Science Institute (previously at UCSD). Ohno-Machado holds an MD from the University of São Paulo (Brazil), an MBA from Fundação Getúlio Vargas (Brazil), and a PhD in Medical Information Sciences and Computer Science from Stanford University. She has held faculty positions at Harvard Medical School, MIT’s Health Sciences and Technology Division, and the UCSD Health Department of Biomedical Informatics, where she pioneered federated learning and privacy-preserving AI methodologies. Her research focuses on predictive analytics, federated learning, quantum computing in healthcare, and blockchain applications to enhance data security. She emphasizes addressing algorithmic bias and promoting health equity through data-driven solutions. Recent work includes developing frameworks for medical device safety evaluation and guiding principles to mitigate disparities in algorithmic healthcare applications. Key achievements include the Inaugural Helen M. Ranney Award (2024), election to the National Academy of Medicine (2024), and the William W. Stead Award (2019). She has led NIH-funded informatics centers and contributed to the first large-scale clinical data-sharing initiative across five UC medical systems. Her grants span AHRQ, PCORI, NSF, and blockchain-related initiatives through the IT/NIST Challenge Award. Ohno-Machado advises on translational research strategies and mentors teams in YBIC (Yale Biomedical Informatics & Computing). Her lab collaborates globally, leveraging federated models and AI to advance personalized medicine while prioritizing patient privacy. She also chairs the OHER Awards for Yale Research Excellence, promoting interdisciplinary health equity research.








