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Rodolfo J. FloresView profile

Assistant Professor

• Behavioral Neuroscience
• Neuromodulators
• Prefrontal Cortex Function
• +3 more

Dr. Rodolfo J. Flores serves as an Assistant Professor in the Department of Psychology within the College of Liberal Arts at the University of Texas at El Paso (UTEP). His primary research investigates neuromodulator function in the prefrontal cortex, with emphasis on acetylcholine and dynorphin systems during motivational conflict, stress responses, and addiction pathways. He employs advanced optogenetic and biosensor technologies to dissect neural circuitry underlying psychiatric conditions. Dr. Flores earned his Ph.D. in Social Cognitive and Neuroscience from UTEP in 2019, followed by postdoctoral training at the National Institute of Mental Health (NIMH). His work bridges molecular neuroscience with behavioral outcomes, focusing on how stress and substance exposure alter prefrontal cortical function. His research portfolio demonstrates consistent high-impact publication in top neuroscience journals including Nature Neuroscience , Neuron , and Psychoneuroendocrinology . Current work examines opioid neuropeptide dynamics, nicotine-alcohol interactions, and sex-specific hormonal influences on addiction behaviors. Methodologically, he specializes in genetically encoded biosensors and circuit-level manipulations to study threat processing and reward pathways. Dr. Flores teaches graduate and undergraduate courses including PSYC 4341 (Motivation & Emotion), thesis/dissertation supervision (PSYC 5395/6395), and research applications courses. His lab actively trains students through undergraduate research (RSRC 4033) and independent study opportunities (PSYC 4352).

Kamal SenView profile

Associate Professor

• Neural Coding of Natural Sounds
• Hierarchical Auditory Processing
• Neural Discrimination
• +3 more

Kamal Sen is an Associate Professor in the Department of Biomedical Engineering at Boston University, serving as Director of the Natural Sounds and Neural Coding Laboratory and Director of Admissions and Recruitment for Master’s Programs. He holds a PhD and MA in Physics from Brandeis University and a BA in Physics from Bates College. His research focuses on understanding how neurons encode natural sounds, particularly in the auditory cortex. Key areas include neural coding efficiency, hierarchical auditory processing, and the role of learning in shaping receptive fields. He developed the BOSSA algorithm to address sound segregation challenges in noisy environments, with applications for hearing aid technology. Sen’s work integrates electrophysiological techniques with theoretical approaches from signal processing, information theory, and systems theory. His lab explores neural discrimination of behaviorally relevant sounds and models cortical processing dynamics using computational frameworks. Recent studies investigate parvalbumin neuron contributions to temporal coding and cortical noise reduction in complex auditory scenes. His publications span neural circuit modeling, fNIRS applications in BCI, and biomimetic algorithms for auditory scene analysis. Research highlights include exploring schizophrenia-related gene effects on neural circuits and developing 3D neurosphere models for Parkinson’s disease.

Kanwaljeet S. AnandView profile

Professor

• Pediatric Pain and Stress Neurobiology
• Neonatal and Fetal Pain Assessment
• Biomarker Development
• +3 more

Dr. Kanwaljeet S. Anand is a dual-appointed Professor of Pediatrics (Pediatric Critical Care) and Anesthesiology, Perioperative & Pain Medicine at Stanford University School of Medicine. As director of the Pain/Stress Neurobiology Lab and Jackson Vaughan Critical Care Research Fund, he serves as Editor-in-Chief of Pediatric Research and maintains active membership in Bio-X, MCHRI, and Wu Tsai Neurosciences Institute. Rhodes Scholar with D.Phil from University of Oxford Harvard postdoctoral fellowship and Boston Children's Hospital residency Founded Harmony Health Clinic - Arkansas' largest charitable medical-dental facility A translational researcher with 30+ years of impact, Dr. Anand established the first scientific framework for infant pain perception and developed novel pain assessment methodologies. Current research focuses on: Hair biomarker analysis for stress and social affiliation (cortisol/oxytocin) Machine learning systems for objective pain detection in non-verbal infants Biopsychosocial interventions for stress reduction in disadvantaged youth Neurotoxicity mechanisms of sedatives in developing brains Global NICU opioid usage patterns through the NeoOpioid Consortium His work has yielded over 260 publications and significant advances in: Pediatric pain management protocols Neonatal stress biomarker development Critical care neurobiology insights Community health initiatives AI-driven clinical decision support systems Scientific Recognition 9th Annual 'In Praise of Medicine' Public Address, Erasmus University (2014) Nightingale Excellence Award (2016) Honorary Doctorate from University of Örebro (2019) NIH SBIB-H82 Study Section Chair (2018) Multiple IASP and American Pain Society awards Swedish Academy of Medicine's Nils Rosén von Rosenstein Award (2009) St. Jude Endowed Chairholder (2010) As mentor to Med Scholar Anjali Gupta and advisor to numerous professional bodies, Dr. Anand maintains active clinical leadership in Pediatric Intensive Care while advancing computational approaches to pain detection through collaborations with Stanford's AI researchers.

Casper HoogenraadView profile

Professor

• Molecular Neuroscience
• Neuronal Development
• Intracellular Protein Trafficking
• +7 more

Prof. Casper Hoogenraad is a full professor in Molecular Neuroscience at the Department of Cell Biology, Faculty of Science, Utrecht University. His research focuses on understanding how intracellular protein trafficking underlies neuronal development and function, with particular emphasis on the microtubule cytoskeleton, synaptic cargo trafficking, and synaptic plasticity. He leads an active research group within Utrecht University's Cell Biology department and collaborates extensively with other neuroscience research groups. Education: PhD, Erasmus University Rotterdam (1996-2001) Postdoc, Massachusetts Institute of Technology (2002-2005) Hoogenraad's research spans three main themes: cytoskeleton dynamics during neurodevelopment and synaptic plasticity, motor proteins and adaptors as regulators of synaptic transport, and psychiatric and neurologic disease disorders linked to intracellular transport. His work combines genetics, biochemistry, molecular, and cellular biology methods in in vitro (neuron cultures), ex vivo (brain slices), and in vivo (mice) systems, along with advanced microscopy techniques including immunofluorescent confocal microscopy, high-resolution live cell imaging, and photo-activated localization microscopy (PALM). Analysis of Hoogenraad's recent publications reveals a strong focus on microtubule organization, neuronal polarity, and the molecular mechanisms underlying synaptic function and dysfunction. His work frequently explores how disruptions in intracellular transport contribute to neurological disorders including Alzheimer's disease, schizophrenia, and autism spectrum disorders, with particular attention to the relationship between cytoskeletal organization and cargo transport in neuronal compartments. Scientific Awards and Memberships: ZonMW-VIDI (2004) European Young Investigators (EURYI) award (2005) NWO-ALW VICI (2011) ERC Consolidator grants (2013) FENS-Kavli Network of Excellence (2014) European Molecular Biology Organization (EMBO) (2015) Young Academy of Europe (YAE) (2015) IBRO Kemali Prize (2016) Hoogenraad leads a research group studying neuronal development and function, with a particular focus on how intracellular transport mechanisms contribute to both normal brain function and neurological disorders. His laboratory employs a multidisciplinary approach combining molecular, cellular, and systems neuroscience techniques to investigate the molecular basis of neuronal polarity, synaptic plasticity, and the pathogenesis of neurological disorders. He has secured significant research funding through prestigious grants including ERC Consolidator grants. The Hoogenraad lab operates within the Cell Biology department at Utrecht University, collaborating with other research groups focusing on cellular dynamics, biophysics, and neurobiology. The lab utilizes advanced microscopy techniques including immunofluorescent confocal microscopy, high-resolution live cell imaging (spinning disc microscopy and total internal reflection fluorescence microscopy), and quantitative analysis using advanced high-resolution microscopy (photo-activated localization microscopy). Current lab technicians include Phebe Wulf and Bart de Haan.

Ruben PortuguesView profile

Professor

• Neuroscience
• Systems Neuroscience
• Behavioral Neuroscience
• +7 more

Ruben Portugues is a Professor of Brain Circuit Function and Dysfunction at the Institute of Neuroscience, Technical University of Munich (TUM). He is a full member of the Graduate School of Systemic Neurosciences (GSN), an associate and advisory board member of the Munich Center for Neurosciences (MCN), and leads a research group focused on understanding the neural basis of behavior. His lab uses larval zebrafish as a model organism to investigate sensorimotor control, decision-making, and motor learning through whole-brain imaging and circuit analysis. His research interests lie at the intersection of systems neuroscience and behavior. He investigates how brain circuits process sensory information, integrate it with motor output, and enable adaptive and flexible behavior. Key areas include the function of the cerebellum, heading direction networks, sensorimotor transformations, and the neural mechanisms of decision-making. His lab employs cutting-edge techniques including custom-built microscopes, behavioral assays, and computational analysis. The recent publications and preprints from his lab demonstrate a strong trend in decoding distributed neural circuits underlying navigation and decision-making in zebrafish. There is a clear focus on identifying specific brain regions (e.g., interpeduncular nucleus, cerebellum) and cell types involved in processing visual, motor, and spatial information. The work increasingly emphasizes whole-brain functional imaging and the emergence of cognitive-like representations such as allocentric heading direction. FENS-Kavli Network of Excellence (FKNE) PhD Thesis Prize (awarded to student Luigi Petrucco) Ruben Portugues actively mentors PhD students, including current advisees Luigi Petrucco, Ot Prat, and Shuhong Huang, and has successfully graduated Dr. Elena Dragomir and Dr. Vilim Štih. His lab engages in extensive collaborations, hosts visiting researchers, participates in teaching (e.g., CSHL Imaging Course, Cajal Course), and secures resources for advanced research. The lab is known for building its own microscopes and software, fostering technical innovation. The Portugues Lab operates as a dynamic, interdisciplinary team that combines experimental neuroscience with computational and engineering approaches. They regularly hold retreats, participate in scientific events, and contribute to community initiatives like the Munich Brain Day. The lab is preparing to relocate to the Department of Neurobiology and Behavior at Cornell University, marking a new phase in its research trajectory.

Rishidev ChaudhuriView profile

Associate Professor

• Computational Neuroscience
• Neural Dynamics
• Cognitive Neuroscience
• +3 more

Rishidev Chaudhuri is an Associate Professor at the University of California, Davis in the Department of Neurobiology, Physiology and Behavior within the College of Biological Sciences. His research focuses on computational neuroscience and neural dynamics, employing mathematical models to investigate how neural circuits generate cognitive processes such as memory, perception, and decision-making. His work explores neural dynamics through models of memory systems, attentional mechanisms, and probabilistic inference. Recent publications highlight advances in understanding hippocampal memory scaffolds, parietal-frontal interactions, and neuromorphic computing inspired by brain architecture. Education: BA in Physics (Amherst College), PhD in Applied Mathematics (Yale University) Centers: Center for Neuroscience; affiliated with Applied Mathematics and Neuroscience Graduate Groups Scientific awards and honors are not explicitly mentioned in the provided materials.

• Neurobiology
• Synaptic Plasticity
• Molecular Genetics
• +7 more

Prof. Stephan J. Sigrist is a Full Professor of Genetics at the Institute of Biology, Free University of Berlin. His lab focuses on synaptic active zone architecture, neuroplasticity, and aging-related neurodegeneration. He leads the Collaborative Research Center 958 on Membrane Scaffolding and co-directs NeuroCure, a DFG Cluster of Excellence at Charité. Education: PhD in Molecular Genetics (1997) and Habilitation (2005) from the University of Göttingen. Positions: Einstein Professor (2014–present), Spokesperson CRC 958 (2012–present), and Co-Director NeuroCure (2009–present). Research explores presynaptic mechanisms using Drosophila and mouse models, combined with STED microscopy. Key contributions include discoveries of Bruchpilot's role in active zones and spermidine's protective effects against age-related synapse decline. Grants: Over €6 million in funding, including DFG CRCs, Einstein Foundation, and ERC Advanced Grant (2025). Awards: Einstein Professorship, Best Habilitation Award, EMBO/HFSP Fellowships. Collaborations span structural biology (e.g., Stefan Hell), neurophysiology (David DiGregorio), and aging research (Frank Madeo).

Teresa PuthusseryView profile

Associate Professor

• Retinal Neurobiology
• Neurophysiology
• Retinal Degeneration
• +3 more

Dr. Teresa Puthussery is an Associate Professor in the School of Optometry & Vision Science at the University of California, Berkeley. Her research focuses on retinal neurobiology and neurophysiology, investigating how visual signals are encoded in healthy retinas and disrupted during degeneration. She uses advanced techniques like patch-clamp electrophysiology, immunohistochemistry, and microscopy to study retinal circuits, neurotransmitter receptors, and ion channels. Dr. Puthussery teaches courses on vision science anatomy, physiology, and problem-based learning, including VISION SCIENCE 206B/C and 260C. Her research explores questions such as how retinal neurons extract motion/spatial details, how photoreceptor mutations cause degeneration, and how inner retinal circuits adapt post-photoreceptor loss. Recent work includes studies on ON-type direction-selective ganglion cells, optogenetic therapy for vision restoration, and calcium dynamics in foveal ganglion cells post-degeneration. She collaborates on projects involving primate and rodent models, contributing to understanding retinal disease mechanisms and therapeutic targets. Dr. Puthussery’s lab (retinalab.berkeley.edu) emphasizes translational research, bridging basic science and clinical applications. Her work has been published in journals like Nature and Cell Reports , with a focus on retinal degeneration, synaptic plasticity, and optogenetic interventions. She actively participates in training future vision scientists through Berkeley’s Optometry program and oversees GSI affairs as a faculty advisor.

• Neuroscience
• Cognitive Neuroscience
• Memory Processes
• +4 more

Simon Hanslmayr is a Professor in the School of Psychology & Neuroscience at the University of Glasgow. His research investigates neural oscillations' role in attention and memory processes, employing EEG, fMRI, and transcranial stimulation techniques. He focuses on healthy populations and clinical conditions like Schizophrenia and PTSD. His lab develops tools like the Brain Time Toolbox for electrophysiological data analysis. Education: Ph.D. in Cognitive Neuroscience (not explicitly detailed in text) Research interests include understanding how precise neural timing via oscillations underpins cognitive functions. Key areas: hippocampal memory coding, theta phase synchronization in associative memory, and causal effects of rhythmic stimulation on memory plasticity. Recent articles highlight mechanisms linking theta oscillations to memory formation, thalamocortical interactions in perception, and hippocampal-neocortical coupling. His work bridges experimental and computational approaches to model memory dynamics. Grants: Sensory stimulation for memory impairment (BIAL Foundation, 2025-2026) EU-funded studies on neural oscillations and memory (2020-2021) Awards: None explicitly listed, but active grant recipient. Supervised students include Kiera Capstick, Eleonora Marcantoni, and others. Collaborates with researchers worldwide through lab affiliates and visiting scholars. Current work emphasizes scalable neurotechnologies for cognitive enhancement and memory rehabilitation. Labs/Teams: Leads the Memory & Oscillations Lab at the University of Glasgow, collaborating with institutions like the University of Zurich and Maastricht University on neuroimaging and clinical studies.

Alicia CheView profile

Assistant Professor

• Neuroscience
• Developmental Neuroscience
• Behavioral Neuroscience
• +5 more

Alicia Che is an Assistant Professor of Psychiatry at Yale University School of Medicine and serves as Director of Graduate Admissions for the Interdepartmental Neuroscience Program. She joined the Yale Department of Psychiatry in 2021 after completing her postdoctoral fellowship with Dr. Natalia De Marco García at Weill Cornell Medical College and Dr. Gord Fishell at NYU. Her research is conducted through the Che Lab at Yale, where she investigates how early life experiences impact brain circuit assembly and mature function in models of psychiatric illness. Yale School of Medicine, Department of Psychiatry Interdepartmental Neuroscience Program Center for Brain & Mind Health Division of Molecular Psychiatry Wu Tsai Institute Yale Center for the Science of Cannabis and Cannabinoids Dr. Che earned her Ph.D. in Physiology and Neurobiology from the University of Connecticut in 2014, where she worked in the laboratory of Dr. Joseph LoTurco. She received her B.S. with triple majors in Biology, Physics, and Physical Chemistry from Pacific Lutheran University in Washington state in 2009. Her research focuses on understanding developmental trajectories following early life experiences to develop diagnostics and early interventions for psychiatric illnesses. Dr. Che's research examines how sensory inputs, social bonding, stress, and substance exposure impact brain development. She employs a multi-dimensional approach to assess transcriptional, circuit, neuronal activity, and behavioral changes across the entire developmental timeline. Her lab currently focuses on four specific areas: the role of oxytocin in social behavior development, circuit dysfunction in PTSD, early-life cannabinoid exposure effects, and the impact of early life stress on development and adulthood. She utilizes advanced techniques including mouse genetics, slice electrophysiology, and longitudinal in vivo 2-photon imaging on behaving animals. Her most recent publications demonstrate significant contributions to understanding neural circuit development, PTSD mechanisms, and the effects of early life experiences on brain function. Her work spans from molecular neuroscience to behavioral outcomes, with publications in top journals including Nature, Neuron, and Nature Communications. Her research has revealed important insights into how translaminar neuronal activity strengthens cortical columns, how oxytocin facilitates social touch development, and how PTSD affects brain transcriptomics. NARSAD Young Investigator Award (2020) K99/R00 Pathway to Independence Award from NINDS (2019) Dr. Che's work has significant implications for understanding and treating neurodevelopmental disorders, PTSD, and the consequences of early life experiences on mental health. She collaborates extensively with researchers across Yale and beyond, with frequent co-authorship with colleagues including Lin Lin, Alex Kwan, and Christopher Pittenger. Her research program bridges basic neuroscience with clinical applications, aiming to translate findings into potential interventions for psychiatric conditions.

Miaoqiang LyuView profile

Research Fellow

• Solar Energy
• Photocatalysis
• Flexible Electronics
• +3 more

Dr. Miaoqiang Lyu is a Research Fellow at the School of Chemical Engineering , The University of Queensland . His work focuses on lead-free perovskites , flexible energy storage , and optoelectronic devices . Research Interests : Designing low-toxicity and stable semiconducting lead-free perovskites for solar energy conversion Developing flexible energy storage devices for Internet-of-Things (IoT) sensors Advancing zinc batteries and aqueous electrolyte systems Photocatalytic hydrogen production and CO2 reduction Recent Article Trends : Focus on 2D/3D heterostructures, interstitial metal doping, and solvent-engineered interfaces Applications in indoor photovoltaics, artificial synaptic functions, and wearable electronics Lead-free perovskites for resistive memory and energy storage Scientific Awards : ARC DECRA Fellow Advance Queensland Industry Research Fellow CRC for Polymers grant Supervision & Funding : Principal advisor for two PhD projects on lead-free perovskites and flexible batteries Current grants: Enabling low-toxicity perovskites for indoor photovoltaics (2026-2030), Printable zinc ion batteries (2025-2026) Labs & Collaborations : Affiliated with the Nanomaterials Centre at UQ Collaborations with Professor Lianzhou Wang , Professor Ian Gentle , and Associate Professor Ruth Knibbe

• Computational Neuroscience
• Neural Networks
• Retinal Computation
• +7 more

Joel Zylberberg is an Adjunct Assistant Professor at the University of California, Los Angeles (UCLA), affiliated with the Department of Ophthalmology within the School of Medicine . His research bridges Computational Neuroscience , Neural Networks , and Machine Learning , focusing on how neural activity and biological mechanisms inform artificial intelligence and visual cortex dynamics . Joel's work explores retinal computation , population coding , and neural adaptation , often analyzing mouse visual cortex and neurophysiological data . His recent publications highlight trends in dynamic retinal processes , stimulus-driven network topology , and brain-inspired machine learning , emphasizing the interplay between biophysics and computational modeling . Collaborators include Greg Field (UCLA), Richard Born (Harvard), and Michael DeWeese (UC Berkeley), with affiliations spanning institutions like University of Washington and University of California, San Diego (UCSD). His work appears in journals such as Nature Neuroscience , Neuron , and PLOS Computational Biology .

• Neuroscience
• Neurodegenerative Diseases
• Alzheimer's Disease
• +3 more

Hideyuki Takahashi is an Associate Research Scientist in the Department of Neuroscience at Yale University School of Medicine. He holds a PhD from Waseda University (2005) and has established himself as a prominent researcher in neurodegenerative diseases, particularly focusing on lysosomal biology and protein aggregation mechanisms. Dr. Takahashi's research primarily investigates the role of progranulin, TMEM106B, and other molecular players in neurodegenerative conditions including Alzheimer's disease, frontotemporal dementia, and tauopathies. His work spans multiple approaches from molecular and cellular neuroscience to animal models of disease. His recent publications demonstrate a strong focus on lysosomal dysfunction in neurodegeneration, with particular attention to how TMEM106B interacts with other proteins to influence disease progression. The research trends show increasing emphasis on therapeutic interventions targeting specific molecular pathways involved in protein aggregation and synaptic loss. ORCID: 0009-0004-4969-977X Dr. Takahashi maintains active collaborations with several leading researchers at Yale, most notably with Stephen Strittmatter (with whom he has 16 common publications), as well as Anita Huttner, Anthony Koleske, and Le Zhang. His research program appears well-integrated within Yale's neuroscience community, contributing significantly to our understanding of neurodegenerative disease mechanisms.

Philippe CampeauView profile

Associate Clinical Professor

• Medical Genetics
• Bone Dysplasias
• Skeletal Dysplasias
• +12 more

Dr. Philippe Campeau is an Associate Clinical Professor in the Department of Pediatrics at the Faculty of Medicine, Université de Montréal. He is affiliated with CHU Sainte-Justine, a major pediatric hospital in Montreal, Quebec, where he works in the Medical Genetics Service. His clinical and research work focuses on genetic disorders affecting children, particularly in the areas of skeletal development and neurogenetics. Dr. Campeau obtained his Doctorate in Medicine from Laval University in Quebec (1998-2003) followed by specialty training in medical genetics at McGill University (2003-2008). He completed postdoctoral training at Baylor College of Medicine (2008-2013), which further developed his expertise in genetic research methodologies. His primary research interests include bone dysplasias , skeletal dysplasias , epilepsy , and epigenetic diseases . Dr. Campeau's laboratory identifies disease-causing genes, deciphers disease pathophysiology, and works to improve the management of children affected by these conditions. His work encompasses exome analysis , functional studies with cell lines and mouse models , and investigations into urea cycle abnormalities . He has made significant contributions to understanding genetic causes of conditions such as Genitopatellar syndrome (KAT6B), osteopetrosis, dysosteosclerosis (SLC29A3), osteogenesis imperfecta, early-onset osteoporosis (WNT1), Yunis-Varón syndrome (FIG4), and DOORS syndrome (TBC1D24). Dr. Campeau's publication record demonstrates a strong trajectory in medical genetics research, with numerous high-impact publications spanning from fundamental genetic discovery to translational research. His work spans skeletal disorders, neurodevelopmental conditions, and epigenetic mechanisms. Recent publications indicate an expanding focus on chromatin modifiers, DNA methylation patterns, and spliceosome function in neurodevelopmental conditions, reflecting the evolution of his research interests toward more complex molecular mechanisms. Dr. Campeau has received several research grants in recent years (6 starting in 2014) from organizations including the Fonds de la recherche en santé du Québec, Canadian Institutes of Health Research, and Fondation Grand Défi Pierre Lavoie. While specific students are not mentioned in the available information, as a clinical professor, he mentors medical students, residents, and research trainees in the Department of Pediatrics. His research is conducted as part of the 'Musculoskeletal Diseases and Rehabilitation' axis at CHU Sainte-Justine Research Center, where he collaborates with international research teams to identify disease-causing genes and develop better management strategies for children with genetic disorders.

Manu SharmaView profile

Associate Professor

• Neuroscience
• Neurodegenerative Diseases
• Synaptic Transmission
• +5 more

Manu Sharma is an Associate Professor of Neuroscience at the Brain and Mind Research Institute , Weill Cornell Medical College (2024–present). His research focuses on the molecular mechanisms underlying neurodegenerative diseases, particularly tauopathies and synucleinopathies (e.g., Alzheimer’s and Parkinson’s diseases), synaptic transmission, and protein aggregation. Education: Ph.D., University of Toronto (2005) B.Sc., University of Toronto (1998) Research Interests: Dr. Sharma investigates how physiological and pathological modifications of tau and α-synuclein proteins contribute to neurodegeneration. His work explores synaptic vesicle dynamics, chaperone-mediated protein stabilization, and the role of lysosomal pathways in disease progression. Grants: He has secured major funding as Principal Investigator and Co-Investigator from the National Institute on Aging and National Institute of Neurological Disorders & Stroke (2024–2029) for studies on tau proteostasis, synucleinopathies, and small molecule inhibitors targeting neurodegenerative pathways. Labs & Teams: Affiliated with the Brain and Mind Research Institute, Dr. Sharma collaborates on multidisciplinary projects involving synaptic biology, protein quality control, and neurodegeneration models.