Super Resolution Microscopy Professors and Supervisors | ApplySharif

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Peter McCourtView profile

Professor

UiT The Arctic University of NorwayNorway

Peter McCourt is a Professor in the Department of Medical Biology at UiT The Arctic University of Norway. His research focuses on liver sinusoidal endothelial cells (LSECs), their role in scavenging pathogens and toxins, and the application of advanced microscopy techniques to study cellular ultrastructure. Key areas include aging-related changes in LSEC function, nanotherapeutic delivery systems targeting the liver, and the interplay between hemodynamics and liver architecture. Research interests span liver biology, endothelial cell biology, and biomedical imaging innovations. His work combines experimental and computational approaches to understand how LSECs regulate blood filtration, immune responses, and metabolic processes. Notable contributions include developing optical microscopy methods like transparent polymer waveguide chips for super-resolution imaging and investigating nanoparticle-mediated drug delivery to rejuvenate aged liver cells. Publications highlight advancements in correlative microscopy, fenestration dynamics in LSECs, and the role of stabilin receptors in scavenging oxidized proteins and viral particles. His research bridges basic science and translational medicine, addressing applications in aging populations and infectious diseases.

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Song WenView profile

Senior Lecturer

Middlesex UniversityUnited Kingdom

Dr. Song Wen is a Senior Lecturer in Biomedical Sciences at Middlesex University's Department of Natural Sciences. Her interdisciplinary research integrates biomedical science with nanotechnology and artificial intelligence to develop novel diagnostic and therapeutic approaches for cancer, particularly HPV-related cancers. Her research focuses on developing advanced drug delivery systems using liposomal nanotechnology, creating 3D tissue models for cancer research, and applying deep learning techniques to medical imaging for viral detection. She explores nanocarrier optimization for targeted cancer therapy, particularly using compounds like arsenic trioxide and baicalein. Dr. Wen's recent publications demonstrate expertise in developing deep learning algorithms for HPV detection in microscopy images, optimizing liposomal drug formulations for cervical cancer treatment, and evaluating natural compound synergies for leukemia therapy. Her work bridges computational approaches with experimental biomedical research. She contributes to educational initiatives in biomedical sciences and mentors students in interdisciplinary research methodologies that combine laboratory experimentation with computational analysis.

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Jordan BeachView profile

Associate Professor

Loyola University ChicagoUnited States

Jordan Beach is an Associate Professor of Cell & Molecular Physiology at Loyola University Chicago's Stritch School of Medicine. The Beach Lab investigates how cells generate and regulate contractile forces through myosin motor proteins, particularly during cell migration and division. Research employs advanced imaging techniques including: Super-resolution microscopy for myosin dynamics High-resolution live-cell imaging Quantitative analysis of cytoskeletal organization Current research themes include: Regulation of myosin filament assembly and amplification Integration of contractile units into functional networks Metabolic control of cellular contractility Tissue-specific contractile mechanisms Recent publications demonstrate innovations in understanding actomyosin organization and its implications for cellular mechanics and disease processes.

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Janosch HellerView profile

Assistant Professor

Dublin City UniversityIreland

Dr. Janosch Heller is an Assistant Professor of Biomedical Sciences at Dublin City University's School of Biotechnology, with affiliations as an Honorary Lecturer at University College London's Queen Square Institute of Neurology and a visiting scientist at the Royal College of Surgeons in Ireland. He holds an Irish Research Council Laureate and Marie Skłodowska-Curie Fellowships. His research integrates molecular biology, biochemistry, and super-resolution microscopy to study astrocyte dysfunction in neurological diseases, particularly epilepsy and neurodegeneration. Key areas include astrocyte control of waste clearance, synaptic plasticity, and microRNA regulation. Education: Diplom in Biology (University of Cologne, Germany), PhD in Clinical Neurosciences (University of Cambridge). Postdoctoral work at UCL and RCSI advanced his expertise in neuroimaging and translational neuroscience. His lab at DCU focuses on developing novel therapeutic strategies targeting astrocytes. Scientific awards include the Irish Research Council Laureate and Marie Skłodowska-Curie Fellowship. Research has led to breakthroughs in astrocyte-nanotechnology and glial-neuronal interactions. Collaborations span institutions in Ireland, UK, and Germany.

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Roger SherView profile

Assistant Professor

Stony Brook UniversityUnited States

Roger Sher is an Assistant Professor at the Renaissance School of Medicine, Stony Brook University. His research focuses on neurodegenerative diseases, particularly ALS, with three main themes: nuclear transport defects' role in neurodegeneration, interactions between genetics and environmental toxicants in ALS, and retrotransposons' impact on neuronal health. He uses mouse models, cell cultures, and biochemical analyses to explore these areas. His lab, located in the Centers for Molecular Medicine, investigates how genetic mutations (e.g., NEMF, dynactin p150Glued) and environmental toxins contribute to disease progression. Key findings include identifying quantitative trait loci affecting ALS survival in mouse models and demonstrating triclosan's disruptive effects on mitochondrial structure. Dr. Sher's work emphasizes interdisciplinary approaches, combining molecular genetics, cellular biology, and developmental biology. His recent studies highlight the potential of retrotransposon activation as a therapeutic target in ALS and the importance of ribosome-associated quality control in neuromuscular diseases.

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Akiko NishiyamaView profile

Professor

University of ConnecticutUnited States

Akiko Nishiyama is a Professor in the Department of Physiology and Neurobiology at the University of Connecticut. Her research focuses on the molecular and cellular mechanisms of NG2 glial cells (oligodendrocyte precursor cells), their interactions with neurons, and roles in CNS development and repair. She leads the Nishiyama Lab, utilizing mouse genetics, RNA sequencing, and advanced microscopy techniques. Her work is supported by NIH/NINDS and the European Union’s Horizon 2020 program. Education: M.D., Nippon Medical School Ph.D., Niigata University, Japan Research Interests: Her lab explores OPC lineage plasticity, neuron-glial communication, and the functional roles of OPCs beyond myelination. Techniques include super-resolution microscopy, whole-genome profiling, and behavioral analyses of mutant mice. Past contributions include defining OPC lineage restrictions and their interactions with microglia. Funding & Awards: NIH/NINDS Grant EU Horizon 2020 Marie Curie Grant (NG2 Cells Project) Lab & Team: Key team members include long-term lab manager Youfen and PhD students Bobby Hill and Ethan Hughes. Recent milestones include a 2023 review in Cold Spring Harbor Perspectives in Biology and collaborative work on oligodendrocyte development in Seminars in Cell & Developmental Biology.

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Simon TrowitzschView profile

Research Fellow

Goethe-University FrankfurtGermany

Dr. Simon Trowitzsch is a Group Leader at the Institute of Biochemistry at Goethe-University Frankfurt, where he also serves as a Senior Scientist collaborating with Prof. Robert Tampé. His research focuses on ribonucleoprotein complexes, antigen processing mechanisms, and enabling technologies for studying multiprotein complexes. He holds a PhD in Biochemistry from Georg-August University Göttingen and Max-Planck Institute for Biophysical Chemistry, and a Diploma in Biochemistry from Georg-August University. Dr. Trowitzsch leads a team (TrowitzschLab) investigating fundamental aspects of gene expression and immune system function. His work integrates structural biology, molecular biology, and advanced biophysical techniques. Notable achievements include structural studies of the MHC-I peptide-loading complex and discoveries in tRNA splicing ligase mechanisms. Research Interests: Ribonucleoprotein complexes in gene expression Antigen processing pathways in adaptive immunity Development of tools for multiprotein complex analysis Key Awards: Marie-Curie Intra-European Fellowship (2010–2012) Max-Planck Research Stipend (2008–2009) Funding: DFG Grant on tRNA Biogenesis Associated Member of Collaborative Research Center 902 His group actively collaborates with institutions like the European Molecular Biology Laboratory (EMBL) and employs cutting-edge methods such as cryo-EM and mass spectrometry. Future work aims to bridge structural insights with functional studies of immune-related complexes.

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Nathan AlderView profile

Professor

University of ConnecticutUnited States

Nathan Alder is a Professor in the Department of Molecular and Cell Biology at the University of Connecticut (UConn), with a focus on Structural Biology, Biochemistry, and Biophysics. His research explores mitochondrial biology, membrane protein function, and lipid dynamics using advanced spectroscopic and imaging techniques. Education: PhD from University of California, Davis; postdoctoral training at Texas A&M University and Stanford University. His work integrates experimental and computational methods to study protein trafficking, cardiolipin-mediated processes, and mitochondrial dysfunction in disease. Research interests include mitochondrial protein import mechanisms, mitochondrial membrane biophysics, and the development of nanodisc technologies for membrane protein analysis. Key projects involve investigating the therapeutic potential of mitochondria-targeted peptides and understanding the role of lipid composition in mitochondrial function. Publications span over 20 years, with recent work focusing on SS-31 (Elamipretide) mechanism of action, mitochondrial energetics in aging, and cardiolipin's role in complex II assembly. His lab has pioneered techniques for reconstituting membrane proteins into nanodiscs and applying super-resolution microscopy to study mitochondrial ultrastructure. Labs/Teams: Alder Lab (alderlab.mcb.uconn.edu), collaborating with experts in biochemistry, biophysics, and computational biology. Active in training graduate students and postdocs in mitochondrial systems biology.

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Xiaogang LiuView profile

Assistant Professor

Singapore University of Technology and DesignSingapore

Xiaogang Liu is an Assistant Professor at the Singapore University of Technology and Design (SUTD). He leads the Fluorescence Research Group, focusing on developing fluorescent compounds for bioimaging, biosensing, and energy applications, as well as combating food fraud through fluorescence fingerprinting. His work includes creating novel fluorophores and analyzing their applications in oils, wines, and other products to detect adulteration. Liu holds a BEng in Electrical and Electronic Engineering from Nanyang Technological University (2006), an MSc/MEng in Materials Science and Engineering from NUS/MIT (2009), and a PhD in Physical Chemistry from the University of Cambridge (2014). He previously worked as a Product Engineer at Linear Technology and as a Singapore-MIT Alliance for Research and Technology Scholar. His research emphasizes molecular engineering to design tailored fluorescent properties for practical applications, including collaborations with organic chemists and industry partners. Education: BEng (NTU 2006), MSc/MEng (NUS/MIT 2009), PhD (Cambridge 2014) Research Interests: Fluorescent materials, bioimaging, food safety, and molecular design Notable Projects: Development of fluorescence fingerprints for detecting gutter oil, ratiometric probes for lysosomal imaging, and photostable dyes for long-term cell tracking Students: Advises PhD students like Shen Tianruo (recipient of RSC awards) and Supphachok Liu's lab explores techniques like excitation-emission matrices and tetrazine-based probes for bioorthogonal imaging. His innovations in fluorogenic labels and photostable materials advance applications in diagnostics, environmental monitoring, and biotechnology. The group actively seeks collaborations and Ph.D. candidates.

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Ana DoblasView profile

Assistant Professor

University of Massachusetts DartmouthUnited States

Ana Doblas, PhD, is an Assistant Professor in Electrical and Computer Engineering at the University of Massachusetts Dartmouth. She holds a PhD in Physics from the University of Valencia (2015), an MSc in Advanced Physics (2011), and a BSc in Physics (2010). Her Optical Imaging Research Laboratory develops multimodal imaging platforms and computational methods for biomedical applications. Research interests include: Digital holographic microscopy reconstruction algorithms Low-cost diagnostic imaging systems 3D super-resolution microscopy Automated image processing pipelines She has received NSF CAREER and industry funding for developing accessible microscopy technologies. Current projects focus on improving resolution and accessibility of optical imaging for healthcare applications.

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Tahir IssaView profile

Assistant Professor

San José State UniversityUnited States

Tahir Issa is an Assistant Professor in the Department of Mathematics and Statistics at San José State University's College of Science. His research spans Data Science, Machine Learning, Deep Learning, Statistics, and Mathematical Biology with a focus on chemotaxis models and medical imaging applications. He holds a Ph.D. in Mathematics and actively contributes to interdisciplinary research at the intersection of computational methods and life sciences. Research Interests: Dr. Issa's work integrates theoretical mathematics with applied machine learning. Key areas include developing deep learning algorithms for medical imaging (e.g., fluorescence microscopy and mammography auditing), analyzing chemotaxis-driven biological systems (e.g., population dynamics and competitive species models), and applying statistical methods to environmental and civil engineering challenges. His mathematical biology research emphasizes stability analysis and pattern formation in heterogeneous environments. Publications Trends: His recent work demonstrates expertise in both computational modeling (e.g., U-Net architectures for cell segmentation, GANs for super-resolution imaging) and theoretical analysis of PDE systems in chemotaxis. The 2023–2025 articles highlight advancements in medical imaging automation and healthcare-related machine learning applications. Grants & Advising: While specific grants are not listed, his active publication record suggests ongoing research funding. He advises students in interdisciplinary projects combining mathematics, data science, and biology. No awards are explicitly mentioned in the provided text. Labs & Teams: Affiliated with the Mathematics and Statistics Department's research groups focused on applied mathematics and data science initiatives.

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Nian WangView profile

Associate Professor

University of Texas Southwestern Medical CenterUnited States

Nian Wang is an Associate Professor in the Advanced Imaging Research Center at UT Southwestern Medical Center, specializing in the development of novel quantitative MRI techniques for central nervous and musculoskeletal systems. His research bridges high-resolution diffusion MRI, artificial intelligence, and spatial transcriptomics. Key research areas include: Microscopic-resolution diffusion tensor imaging Quantitative susceptibility mapping Multimodal integration of MRI with light sheet microscopy AI-enhanced super-resolution reconstruction Neurodegenerative disease characterization His recent publications demonstrate leadership in preclinical MRI methodology, with 2024-2025 works establishing ISMRM standards for diffusion MRI and advancing extracellular vesicle diagnostics for Alzheimer's disease. Article trends show progressive innovation in 3D volumetric reconstruction, molecular signature characterization, and clinical translation of quantitative imaging biomarkers. He maintains active research in kidney microstructure mapping, meniscal collagen architecture analysis, and developing mouse brain atlases through advanced computational integration.

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Amro HamdounView profile

Professor

University of California, San DiegoUnited States

Amro Hamdoun is a Professor at the Center for Marine Biotechnology and Biomedicine within the Scripps Institution of Oceanography at the University of California, San Diego. His research integrates marine biology, developmental genetics, and environmental toxicology using sea urchin models to address fundamental questions in embryogenesis and pollutant impacts. Education: B.S., University of California, Davis Ph.D., University of California, Davis Research Focus: Dr. Hamdoun investigates plasma membrane dynamics during embryonic development through live-cell and super-resolution imaging. His pioneering work on ABC transporters examines their critical roles in embryonic protection against environmental toxins, alongside studies of emerging marine pollutants and persistence prediction methods. Key research areas include Developmental Biology of Marine Organisms , Environmental Toxicology , Physiology of Marine Organisms , and Population Genetics . His lab develops advanced techniques for gene editing, cryopreservation, and high-throughput imaging in marine model systems. Publication Trends: Recent work (2023-2025) demonstrates heavy emphasis on Lytechinus pictus sea urchin models for studying embryonic development, immune responses, and pollutant effects. Major themes include CRISPR/Cas9 genome editing, ABC transporter function, cryopreservation techniques, and computational analysis of developmental processes. His research bridges marine biology with human health through studies of conserved molecular pathways. Laboratory: Dr. Hamdoun leads the Center for Marine Biotechnology and Biomedicine research group, developing genetically-enabled marine model systems to investigate fundamental biological processes with implications for environmental health and biomedical research.

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Silvio RizzoliView profile

Professor

University of GöttingenGermany

Professor Silvio Rizzoli directs the Department of Neuro- and Sensory Physiology at the University Medical Center Göttingen, specializing in super-resolution microscopy techniques to investigate synaptic function at the nanoscale. Holds a PhD in Physiology from the University of Colorado (2004) and leads research on synaptic vesicle recycling using STED microscopy. His groundbreaking work enables visualization of sub-synaptic structures below the diffraction limit. Research employs STED microscopy to map synaptic vesicle pools and protein domains, developing novel imaging probes and correlative methods like NanoSIMS. Recent work focuses on ultra-resolution techniques combining expansion microscopy with fluctuation analysis to achieve molecular-scale resolution. Honored as Fellow of the Royal Society of Edinburgh. Leads ERC Synergy and FET-OPEN projects developing next-generation nanoscopy including ONE Microscopy and Imageomics platforms. Manages core facilities including NanoSIMS 50L and coordinates international collaborations across physics, chemistry, and neuroscience disciplines.

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Robert H. SingerView profile

Professor

Albert Einstein College of MedicineUnited States

Robert H. Singer is a Professor and Co-Chair of Anatomy & Structural Biology, Professor of Cell Biology and Neuroscience at Albert Einstein College of Medicine. He holds the Harold and Muriel Block Chair in Anatomy & Structural Biology and co-directs the Gruss Lipper Biophotonics Center and the Integrated Imaging Program. His research focuses on RNA dynamics, including single-molecule imaging of mRNA from transcription to degradation, and developing advanced microscopy techniques. He leads a lab renowned for innovations in fluorescent RNA labeling and real-time tracking of mRNA trafficking in living cells. Research Interests: Dr. Singer’s work centers on understanding RNA expression, localization, and translational regulation. His lab pioneered methods to visualize RNA in living cells using fluorescent probes and super-resolution microscopy, enabling the study of mRNA behavior in neurons, fibroblasts, and yeast. Key topics include RNA localization mechanisms, stress granule formation, and the impact of mRNA dynamics on health and disease. Patents: He has authored numerous patents, including technologies for RNA visualization (e.g., US Patent #6,586,240), multi-fluor FISH assays, and in-situ hybridization methods. These innovations underpin his lab’s contributions to biotechnology and diagnostics. Lab & Collaborations: The Singer Lab collaborates widely, advancing tools for studying HIV latency, coronavirus replication, and RNA-protein interactions. His team includes over 50 current and former trainees, reflecting a commitment to mentoring the next generation of scientists. Publications: Recent work spans topics like mRNA stability in yeast, intercellular RNA transfer, and imaging techniques for neurodegenerative diseases. Over 200+ publications highlight his lab’s interdisciplinary impact in cell biology, neuroscience, and biophysics.

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